Method for conducting an ultrasound procedure using an ultrasound transmissive pad

• US 5,655,539 A
• Filed: 02/26/1996
• Issued: 08/12/1997
• Est. Priority Date: 02/26/1996
• Status: Expired due to Term

• Current Assignee: Abbott Laboratories
• Original Assignee: Abbott Laboratories
• Inventors: Wang, Jianjun, Bouska, Annette G., Drayer, Lonnie R.
• Primary Examiner(s): JAWORSKI, FRANCIS J
• Application Number:
  US08/606,877
• Time in Patent Office: 533 Days
• Field of Search: 128/663.01, 128/662.03, 604/892.1, 73/644
• US Class Current: 600/472
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61M 37/0092 using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
• CPC Class Codes: G10K 11/18 Methods or devices for transmitting, conducting or directing sound G10K11/02, G10K11/36 take precedence

Abstract

A method for conducting an ultrasound procedure on an object having a target surface. The method includes the step of providing an ultrasound probe having an acoustical wave emitting end portion. A pad for transmitting acoustical waves between the ultrasound probe and a target surface of an object also is provided. The pad includes a first layer having a first porous portion which defines first layer pores therethrough. The first layer pores have a first layer pore dimension. The pad further includes a second layer having a first porous portion which defines second layer pores therethrough. The second layer pores have a second layer pore dimension. The second layer is attached to the first layer so as to define a space therebetween. The first porous portion of the first layer overlies the first porous portion of the layer. An ultrasound couplant is disposed in the space defined between the first layer and the second layer. The ultrasound couplant has a molecule size which is less than or substantially equal to the first layer pore dimension, and which is less than or substantially equal to the second layer pore dimension. The method further includes the steps of placing the first porous portion of the second layer in contact with a target surface and placing the acoustical wave emitting end portion of the ultrasound probe in contact with the first porous portion of the first layer. The ultrasound probe is then activated.

Claims

1. A method for conducting an ultrasound procedure on an object having a target surface, said method comprising the steps of:

providing an ultrasound probe having an acoustical wave emitting end portion;

providing a pad for transmitting acoustical waves between said ultrasound probe and a target surface of an object, said pad comprising;

a first layer having a first porous portion, said first porous portion defining first layer pores therethrough, said first layer pores having a first layer pore dimension;

a second layer having a first porous portion, said first porous portion defining second layer pores therethrough, said second layer attached to said first layer, said first and second layers defining a space therebetween, said second layer pores having a second layer pore dimension, said first porous portion of said first layer overlying said first porous portion of said second layer; and

an ultrasound couplant disposed in said space defined between said first layer and said second layer, said ultrasound couplant having a molecule size, said molecule size being less than or substantially equal to said first layer pore dimension, and said molecule size being less than or substantially equal to said second layer pore dimension, whereby said ultrasound couplant becomes entrained in or passes through said first porous portions of said first and second layers, and whereby acoustical waves can be transmitted from said first layer to said second layer;

placing said first porous portion of said second layer in contact with a target surface;

placing said acoustical wave emitting end portion of said ultrasound probe in contact with said first porous portion of said first layer; and

activating said ultrasound probe whereby acoustical waves are emitted from said acoustical wave emitting end portion of said ultrasound probe, thereby directing acoustical waves to said target surface.

2. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 1, wherein said second layer pore dimension is greater than said molecule size of said ultrasound couplant and wherein said ultrasound couplant comprises a medical product.

3. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 2, wherein said medical product is selected from a group consisting of pharmaceuticals and imaging agents.

4. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 1, wherein said method further comprises the steps of providing a means for selectively activating said ultrasound probe, and coupling said means for selectively activating said ultrasound probe to said ultrasound probe.

5. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 4, wherein said means for selectively activating said ultrasound probe has a programmable energy level, and wherein said method further comprises the step of programming said means for selectively activating said ultrasound probe to a selected energy level.

6. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 4, wherein said means for selectively activating said ultrasound probe has a programmable frequency, and wherein said method further comprises the step of programming said means for selectively activating said ultrasound probe to a selected frequency.

7. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 4, wherein said means for selectively activating said ultrasound probe has a programmable duration for activation of said ultrasound probe, and wherein said method further comprises the step of programming said means for selectively activating said ultrasound probe to a selected duration for activation of said ultrasound probe.

8. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 4, wherein said means for selectively activating said ultrasound probe has a programmable delay period, and wherein said method further comprises the step of programming said means for selectively activating said ultrasound probe to a selected delay period.

