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Ionosonic drug delivery apparatus

  • US 5,658,247 A
  • Filed: 06/06/1995
  • Issued: 08/19/1997
  • Est. Priority Date: 04/07/1993
  • Status: Expired due to Fees
First Claim
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1. An iontophoretic transdermal drug delivery device adapted to releasably attach to a person'"'"'s body so that a skin-contacting surface of said device is adjacent to a portion of the person'"'"'s skin, said device having electrical connection means thereon adapted to electrically connect said device to a multiplicity of current sources, said device being operable for iontophoretically driving a medicament across said skin-contacting surface of said device into said portion of the person'"'"'s skin, said device further comprising, in combination:

  • (a) a medicament carrying layer in fluid communication with said skin-contacting surface of said device comprising a porous sheet impregnated with a medicament containing fluid;

    (b) an iontophoresis electrode in electrical communication with said medicament carrying layer providing means for iontophoretically driving said medicament into the person'"'"'s skin, said iontophoresis electrode further comprising a plurality of electrode channels, each electrode channel of said plurality of electrode channels being electrically isolated from other electrode channels comprising said plurality electrode channels, said plurality of electrode channels having electrical connection means connected thereto adapted for simultaneous electrical connection of selected electrode channels to the same or different current sources, said each electrode channel being in electrical communication with said medicament carrying layer; and

    (c) a plurality of piezoelectric elements affixed to a flexible plastic sheet affixed to and overlying said iontophoresis electrode.

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