Spyrosorbent wound dressings for exudate management

• US 5,653,699 A
• Filed: 09/13/1994
• Issued: 08/05/1997
• Est. Priority Date: 09/13/1994
• Status: Expired due to Term

• Current Assignee: Innovative Technologies, Incorporated (Valmont Industries Incorporated)
• Original Assignee: PolyMedica Industries, Inc. (ATLS Acquisition LLC)
• Inventors: Reed, Andrew M., Potter, Jon M., Szycher, Michael
• Primary Examiner(s): Milano, Michael J.
• Application Number:
  US08/305,273
• Time in Patent Office: 1,057 Days
• Field of Search: 604/304, 604/307, 604/368, 604/369, 604/372, 602/41, 602/44-48, 602/58, 602/59
• US Class Current: 604/307
• CPC Class Codes: A61F 13/023 wound covering film layers without a fluid retention layer
• CPC Class Codes: A61F 2013/0074 containing foams
• CPC Class Codes: A61F 2013/00748 with hydrocolloids or superabsorbers wound bandages with alginate A61F2013/00229; plasters with cyano-acrylic adhesive A61F2013/00459; plasters for treating burn with hydrogel A61F2013/00523; adhesive for plasters, with hydrogel A61F2013/00676; water-based A61F2013/00689; for use on mucosae A61F2013/00714; for use on wounds A61F2013/00719; with absorbent adhesives A61F2013/00757; with fumed silica A61F2013/00787; with viscoelastic oil-elastomer gel A61F2013/00893
• CPC Class Codes: A61F 2013/00876 vapour permeability >500 g/mg/24h

Abstract

A sheet-form composite suitable as a spyrosorbent wound dressing and exhibiting differential moisture vapor transport rate properties is disclosed. The sheet-form composite includes a hydrophilic, monolithic film layer characterized by having a differential ratio of wet to dry moisture transport rate greater than 1 and a dry moisture transport rate greater than about 2,600 g/m² /24 hrs. This film layer is laminated to a hydrophilic exudate transport layer. The exudate transport layer can itself be, or can further include, a hydrophilic pressure sensitive adhesive applied in a continuous or discontinuous pattern. The sheet-form composite has a moisture vapor transport rate of greater than 2,000 g/m² /24 hrs when dry, and a wet to dry moisture vapor transport rate ratio in the range of about 1.5 to about 10.

Claims

1. A sheet-form composite suitable as a spyrosorbent wound dressing which comprises:

(a) a monolithic, hydrophilic film layer characterized by having a moisture vapor transport rate of greater than about 2,600 g/m² /24 hrs when dry and a wet to dry moisture vapor transport rate ratio greater than 1 and (b) a hydrophilic and absorptive exudate transport layer contiguous with at least a portion of the film layer, the exudate transport layer providing a wound contacting face for the sheet-form composite, the moisture vapor transport rate of the composite being greater than 2,000 g/m² /24 hrs when dry, and greater than about 3,000 g/m² /24 hrs when wet.

2. The sheet-form composite of claim 1 further including a pressure sensitive adhesive layer on at least a portion of the wound contacting side of the sheet-form composite.

3. The sheet-form composite of claim 1 wherein the wet to dry moisture vapor transport rate ratio of the sheet-form composite is in the range of about 1.5 to about 10.

4. The sheet-form composite of claim 1 wherein the wet to dry moisture transport rate ratio of the sheet-form composite is in the range of about 2.5 to about 5.5.

5. The sheet-form composite of claim 1 wherein the film layer is a segmented polyetherurethane urea resin.

6. The sheet-form composite of claim 1 wherein the film layer has a thickness of less than about 5 mils (about 125 microns) when dry.

7. The sheet-form composite of claim 1 wherein the film layer has a thickness of about 1 mil (about 25 microns) to about 1.5 mils (about 37.5 microns) when dry.

8. The sheet-form composite of claim 1 where the exudate transport layer is selected from the group consisting of a hydrocolloid, a gel, a foam, a membrane, a textile, an adhesive and combinations thereof.

9. The sheet-form composite of claim 1 wherein the exudate transport layer comprises a hydrophilic pressure sensitive adhesive applied to at least a portion of the film layer in a discontinuous pattern.

10. The sheet-form composite of claim 1 wherein the film layer is a segmented polyurethane-urea polymer and the exudate transport layer is a hydrocolloid.

11. The sheet-form composite of claim 1 wherein the film layer is a segmented polyurethane-urea polymer and the exudate transport layer is a gel containing, on a weight percent basis of the gel, about 1% to about 99% water.

12. The sheet-form composite of claim 1 wherein the film layer is a segmented polyurethane-urea polymer and the exudate transport layer is a foam.

13. The sheet-form composite of claim 1 wherein the film layer is a segmented polyurethane-urea polymer and the exudate transport layer is a textile selected from the group consisting of a woven textile, a nonwoven textile, and combinations thereof.

14. The sheet-form composite of claim 1 wherein the film layer is a segmented polyurethane-urea polymer and the exudate transport layer is a polyurethane-based membrane having a controlled pore size.

15. The sheet-form composite of claim 1 further including medicaments in the exudate transport layer.

16. The sheet-form composite of claim 1 contained in a sterile package.

17. The sheet-form composite of claim 1 wherein the wound contacting face of the exudate transport layer is adhesive.

18. The sheet-form composite of claim 1 further including a releasable liner applied to the adhesive.

19. The sheet-form composite of claim 1 wherein moisture vapor transmission from said composite is initiated after a lag time in the range of about 30 minutes to about 150 minutes.

20. A method of protecting a wound which comprises applying the spyrosorbent dressing of claim 1 to said wound.