Edge-effect electrodes for inducing spatially controlled distributions of electrical potentials in volume conductive media

• US 5,649,970 A
• Filed: 08/18/1995
• Issued: 07/22/1997
• Est. Priority Date: 08/18/1995
• Status: Expired due to Term

• Current Assignee: Advanced Bionics AG (Sonova Holding AG)
• Original Assignee: Gerald E. Loeb, Helen Ruddy
• Inventors: Ruddy, Helen, Loeb, Gerald E.
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/516,758
• Time in Patent Office: 704 Days
• Field of Search: 607/55-58, 607/67, 607/72, 607/115, 607/116, 607/119, 607/122, 607/123, 607/125, 607/136, 607/137
• US Class Current: 607/57
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0541 Cochlear electrodes
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance

Abstract

An electrode array for implantation in volume-conductive media, such as living tissue, includes at least two closely spaced metal contacts, with arbitrary shapes, having large enough surface areas to preclude one or both from acting as a "point source." Through proper control of the shape of the contacts, and the impedance ratio between the metal-electrolyte interface and the intervening volume-conductive media, achieved through use of appropriate materials for the metal contacts in combination with electronic adjustment of the voltage pulse applied between the contacts, desirable "edge-effect" fields are created that better control and manage the distribution of the resulting stimulation current flowing between the contacts. Such control of the stimulation current distribution allows a given electrode array to be electronically tuned to better stimulate specific neurons found within the tissue. One embodiment of the electrode array includes a plurality of single, relatively small, contacts, each having its own lead attached thereto, that lie in close proximity to a highly elongated contact, having a single lead attached thereto. When an electrical potential pulse is applied between a given one of the small contacts and the elongate contact, most of the current flow through the elongated contact occurs in a small region on its surface immediately adjacent to the nearby contact. In such embodiment, N perpendicular bipolar fields are thus created using only N+1 leads.

Claims

1. A functional electrical stimulation (FES) system comprising:

an electrode array comprising;

a flexible carrier,

a single, elongate electrode contact positioned on said carrier, and

a multiplicity of individual electrode contacts that are spaced apart from each other a distance d on said carrier, where d is less than about 1.2 mm, said individual electrode contacts also being spaced apart from said elongate electrode contact,

said carrier having a general spiral shape, thereby forming a spiral-shaped electrode array, the elongate electrode contact being positioned on the carrier so that it lies along an inside edge of the spiral-shaped electrode array, said electrode array being positionable within volume-conductive media of a cochlea of a human ear; and

means for selectively applying a pulsed electrical current between said elongate electrode contact and at least one of said multiplicity of individual electrode contacts so as to create a gradient field through the volume-conductive media, said gradient field creating a current density in the volume-conductive media, elongate electrode contact, and at least one individual electrode contact, said current density appearing as a bipolar stimulation between the at least one individual electrode contact and a small portion of the elongate electrode contact adjacent the at least one individual electrode contact;

said means for selectively applying a pulsed electrical current comprising an implantable cochlear stimulator that includes power/data receiving means for receiving power and data from a non-implanted transmitter, and stimulation control means for applying the received power as an electric potential between selected ones of said multiplicity of individual electrode contacts and said elongate common electrode contact as controlled by the received data, thereby selectively creating the gradient field through the volume-conductive media as controlled by the received data.

2. The FES system as set forth in claim 1 wherein said elongate electrode contact is made from a material having spring-like properties that help maintain the spiral shape of said electrode array.

3. The FES system as set forth in claim 1 wherein at least one of said multiplicity of individual electrode contacts and said elongate common electrode contact have surfaces comprising activated iridium, thereby reducing interfacial impedance of the electrode contacts when interfaced with volume-conductive media.

4. The FES system as set forth in claim 1 wherein all of said multiplicity of individual electrode contacts and said elongate electrode contact have surfaces comprising activated iridium.

5. The FES system as set forth in claim 1 wherein the stimulation control means of the implantable cochlear stimulator includes means for applying the pulsed electrical current between the elongate electrode contact and a selected one of the individual electrode contacts at one instant of time, and for rapidly selecting others of the individual electrode contacts in a prescribed sequence at other instants of time, whereby the pulsed electrical current is never applied to more than one of the individual electrode contacts at the same time.

6. The FES system as set forth in claim 1 wherein the stimulation control means of the implantable cochlear stimulator includes means for simultaneously applying the pulsed electrical current between the elongate electrode contact and a selected plurality of the individual electrode contacts, whereby the gradient field created in the volume-conductive media is shaped by the pulsed electrical current applied to the selected plurality of individual electrode contacts and the spacing of the individual electrode contacts so as to create a virtual electrode contact in a region intermediate the selected plurality of individual electrode contacts to which the pulsed electrical current is applied.