9. A method for delivering a medical product to a target body tissue, said method comprising the steps of:

providing an ultrasound probe having an acoustical wave emitting end portion;

providing a pad for transmitting acoustical waves between said ultrasound probe and a surface of a target body tissue, said pad comprising;

a first layer having a first porous portion, said first porous portion defining first layer pores therethrough, said first layer pores having a first layer pore dimension;

a second layer having a first porous portion, said first porous portion defining second layer pores therethrough, said second layer attached to said first layer, said first and second layers defining a space therebetween, said second layer pores having a second layer pore dimension, said first porous portion of said first layer overlying said first porous portion of said second layer; and

an ultrasound couplant disposed in said space defined between said first layer and said second layer, said ultrasound couplant comprising a medical product, said ultrasound couplant having a molecule size, said molecule size being less than or substantially equal to said first layer pore dimension, and said molecule size being less than said second layer pore dimension, whereby said ultrasound couplant becomes entrained in or passes through said first porous portion of said first layer, whereby said ultrasound couplant passes through said first porous portion of said second layer, and whereby acoustical waves can be transmitted from said first layer to said second layer;

placing said first porous portion of said second layer in contact with a surface of a target body tissue;

placing said acoustical wave emitting end portion of said ultrasound probe in contact with said first porous portion of said first layer; and

activating said ultrasound probe whereby acoustical waves are emitted from said acoustical wave emitting end portion of said ultrasound probe, and whereby said acoustical waves disrupt said surface of a target body tissue, thereby facilitating delivery of said couplant to the target body tissue.

10. A method for delivering a medical product to a target body tissue in accordance with claim 9, wherein said medical product is selected from a group consisting of pharmaceuticals and imaging agents.

11. A method for delivering a medical product to a target body tissue, said method comprising the steps of:

providing an ultrasound probe having an acoustical wave emitting end portion;

providing a pad for transmitting acoustical waves between said ultrasound probe and a surface of a target body tissue, said pad comprising;

a first layer having a first porous portion, said first porous portion defining first layer pores therethrough, said first layer pores having a first layer pore dimension;

a second layer having a first porous portion, said first porous portion defining second layer pores therethrough, said second layer attached to said first layer, said first and second layers defining a space therebetween, said second layer pores having a second layer pore dimension, said first porous portion of said first layer overlying said first porous portion of said second layer; and

an ultrasound couplant disposed in said space defined between said first layer and said second layer, said ultrasound couplant having a molecule size, said molecule size being less than or substantially equal to said first layer pore dimension, and said molecule size being less than or substantially equal to said second layer pore dimension, whereby said ultrasound couplant becomes entrained in or passes through said first porous portions of said first and second layers, and whereby acoustical waves can be transmitted from said first layer to said second layer;

placing a medical product in contact with a surface of a target body tissue;

placing said first porous portion of said second layer in contact with said medical product;

placing said acoustical wave emitting end portion of said ultrasound probe in contact with said first porous portion of said first layer; and

activating said ultrasound probe, whereby acoustical waves are emitted from said acoustical wave emitting end portion of said ultrasound probe, and whereby said acoustical waves disrupt said surface of a target body tissue, thereby facilitating delivery of said medical product to the target body tissue.

12. A method for delivering a medical product to a target body tissue in accordance with claim 11, wherein said medical product is selected from a group consisting of pharmaceuticals and imaging agents.

13. A method for conducting an ultrasound procedure on an object having a target surface, said method comprising the steps of:

providing an ultrasound probe having an acoustical wave emitting end portion;

providing a pad for transmitting acoustical waves between said ultrasound probe and a target surface of an object, said pad comprising;

a first layer having a first porous portion, said first porous portion defining first layer pores therethrough, said first layer pores having a first layer pore dimension;

a second layer having at least one aperture formed therethrough, said at least one aperture having an aperture dimension, said second layer attached to said first layer, said first and second layers defining a space therebetween, said first porous portion of said first layer overlying said at least one aperture formed through said second layer; and

an ultrasound couplant disposed in said space defined between said first layer and said second layer, said ultrasound couplant having a molecule size, said molecule size being less than or substantially equal to said first layer pore dimension, and said molecule size being less than or substantially equal to said aperture dimension, whereby said ultrasound couplant becomes entrained in or passes through said first porous portion of said first layer, whereby said ultrasound couplant becomes entrained in or passes through said at least one aperture formed through said second layer, and whereby acoustical waves can be transmitted from said first layer to said second layer;

placing said at least one aperture formed through said second layer in contact with a target surface;

placing said acoustical wave emitting end portion of said ultrasound probe in contact with said first porous portion of said first layer; and

activating said ultrasound probe whereby acoustical waves are emitted from said acoustical wave emitting end portion of said ultrasound probe.

14. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 13, wherein said ultrasound couplant comprises a medical product.

15. A method for conducting an ultrasound procedure on an object having a target surface in accordance with claim 14, wherein said medical product is selected from a group consisting of pharmaceuticals and imaging agents.