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Delivery systems for hydrophobic drugs

  • US 5,645,856 A
  • Filed: 06/06/1995
  • Issued: 07/08/1997
  • Est. Priority Date: 03/16/1994
  • Status: Expired due to Term
First Claim
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1. A pharmaceutical composition comprising:

  • (a) a hydrophobic drug comprising progesterone, and(b) a drug carrier system comprising;

    (i) a digestible oil, and(ii) a pharmaceutically acceptable surfactant for dispersing the oil in vivo upon administration of the carrier system, said surfactant comprising a hydrophilic surfactant component, and being such that it does not substantially inhibit the lipolysis of the digestible oil, said pharmaceutical composition comprising from 0.1% to 50% by weight of said hydrophobic drug and correspondingly from 50% to 99.9% by weight of said drug carrier system.

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