Coregistration of multi-modality data in a medical imaging system

• US 5,672,877 A
• Filed: 03/27/1996
• Issued: 09/30/1997
• Est. Priority Date: 03/27/1996
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Adam Laboratories Inc.
• Inventors: Jones, Steven M., Wang, Xiaohan, Liebig, John R.
• Primary Examiner(s): FIELDS, CAROLYN
• Application Number:
  US08/623,908
• Time in Patent Office: 552 Days
• Field of Search: 378/63, 378/162, 250/363.04
• US Class Current: 250/363.04
• CPC Class Codes: A61B 6/037 Emission tomography
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61B 6/5247 combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
• CPC Class Codes: G01T 1/1648 Ancillary equipment for scintillation cameras, e.g. reference markers, devices for removing motion artifacts, calibration devices adapted for flow studies G01T1/1647

Abstract

A method of coregistering medical image data of different modalities is provided. In the method, an emission scan of an object is performed using a nuclear medicine imaging system to acquire single-photon emission computed tomography (SPECT) image data. A transmission scan of the object is performed simultaneously with the emission scan using the same nuclear medicine imaging system in order to acquire nuclear medicine transmission image data. The emission scan is performed using a roving zoom window, while the transmission scan is performed using the full field of view of the detectors. By knowing the position of the zoom windows for each detection angle, the nuclear medicine transmission image data can be coregistered with the SPECT emission image data as a result of the simultaneous scans. Image data of a modality other than SPECT, such as x-ray computed tomography (x-ray CT) data, magnetic resonance imaging (MRI) data, or positron emission tomography (PET) data, is also provided, which it is desired to have coregistered with the SPECT emission data. The nuclear medicine transmission image data is therefore coregistered with the image data of the different modality. As a result, the image data of the different modality becomes coregistered with the SPECT image data.

Claims

1. A method of coregistering medical image data of different modalities, the method comprising the steps of:

performing an emission scan of an object using a nuclear medicine imaging system to acquire single-photon emission computed tomography (SPECT) image data;

performing a transmission scan of the object using the nuclear medicine imaging system to acquire nuclear medicine transmission image data that is coregistered with the SPECT image data;

providing image data of a third modality, wherein the third modality is a modality other than SPECT or nuclear medicine transmission imaging; and

coregistering the nuclear medicine transmission image data with the image data of the third modality, such that the image data of the third modality becomes coregistered with the SPECT image data.

2. A method according to claim 1, wherein the step of performing the transmission scan is performed simultaneously with the step of performing the emission scan.

3. A method according to claim 2, wherein a plurality of position values correspond to the nuclear medicine transmission image data, and wherein the step of coregistering the nuclear medicine transmission image data and the SPECT image data comprises the steps of:

determining a plurality of offset values representing spatial offsets between elements of the SPECT image data and corresponding elements of the nuclear medicine transmission image data; and

adjusting the position values associated with the nuclear medicine transmission image data based on the offset values.

4. A method according to claim 1, wherein the method is implemented in a computer system.

5. A method according to claim 4, wherein the computer system comprises a display device and an input device, and wherein the step of coregistering comprises the steps of:

displaying a first image on the display device based on the nuclear medicine transmission image data;

displaying a second image on the display device based on the image data of the third modality; and

accepting a set of user inputs from the input device, the user inputs for manually repositioning the second image relative to the first image; and

outputting a third image based on the SPECT image data positioned according to the set of user inputs.

6. A method according to claim 4, wherein the computer system comprises a processor, and wherein the method further comprises the step of configuring the processor to coregister the set of nuclear medicine transmission image data with the image data Of the third modality, to coregister the SPECT image data with the image data of the third modality.

7. A method according to claim 6, wherein the step of coregistering comprises the step of using the processor to automatically coregister the SPECT image data and the image data of the third modality.

8. In a nuclear medicine imaging system having a detector for receiving radiation and outputting image information, a radiation source for transmitting radiation through an object to a scintillation detector, and a computer system;

a computer-implemented method of coregistering medical image data of a plurality of modalities, the method comprising the steps of;

controlling the scintillation detector and the radiation source to simultaneously perform an emission scan of the object to acquire a set of single-photon emission computed tomography (SPECT) image data and a transmission scan of the object to acquire a set of nuclear medicine transmission image data;

coregistering the SPECT data and the nuclear medicine transmission image data;

inputting into the computer system a third set of image data, wherein the third set of image data is of a modality other than SPECT or nuclear medicine transmission imaging; and

coregistering the set of nuclear medicine transmission image data with the third set of image data to cause the third set of image data to be coregistered with the SPECT image data.

