Compositions for use in embolizing blood vessels
First Claim
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1. A composition comprising:
- (a) from about 2.5 to about 8.0 weight percent of an ethylene vinyl alcohol copolymer;
(b) from about 10 to about 40 weight percent of a water insoluble contrast agent selected from the group consisting of tantalum, tantalum oxide and barium sulfate;
(c) from about 52 to about 87.5 weight percent of a biocompatible solventwherein the weight percent of each of the components is based on the total weight of the complete composition.
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Abstract
Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise an ethylene vinyl alcohol copolymer, a biocompatible solvent and a water insoluble contrasting agent selected from the group consisting of tantalum, tantalum oxide and barium sulfate. Also disclosed are methods for embolizing a blood vessel using the compositions described herein.
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Citations
15 Claims
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1. A composition comprising:
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(a) from about 2.5 to about 8.0 weight percent of an ethylene vinyl alcohol copolymer; (b) from about 10 to about 40 weight percent of a water insoluble contrast agent selected from the group consisting of tantalum, tantalum oxide and barium sulfate; (c) from about 52 to about 87.5 weight percent of a biocompatible solvent wherein the weight percent of each of the components is based on the total weight of the complete composition. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for embolizing a blood vessel by injecting into said blood vessel a sufficient amount of an embolizing composition comprising:
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(a) from about 2.5 to about 8.0 weight percent of an ethylene vinyl alcohol copolymer embolizing agent; (b) from about 10 to about 40 weight percent of a water insoluble contrast agent selected from the group consisting of tantalum, tantalum oxide and barium sulfate; (c) from about 52 to about 87.5 weight percent of a biocompatible solvent wherein the weight percent of each of the components is based on the total weight of the complete composition under conditions wherein a precipitate is formed which embolizes the blood vessel. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15)
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Specification