Controlled release osmotic pump
First Claim
1. A pump comprising:
- a. a first pouch containing a liquid to be pumped and having an outlet;
b. a second pouch in pressure transmitting relationship to said first pouch;
c. an integral power source comprising;
a pressure generating means for generating pressure in said second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when the liquid permeant contacts the osmagent;
d. a housing containing said first and second pouches said housing being in restraining relationship to the aforesaid first and second pouch;
e. an activating means for initiating the action of said pressure generating means comprising;
a flexible tube fluidly coupling the liquid permeant which is to contact the osmagent with a semipermeable membrane when the flexible tube is in an open condition; and
means for selectively retaining the tube in a closed condition thereby fluidly isolating the liquid permeant from the semipermeable membrane.
6 Assignments
0 Petitions
Accused Products
Abstract
A portable osmotic pump, having two pouches (4,3) in pressure-transmitting relationship, the first (4) containing a pumped fluid, such as infusate (5), and the second (3), a driving fluid (36). The driving fluid is created and pressurized by activation of an osmotic pump, and the rate of infusion is controlled by a semipermeable membrane (10). Activation can be by rupturing a seal (11) or by opening a closed tube (58) to permit permeant (2) to contact the semipermeable membrane. Pulses of the pumped fluid can be achieved by delivery pulses of the permeant to the second pouch. The pouches can be designed to resist collapse of the first pouch by external forces on the pumped liquid, such as gravity, movement of the first pouch and negative pressures applied to the pumped liquid. The infusate pouch is manufactured separately and can be stored apart from the rest of the system.
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Citations
25 Claims
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1. A pump comprising:
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a. a first pouch containing a liquid to be pumped and having an outlet; b. a second pouch in pressure transmitting relationship to said first pouch; c. an integral power source comprising; a pressure generating means for generating pressure in said second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when the liquid permeant contacts the osmagent; d. a housing containing said first and second pouches said housing being in restraining relationship to the aforesaid first and second pouch; e. an activating means for initiating the action of said pressure generating means comprising; a flexible tube fluidly coupling the liquid permeant which is to contact the osmagent with a semipermeable membrane when the flexible tube is in an open condition; and means for selectively retaining the tube in a closed condition thereby fluidly isolating the liquid permeant from the semipermeable membrane. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A pump comprising:
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a. a first pouch containing a liquid to be pumped and having an outlet; b. a second pouch in pressure transmitting relationship to said first pouch; c. an integral power source comprising; a pressure generating means for generating pressure in said second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when the liquid permeant contacts the osmagent; an activating means for initiating the action of said pressure generating means; a rate-controlling means for regulating the volume change of said first pouch comprising a semipermeable membrane; d. a housing containing said first and second pouches and in restraining relationship to the aforesaid first and second pouch and e. means for temporarily increasing the flow of liquid permeant to the second pouch to react with the osmagent in the second pouch to produce a temporary pulse of driving fluid in the second pouch to transmit pressure to the first pouch so as to deliver a temporarily increased flow of the pumped liquid through the outlet of the first pouch. - View Dependent Claims (15, 16, 17)
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18. A pump comprising:
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a. a first pouch containing a liquid to be pumped and having an outlet; b. a second pouch in pressure transmitting relationship to said first pouch; c. an integral power source comprising; a pressure generating means for generating pressure in said second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when the liquid permeant contacts the osmagent; an activating means for initiating the action of said pressure generating means; a rate-controlling means comprising a semi-permeable membrane for regulating the volume change of said first pouch; and d. a housing containing said first and second pouches and in restraining relationship to the aforesaid first and second pouch; and e. said first and second pouches having means for forcing engagement between the first and second pouches for assisting the first pouch to resist collapsing when subjected to at least one of the following forces selected from the group consisting of; a negative pressure applied to the outlet, a gravity force applied to the first pouch and a force due to movement of the first pouch. - View Dependent Claims (19, 20, 21)
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22. A pump comprising:
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a. a first pouch having an outlet and containing a liquid to be pumped through said outlet; b. a second pouch in pressure-transmitting relationship to said first pouch; c. an integral power source comprising; a pressure generating means for generating pressure in said second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when the liquid permeant contacts osmagent; an activating means for initiating the action of said pressure generating means; a rate-controlling means for regulating the volume change of said first pouch, comprising a semipermeable membrane; d. means for temporarily increasing the flow of liquid permeant to the second pouch to react with the osmagent in the second pouch to produce a temporary pulse of driving fluid in the second pouch to transmit pressure to the first pouch to deliver a temporarily increased flow of the liquid pumped through said first pouch outlet; and e. means for applying a force to the first pouch for assisting the first pouch to resist collapsing when subjected to at least one of the following forces selected from the group consisting of; a negative pressure applied to the outlet, a gravity force applied to the first pouch and a force due to movement of the first pouch.
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23. A method for pumping a liquid to a receiver, comprising connecting said receiver to a pump, said pump comprising:
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a. a first pouch having an outlet and containing the liquid to be pumped; b. a second pouch in pressure-transmitting relationship to said first pouch; c. an integral power source comprising; a pressure generating means for generating pressure in said second pouch, comprised of an osmagent and a liquid permeant, wherein a driving fluid is produced when the liquid permeant contacts osmagent; an activating means for initiating the action of said pressure generating means; a rate-controlling means for regulating the volume change of said first pouch, comprising a semipermeable membrane; d. a housing containing said first and second pouches and in restraining relationship to said first and second pouches; and e. a pump for delivering a temporary pulse of the liquid permeant to the second pouch to react with the osmagent to produce a temporary pulse of the driving fluid in the second pouch so to deliver a pulse of the liquid pumped through the first pouch outlet. - View Dependent Claims (24, 25)
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Specification