9. A method according to claim 8, wherein the nuclear medicine transmission image data includes a plurality of position values, and wherein the step of coregistering the nuclear medicine transmission image data and the SPECT image data comprises the steps of:

determining a plurality of offset values representing spatial offsets between elements of the SPECT image data and corresponding elements of the nuclear medicine transmission image data; and

adjusting the position values based on the offset values.

10. A method according to claim 8, wherein the computer system comprises a display device and an input device, and wherein the step of coregistering the set of nuclear medicine transmission image data with the third set of image data comprises the steps of:

displaying a first image on the display device based on the nuclear medicine transmission image data;

displaying a second image on the display device based on the third set of image data; and

accepting a set of user inputs from the input device, the user inputs specifying a change in the relative positioning of the first image and the second image as displayed on the display device; and

displaying a third image on the display device based on the SPECT image data, such that the third image is displayed in a position determined according to the set of user inputs.

11. A method according to claim 8, wherein the computer system includes a processor, and wherein the method further comprises the step of configuring the processor to automatically coregister the set of nuclear medicine transmission image data with the third set of image data in response to a user input.

12. A method according to claim 8, wherein the step of coregistering comprises the step of using the processor to automatically coregister the SPECT image data and the third set of image data.

13. An apparatus for coregistering medical image data of different modalities, comprising:

means for performing an emission scan of an object using a nuclear medicine imaging system to acquire single-photon emission computed tomography (SPECT) image data;

means for performing a transmission scan of the object using the nuclear medicine imaging system to acquire nuclear medicine transmission image data that is coregistered with the SPECT image data;

means for providing image data of a third modality other than SPECT or nuclear medicine transmission imaging; and

means for coregistering the nuclear medicine transmission image data with the image data of the third modality, such that the image data of the third modality becomes coregistered with the SPECT image data.

14. An apparatus according to claim 13, wherein the means for performing the transmission scan comprises means for performing the transmission scan simultaneously with the emission scan.

15. An apparatus according to claim 14, wherein the nuclear medicine transmission image data is associated with a plurality of position values, and wherein the means for coregistering the nuclear medicine transmission image data and the SPECT image data comprises:

means for determining a plurality of offset values representing spatial offsets between elements of the SPECT image data and corresponding elements of the nuclear medicine transmission image data; and

means for adjusting the position values associated with the based on the offset values.

16. An apparatus according to claim 13, wherein the apparatus further comprises a computer system.

17. An apparatus according to claim 16, wherein the computer system comprises a display device and an input device, and wherein the means for coregistering comprises:

means for displaying a first image on the display device based on the nuclear medicine transmission image data;

means for displaying a second image on the display device based on the image data of the third modality; and

means for accepting a set of user inputs from the input device, the user inputs for manually repositioning the second image relative to the first image; and

means for outputting a third image based on the SPECT data in a position determined according to the set of user inputs.

18. An apparatus according to claim 16, wherein the computer system comprises means for automatically coregistering the set of nuclear medicine transmission image data with the image data of the third modality.

19. A nuclear medicine imaging system, comprising:

a detector for receiving radiation and outputting image information;

a radiation source for transmitting radiation through an object to the detector; and

a computer system coupled to the detector and the radiation source, the computer system including a processor configured to;

control the detector and the radiation source to simultaneously perform an emission scan of the object to acquire a set of single-photon emission computed tomography (SPECT) data and a transmission scan of the object to acquire a set of nuclear medicine transmission data;

coregister the SPECT data and the nuclear medicine transmission data;

input into the computer system a third set of image data of a modality other than SPECT or nuclear medicine transmission imaging; and

coregister the set of nuclear medicine transmission data with the third set of image data to cause the third set of image data to be coregistered with the SPECT data.

20. An imaging system according to claim 19, wherein the nuclear medicine transmission data includes a plurality of position values, and wherein the processor is configured to coregister the nuclear medicine transmission data and the SPECT data by:

determining a plurality of offset values representing spatial offsets between elements of the SPECT data and corresponding elements of the nuclear medicine transmission data; and

adjusting the position values based on the offset values.

21. An imaging system according to claim 20, wherein the computer system further comprises a display device and an input device, and wherein the processor is configured to coregister the set of nuclear medicine transmission data with the third set of image data by:

displaying a first image on the display device based on the nuclear medicine transmission data;

displaying a second image on the display device based on the third set of image data; and

accepting a set of user inputs from the input device, the user inputs specifying a change in the relative positioning of the first image and the second image as displayed on the display device; and

displaying, based on the user inputs and the SPECT data, a third image on the display device, such that the second image and the third image are displayed superimposed.

22. An imaging system according to claim 20, wherein the processor is further configured to automatically coregister the set of nuclear medicine transmission data with the third set of image data in response to a user input.