Method for retrieving pancreatic juice utilizing and endoscopically wire-guided catheter

• US 5,651,769 A
• Filed: 10/16/1995
• Issued: 07/29/1997
• Est. Priority Date: 10/16/1995
• Status: Expired due to Fees

• Current Assignee: BETH Israel Medical Center (Mount Sinai Beth Israel)
• Original Assignee: BETH Israel Medical Center (Mount Sinai Beth Israel)
• Inventors: Waxman, Irving, Freedman, Steven
• Primary Examiner(s): Rimell, Sam
• Assistant Examiner(s): WINGOOD, PAMELA LYNN
• Application Number:
  US08/543,612
• Time in Patent Office: 652 Days
• Field of Search: 604/280, 604/51, 604/54, 604/96, 604/101, 128/753, 128/754, 606/167, 606/170, 600/104
• US Class Current: 604/540
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00

Abstract

A method for accurately and quickly positioning a double lumen gastroduodenal tube into predetermined locations utilizing an endoscopically placed guide wire to retrieve duodenal fluid uncontaminated by gastric fluid, with little or no discomfort to the patient, and minimal radiation exposure. Specifically, an endoscope is passed through a patent'"'"'s esophagus and stomach into the duodenum such that its distal end is located at a predetermined location, such as the fourth portion of the duodenum. While the endoscope is held in place, a guide-wire is passed through its center instrument channel to position a distal end of the guide-wire adjacent to the distal end of the endoscope. The endoscope is then withdrawn from the patient, leaving the guide-wire. A double lumen gastroduodenal tube is then threaded over the guide-wire such that gastric ports are aligned with the stomach and duodenal ports are aligned with the fourth portion of the duodenum so that upon aspiration of the gastric ports, the gastric fluid is prevented from entering the duodenum and contaminating the duodenal fluid.

Claims

1. A method for positioning a double lumen gastroduodenal tube into a patient to diagnose chronic pancreatitis, comprising the steps of:

(a) passing a distal end of an endoscope from an external body access site to a predetermined location of an duodenum;

(b) passing a guide-wire through said endoscope to position a distal end of said guide-wire proximate to said distal end of said endoscope;

(c) withdrawing said endoscope from the patient;

(d) passing a double lumen gastroduodenal tube over said guide-wire to position a distal end of said tube proximate to said distal end of said guide-wire such that ports of a first lumen are located in stomach and ports of a second lumen in said predetermined location of said duodenum; and

(e) withdrawing said guide-wire from the patient.

2. The method of claim 1, further comprising the step of:

(f) before said step (a), sedating the patient.

3. The method of claim 1, wherein said predetermined location is a fourth portion of said duodenum.

4. The method of claim 1, wherein said predetermined location is distal to the ampulla of vater.

5. The method of claim 1, wherein said step (b) is performed under fluoroscopic guidance.

6. The method of claim 1, wherein said step (c) includes the step of:

1) confirming said distal end of said guide-wire is proximate to said distal end of said endoscope.

7. The method of claim 6, wherein said step (c) (1) is performed with fluoroscopy.

8. The method of claim 1, further comprising the step of:

(f) lubricating said guide-wire after said step (c).

9. The method of claim 1, further comprising the step of:

(f) after said step (d) and before said step (e), verifying said position of said double lumen gastroduodenal tube such that said distal end of said second lumen is in said predetermined location of said duodenum.

10. The method of claim 9, further comprising the steps of:

(g) securing said tube after said step (e).

11. A method for obtaining duodenal fluid for use in diagnosing chronic pancreatitis of a patient, comprising the steps of:

(a) passing a distal end of an endoscope through the patient'"'"'s esophagus and stomach to a predetermined location of an duodenum;

(b) passing a guide-wire through said endoscope to position a distal end of said guide-wire proximate to said distal end of said endoscope;

(c) withdrawing said endoscope from the patient;

(d) passing a double lumen gastroduodenal tube over said guide-wire to position a distal end of said tube proximate to said distal end of said guide-wire such that gastric ports of a first lumen are positioned in stomach and duodenal ports of a second lumen are positioned in said predetermined location of said duodenum;

(e) withdrawing said guide-wire from the patient;

(f) continuously aspirating gastric fluid from said gastric ports; and

(g) periodically aspirating duodenal fluid from said duodenal ports.

12. The method of claim 11, further comprising the step of:

(h) performing a secretin stimulation test during said step (g).

13. The method of claim 11, further comprising the step of:

(f) before said step (a), sedating the patient.

14. The method of claim 11, wherein said predetermined location is the ampulla of vater.

15. The method of claim 11, wherein said step (c) includes the step of:

1) confirming said distal end of said guide-wire is proximate to said distal end of said endoscope.

16. The method of claim 11, further comprising the step of:

(f) after said step (d) and before said step (e), verifying said position of said double lumen gastroduodenal tube such that said distal end of said second lumen is in said predetermined location of said duodenum.

17. A method for obtaining duodenal fluid for use in diagnosing chronic pancreatitis of a patient, comprising the steps of:

(a) passing a distal end of an endoscope through the patient'"'"'s esophagus and stomach to a predetermined location of an duodenum;

(b) passing a guide-wire through said endoscope to position a distal end of said guide-wire proximate to said distal end of said endoscope;

(c) withdrawing said endoscope from the patient;

(d) passing a gastroduodenal tube over said guide-wire to position a distal end of said tube proximate to said distal end of said guide-wire such that duodenal ports of said tube are positioned in said predetermined location of said duodenum;

(e) passing a tube having a balloon at its distal end over said gastroduodenal tube to position said balloon at a location between said stomach and an entry point at which the pancreatic juice enter said duodenum;

(f) inflating said balloon to prevent gastric fluids from entering said predetermined location of said duodenum;

(g) withdrawing said guide-wire from the patient; and

(h) periodically aspirating duodenal fluid from said duodenal ports.

18. The method of claim 17, further comprising the step of:

(f) before said step (a), sedating the patient.

19. The method of claim 17, wherein said predetermined location is the ampulla of vater.

20. The method of claim 17, further comprising the step of (f) performing each of said steps (a) through (e) under fluoroscopic guidance.