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Method for rapid temporal control of molecular transport across tissue

  • US 5,667,491 A
  • Filed: 06/07/1995
  • Issued: 09/16/1997
  • Est. Priority Date: 01/21/1988
  • Status: Expired due to Fees
First Claim
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1. A method for transdermally treating an organism in response to an intrinsic condition, comprising the steps of:

  • a) applying a medication to epidermis of the organism;

    b) electroporating the epidermis at a first voltage pulse condition in response to said intrinsic condition to initiate delivery of the medication through the epidermis; and

    c) electroporating said epidermis at a second voltage pulse condition, whereby the medication continues to pass through the epidermis at a rate sufficient to alter the intrinsic condition, thereby rapidly treating the organism.

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