Method and apparatus for inducing the permeation of medication into internal tissue
First Claim
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1. A method for selectively inducing the permeation of liquid to a targeted portion of internal tissue in the body of a patient comprising the steps of:
- generating a polar electric field in which one pole of the field is disposed in a first position relative to the targeted portion of the tissue and the return pole is disposed in a second position relative to the targeted portion of the tissue;
supplying liquid having polar molecules to a location in the body adjacent the targeted portion of the tissue;
said electric field being polarized with respect to the polarization of the polar molecules such that the electric field will induce flow of the polar molecules through the targeted portion of the internal tissue toward the other pole of the field.
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Abstract
A method and apparatus for selectively treating a targeted portion of internal body tissue of a patient by providing an internal electrode at a point adjacent the tissue to be treated and electrodes external to the patient'"'"'s body. Fluid containing Ionic molecules is supplied to a location between the internal electrode and the external electrodes and an electric field radiating outwardly from the internal electrode to the external electrodes is created so that said fluid flows outwardly away from said internal electrode into the tissue to be treated.
100 Citations
15 Claims
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1. A method for selectively inducing the permeation of liquid to a targeted portion of internal tissue in the body of a patient comprising the steps of:
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generating a polar electric field in which one pole of the field is disposed in a first position relative to the targeted portion of the tissue and the return pole is disposed in a second position relative to the targeted portion of the tissue; supplying liquid having polar molecules to a location in the body adjacent the targeted portion of the tissue; said electric field being polarized with respect to the polarization of the polar molecules such that the electric field will induce flow of the polar molecules through the targeted portion of the internal tissue toward the other pole of the field. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for inducing the permeation of a liquid having charged molecules into a blood vessel comprising the steps of:
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providing a first electrode inserting percutaneously into a blood vessel a balloon catheter having an elongate flexible shaft, with a porous balloon at the distal end of said shaft, and a second electrode being positioned inside said balloon on said elongated flexible shaft, inflating said balloon with said liquid; and developing an electric field flowing from said second electrode to said first electrode so that liquid flows radially outward through said pores in said balloon to the blood vessel to be treated.
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12. A method for inducing the permeation of a fluid having charged molecules into internal tissue comprising the steps of:
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providing a first electrode; inserting a balloon catheter having an elongate flexible shaft, with a porous balloon at the distal end of said shaft, and a second electrode being positioned inside said balloon on said elongate flexible shaft, inflating said balloon with said fluid; and developing an electric field flowing from said second electrode to said first electrode so that said fluid flows radially outward through said pores in said balloon to said tissue to be treated.
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13. A method for selectively inducing the permeation of liquid to a targeted portion of internal tissue in the body of a patient comprising the steps of:
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generating a polar electric field in which at least one pole of the field is disposed internally of the targeted portion of the tissue; supplying liquid having polar molecules to a location in the body adjacent the targeted portion of the tissue; said electric field being polarized with respect to the polarization of the polar molecules such that the electric field will induce flow of the polar molecules through the targeted portion of the internal tissue.
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14. A method for inducing the permeation of a fluid having charged molecules into internal tissue comprising the steps of:
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inserting a balloon catheter having an elongate flexible shaft, with a porous balloon at the distal end of said shaft, and an electrode being positioned in the area of said balloon on said elongate flexible shaft; inflating said balloon with said fluid; and developing an electric field so that said fluid flows radially outward through said pores in said balloon to said tissue to be treated.
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15. A method for inducing the permeation of a liquid having charged molecules into a blood vessel comprising the steps of:
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inserting percutaneously into a blood vessel a balloon catheter having an elongate flexible shaft, with a porous balloon at the distal end of said shaft, and an electrode being positioned in proximity to said balloon on said elongated flexible shaft, inflating said balloon with said liquid; and developing an electric field so that liquid flows radially outward through said pores in said balloon to the blood vessel to be treated.
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Specification