7. An electrode system for providing electrical stimulation to a desired location within volume-conductive media, comprising:

an implantable electrode array comprising a plurality of closely spaced metal contacts separated by less than about 10 mm, at least one of said metal contacts being coated with a coating of activated iridium, each metal contact having means for making electrical contact therewith, and each having a sufficient area to not function as a point source;

anti-corrosion means for preventing each of said metal contacts from corroding in the presence of a high current density at an edge of said metal contacts; and

means for inducing an electric field between a pair of said plurality of metal contacts so that, when volume-conductive media is inserted therebetween, a high density electrical current flows from a portion of an edge of one of said metal contacts of said pair through the volume-conductive media to the other metal contact of said pair, whereby an edge-effect electrical current flow is induced between the pair of metal contacts.

8. The electrode system of claim 7 wherein the anti-corrosion means further includes means for reducing the interfacial impedance of the metal contacts of the electrode array when interfaced with the volume-conductive media.

9. The electrode system as set forth in claim 7 wherein said anti-corrosion means comprises a coating of an oxide of tantalum metal placed on at least one of said metal contacts of said array.

10. The electrode system of claim 7 further including means for controlling the induced electric field so that the edge-effect electrical current flow is directed to a desired region within the volume-conductive media;

whereby edge-effect electrical currents are used beneficially in a closely spaced bipolar metal contact configuration.

11. The electrode system of claim 10 wherein the means for controlling the induced electric field comprises means for applying a pulsed electric potential between a selected pair of said plurality of metal contacts, and means for adjusting a pulse width of said pulsed electric potential.

12. The electrode system of claim 11 wherein said electrode array includes:

at least one elongate metal contact,

a plurality of smaller metal contacts, and

a non-conductive carrier that holds said elongate metal contact in a fixed spaced-apart relationship relative to the plurality of smaller metal contacts, and wherein

corresponding portions of each of the plurality of smaller metal contacts are approximately equidistant from an edge of said elongate metal contact, and further wherein

said means for controlling the induced electric field so that the edge-effect electrical current flow is directed to a desired region within the volume-conductive media comprises means for selectively energizing a first pair of said plurality of metal contacts with an electric potential for a first pulsed time period, energizing a second pair of said metal contacts with an electric potential for a second pulsed time period, and continuing to energize a respective pair of said metal contacts with an electric potential for a specified pulsed time period, in a defined sequence, with only one pair of metal contacts being energized with an electric potential at any given instant of time, and wherein one of the metal contacts of each pair of metal contacts thus energized comprises the elongate metal contact, and wherein the direction of the current flow into a desired region of the volume-conductive media is a function of the pulsed time period of the electric potential applied to a given pair of metal contacts and the defined sequence in which the pairs of metal contacts are energized.

13. The electrode system of claim 12 wherein said non-conductive carrier has a spiral shape having an inside edge, and wherein said elongate metal contact lies on the inside edge of the spiral-shaped carrier.

14. An implantable electrode array comprising:

an elongate, non-conductive, flexible, resilient carrier formed into a desired shape;

a multiplicity of spaced-apart small electrodes formed on said carrier, each having a separate wire connected thereto, the wires from all of said small electrodes passing through said carrier to a proximal end thereof whereat electrical contact may be selectively made with each of said wires; and

an elongate common electrode formed along one side of said carrier, said elongate common electrode having an additional wire connected thereto that passes through said carrier to its proximal end whereat electrical contact may be made therewith, said elongate common electrode having folds to provide a plurality of high points and low points along its length between adjacent ones of said small electrodes;

whereby an electrical potential may be selectively applied between a selected one of said multiplicity of small electrodes and said common electrode by selectively applying the electrical potential to appropriate wires at the proximal end of said carrier, said electrical potential creating a spatial distribution of electrical fields that, when the electrode array is inserted into a volume-conductive media, causes an electrical stimulating current to flow through the media between the selected small electrode and a small area of the elongate common electrode adjacent the selected small electrode, thereby effectively providing bipolar stimulation between the selected small electrode and the small area of the elongate common electrode adjacent thereto, and

whereby a multiplicity of bipolar electrode sites may be provided through selective application of a voltage potential to appropriate ones of said wires.

15. The electrode array as set forth in claim 14 wherein at least one of said multiplicity of small electrodes and said elongate common electrode have surfaces coated with activated iridium, thereby reducing interfacial impedance of the electrodes when interfaced with volume-conductive media.

16. The electrode array as set forth in claim 15 wherein all of said multiplicity of small electrodes and said elongate common electrode have surfaces comprising activated iridium.

