Endovascular embolic device detachment detection method and apparatus

• US 5,669,905 A
• Filed: 07/11/1995
• Issued: 09/23/1997
• Est. Priority Date: 03/03/1994
• Status: Expired due to Term

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Target Therapeutics, Inc. (Boston Scientific Corporation)
• Inventors: Schaller, Laurent B., Scheldrup, Ronald W.
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): HUANG, STEPHEN D
• Application Number:
  US08/481,453
• Time in Patent Office: 805 Days
• Field of Search: 604/286, 606/32, 606/191, 606/200, 606/41, 128/630
• US Class Current: 606/32
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/00123 and automatic shutdown
• CPC Class Codes: A61B 2017/12063 electrolytically detachable

Abstract

This invention is a method for ensuring for endovascular occlusion through the formation of thrombi in arteries, veins, aneurysms, vascular malformations, and arteriovenous fistulas. In particular, it deals with a method to predictably determine the instant of electrolytic detachment of an embolic device which is introduced to and is intended to remain at the desired thrombus formation site. The invention further includes a method for delivering an embolic device and detecting its electrolytic separation. According to the present invention, DC power with AC superposition is delivered to the sacrificial link that couples a delivery member (e.g., a guidewire) to an occlusion device. The impedance (as measured by the amplitude of the superposed AC) is monitored. When a predetermined change in that impedance (or amplitude occurs), which indicates coil detachment, the DC power is interrupted to minimize or avoid further electrolysis.

Claims

1. An implant detachment detection system comprising:

an implant suitable for implanting in a mammal;

a delivery member for delivering the implant to a selected site in the mammal;

a link coupling said delivery member to said implant;

a power supply circuit for supplying DC power with AC power superposed thereon;

a conductive path, said power supply circuit and link being in said path; and

an AC impedance monitoring circuit coupled to said path.

2. The system of claim 1 wherein said monitoring circuit detects changes in the monitored impedance.

3. The system of claim 2 further including an interrupting circuit that interrupts the DC power to the link when a predetermined change in impedance is detected.

4. The system of claim 2 wherein said monitoring circuit generates said signal in response to detection of at least about a 20% change in the AC impedance of said path.

5. The system of claim 2 wherein said monitoring circuit generates a signal indicative of the implant becoming decoupled from said delivery member in response to detecting a predetermined change in impedance.

6. The system of claim 1 further including a circuit for interrupting the DC power supply to the link in response to a sudden change in the monitored impedance.

7. The system of claim 1 wherein said power supply circuit comprises a generator that provides said DC power with superposed AC.

8. The system of claim 1 wherein said power supply circuit comprises a DC power generator and an AC signal generator coupled to said DC generator.

9. The system of claim 1 further including a return electrode in said path, said power supply circuit being located between said link and return electrode in said path and said AC impedance monitoring circuit being coupled to said path between said power supply and link.

10. The system of claim 1 further including a return electrode in said path, said power supply circuit being located between said link and return electrode in said path and said AC impedance monitoring circuit being coupled to said path between said power supply and said return electrode.

11. The system of claim 1 wherein said implant comprises an embolic coil.

12. An implant detachment detection system comprising:

an implant suitable for implantation in a mammal;

a delivery member for delivering the implant to a selected site in the mammal;

a link coupling said delivery member to said implant;

means for providing direct and superposed alternating current to said link; and

means for monitoring the alternating current provided by said providing means.

13. The system of claim 12 further including means for interrupting direct current supplied to said link when a predetermined change in the superposed alternating current is detected.

14. An implant detachment system comprising:

an implant adapted for placement in a mammal;

a delivery member for delivering the implant to a selected site in the mammal;

a link for coupling said delivery member to said implant; and

a power supply circuit for supplying direct and superposed alternating current to said link concurrently when said implant is at said selected site.

15. The system of claim 14 further comprising a circuit for monitoring alternating current supplied to said link.

16. The system of claim 15 wherein said circuit is adapted for coupling to said mammal when said implant is at said site.

17. The system of claim 14 further comprising a circuit for monitoring alternating current supplied to said link and detecting a change therein.

18. The system of claim 14 further comprising a circuit for isolating alternating current supplied to said link from the direct current supplied to said link so that AC may be monitored.

19. An implant detachment detection system comprising:

an implant adapted for placement in a mammal;

a delivery member for delivering the implant to a selected site in the mammal;

a link detachably coupling said delivery member to said implant; and

a power supply circuit for supplying direct and superposed alternating current to said link when said implant is at said selected site.

20. The system of claim 19 further including a circuit for monitoring alternating current supplied to said link.

21. The system of claim 19 wherein said power supply circuit is configured for supplying direct and superposed alternating current to said link.

22. The system of claim 19 further including a circuit for isolating alternating current supplied to said link from direct current supplied to said link.