Method and apparatus for proton therapy

• US 5,668,371 A
• Filed: 10/01/1996
• Issued: 09/16/1997
• Est. Priority Date: 06/06/1995
• Status: Expired due to Term

• Current Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Original Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Inventors: Deasy, Joseph O., DeLuca, Paul M. Jr., Mackie, Thomas R.
• Primary Examiner(s): ANDERSON, BRUCE C
• Application Number:
  US08/722,727
• Time in Patent Office: 350 Days
• Field of Search: 250/306, 250/505.1, 250/307
• US Class Current: 850/1
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1095 Elements inserted into the radiation path within the system, e.g. filters or wedges
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: G21K 1/046 varying the contour of the field, e.g. multileaf collimators

Abstract

A method of proton tomotherapy provides uniform dose placement within a tumorous area on a slice by slice basis by locating a Bragg peak of the proton beam at the distal edge of the tumor and irradiating the tumor from a number of different angles without sweeping the range of the protons at the given angle. Uniform dose is provided by simultaneous intensity modulation of the beams. Treatment of the tumor in slices eliminates the need for a rotating gantry but allows the patient to be rotated instead. Accurate range placement is provided by a preliminary proton verification tomogram obtainable on the same equipment. A set of standard blocks permits this technique to be used with standard irradiation zones without additional range or intensity adjusting mechanism.

Claims

1. In a proton therapy machine having a proton source for producing a proton beam directed toward a patient at a gantry angle, the beam including a plurality of adjacent rays dispersed within a beam plane, a modulator comprising:

an intensity control means for independently controlling the fluence of the protons along each of the rays; and

a range shifting means for independently controlling the distance the protons travel through the patient along each of the rays.

2. The modulator as recited in claim 1 wherein the intensity control means includes:

a plurality of fluence leaves moving within a rack positioned generally between the radiation source and the patient and guiding the fluence leaves between a closed state within the proton beam where each fluence leaf blocks the protons along one ray, and an open state where each fluence leaf permits passage of protons along one ray;

an actuator moving the fluence leaves between the open and closed state; and

a timer communication with the actuator to control the ratio of the period of time during which each fluence leaf is in the closed state to the period during which each fluence leaf is in the open state to control the average energy fluence of the protons along each ray.

3. The modulator as recited in claim 1 wherein the intensity control means includes:

a plurality of fluence leaves moving within a rack positioned generally between the radiation source and the patient where the position of each leaf controls the scattering of protons traveling along a corresponding ray;

an actuator moving the leaves within the rack; and

a collimator for blocking from the patient the protons scattered by the fluence leaves.

4. The modulator as recited in claim 1 wherein the range shifting means includes:

a plurality of range leaves moving within a rack positioned generally between the radiation source and the patient where the position of each range leaf controls the range of proton travel in the patient along a corresponding ray; and

an actuator moving the range leaves within the rack.

5. The modulator as recited in claim 4 wherein the range leaves are wedge shaped blocks of material so that movements of each range leaf changes the thickness of the material through which protons travel.