17. The electrode array as set forth in claim 14 wherein said multiplicity of small electrodes are spaced apart a distance d on said carrier, where d is less than about 1.2 mm.

18. The electrode array as set forth in claim 14 wherein there are at least fifteen small electrodes formed on said carrier.

19. An electrode system for providing electrical stimulation to a desired location within volume-conductive media, comprising:

an implantable electrode array comprising

at least one elongate metal contact,

a plurality of smaller metal contacts, and

a non-conductive carrier that holds said elongate metal contact in a fixed spaced-apart relationship relative to the plurality of smaller metal contacts, said non-conductive carrier having a spiral shape having an inside edge, and

wherein corresponding portions of each of the plurality of smaller metal contacts are approximately equidistant from an edge of said elongate metal contact, and further

wherein said elongate metal contact lies on the inside edge of the spiral-shaped non-conductive carrier;

means for inducing an electric field between a pair of metal contacts that includes said at least one elongate metal contact and a selected one of the plurality of smaller metal contacts so that, when volume-conductive media is inserted between the pair of metal contacts, a high density electrical current flows from a portion of an edge of said elongate metal contact through the volume-conductive media to the smaller metal contact of said pair, whereby an edge-effect electrical current flow is induced between the pair of metal contacts; and

means for controlling the induced electric field so that the edge-effect electrical current flow is directed to a desired region within the volume-conductive media, said means for controlling the induced electric field comprising means for selectively energizing a respective pair of said metal contacts with an electric potential for a specified pulsed time period in a defined sequence, with only one pair of metal contacts being energized with an electric potential at any given instant of time, and wherein the direction of the current flow into a desired region of the volume-conductive media is a function of the pulsed time period of the electric potential applied to a given pair of metal contacts and the defined sequence in which the respective pairs of metal contacts are energized, whereby edge-effect electrical currents are used beneficially in a closely spaced bipolar metal contact configuration.

20. An implantable electrode array comprising:

a elongate, non-conductive, flexible, resilient carrier formed into a desired shape;

a multiplicity of spaced-apart small electrodes formed on said carrier, each having a separate wire connected thereto, the wires from all of said small electrodes passing through said carrier to a proximal end thereof whereat electrical contact may be selectively made with each of said wires; and

an elongate common electrode formed along one side of said carrier, said elongate common electrode having spring-like properties that impart the desired shape to said resilient carrier, said elongate common electrode further having an additional wire connected thereto that passes through said carrier to its proximal end whereat electrical contact may be made therewith;

whereby an electrical potential may be selectively applied between a selected one of said multiplicity of small electrodes and said common electrode by selectively applying the electrical potential to appropriate wires at the proximal end of said carrier, said electrical potential creating a spatial distribution of electrical fields that, when the electrode array is inserted into a volume-conductive media, causes an electrical stimulating current to flow through the media between the selected small electrode and a small area of the elongate common electrode adjacent the selected small electrode, thereby effectively providing bipolar stimulation between the selected small electrode and the small area of the elongate common electrode adjacent thereto, and

whereby a multiplicity of bipolar electrode sites may be provided through selective application of a voltage potential to appropriate ones of said wires.

21. An implantable cochlear electrode array comprising:

a elongate, non-conductive, flexible, resilient spiral-shaped carrier formed to fit within a cochlea of a human ear;

a multiplicity of spaced-apart small electrodes formed on said carrier, each having a separate wire connected thereto, the wires from all of said small electrodes passing through said carrier to a proximal end thereof whereat electrical contact may be selectively made with each of said wires, and wherein said multiplicity of small electrodes are spaced apart a distance d on said carrier, where d is less than about 1.2 mm; and

an elongate common electrode formed along one side of said carrier, said elongate common electrode having an additional wire connected thereto that passes through said carrier to its proximal end whereat electrical contact may be made therewith;

whereby an electrical potential may be selectively applied between a selected one of said multiplicity of small electrodes and said common electrode by selectively applying the electrical potential to appropriate wires at the proximal end of said carrier, said electrical potential creating a spatial distribution of electrical fields that, when the electrode array is inserted into a volume-conductive media, causes an electrical stimulating current to flow through the media between the selected small electrode and a small area of the elongate common electrode adjacent the selected small electrode, thereby effectively providing bipolar stimulation between the selected small electrode and the small area of the elongate common electrode adjacent thereto, and

whereby a multiplicity of bipolar electrode sites may be provided through selective application of a voltage potential to appropriate ones of said wires.

22. The electrode array as set forth in claim 21 wherein the elongate common electrode is positioned on the spiral-shaped carrier so that it lies along an inside edge of the spiral-shaped carrier.