Cardiac pacemaker system and method for determining a measure of pacing threshold without incurring loss of capture

• US 5,674,254 A
• Filed: 05/22/1995
• Issued: 10/07/1997
• Est. Priority Date: 05/22/1995
• Status: Expired due to Fees

• Current Assignee: Vitatron Medical BV
• Original Assignee: Vitatron Medical BV
• Inventors: van Krieken, Frits M.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US08/445,667
• Time in Patent Office: 869 Days
• Field of Search: 607/28, 607/11, 607/9
• US Class Current: 607/11
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

A implantable cardiac pacemaker system which is battery powered, having an improved capability for monitoring patient threshold and adjusting pace pulse output to an optimized safety factor above patient threshold, thereby avoiding excessive energy expenditure in delivery of pace pulses and maximizing pacemaker lifetime. The improved threshold tracking system analyzes information from detected heart signals and correlates changes in such heart signal information to pulse output energy, enabling a determination of when the pulse output energy is near threshold without dropping below threshold. In a preferred embodiment, changes in the QT interval are monitored and correlated with changes in output pulse energy, enabling the pacemaker to obtain a measure of patient threshold without dropping pulse energy below threshold and suffering loss of capture.

Claims

1. An implantable cardiac pacemaker system, having a pacemaker and a lead for connecting signals between said pacemaker and a patient'"'"'s heart, the pacemaker having a controllable pulse generator for generating and delivering pace pulses at a controlled output level, sensing means for sensing evoked cardiac signals from said patient representative of cardiac activity in response to delivered pace pulses, control means for controlling the output level of said generated and delivered pace pulses, and a battery for providing energy, further comprising:

program means for programming said control means to vary said pace pulse output level in accordance with a predetermined program;

information means for collecting information from each of said sensed cardiac signals during said predetermined program;

storage means for storing data relating to changes in said evoked signals as a function of pace pulse output level; and

determining means for determining from said information and from said stored data a measure of patient threshold.

2. The pacemaker system as described in claim 1, wherein said storage means comprises a stored representation of prior actual patient threshold.

3. The pacemaker system as described in claim 2, wherein said storage system comprises stored data representative of prior determined values of QT and corresponding values of pace pulse output level.

4. The pacemaker system as described in claim 1, comprising means for updating said stored data.

5. The pacemaker system as described in claim 1, wherein said sensing means senses evoked T-waves, and said information means collects QT interval information.

6. The pacemaker system as described in claim 1, wherein said sensed signal information comprises data representative of evoked QRS wave morphology.

7. The pacemaker system as described in claim 1, wherein said sensed signal information comprises data representative of evoked T-wave morphology.

8. The pacemaker system as described in claim 1, wherein said sensed signals comprise T-waves, further comprising means for determining each QT interval corresponding to each said delivered pace pulse during said program, and said storage means comprises a stored value of a predetermined change in QT corresponding to a change from a predetermined high pace pulse output level to an output level near threshold.

9. The pacemaker system as described in claim 1, further comprising output adjust means for adjusting the output level of said pace pulses as a function of said threshold measure.

10. A pacemaker system for delivering pace pulses to a patient, said system having a pacemaker with a controllable pulse generator for generating pace pulses, control means for controlling the output level of said pace pulses, lead means for delivering pace pulses to the patient'"'"'s heart and detecting patient heart signals, sensing means for sensing selected signals from the patient'"'"'s heart, and energy source means for providing energy for said pacemaker, further comprising:

output program means for lowering the pace pulse output level in a predetermined manner, information means for obtaining information relating to each said sensed signal corresponding to a heartbeat evoked by a pace pulse of lowered level, and determining means for determining a measure of patient pacing threshold as a function of said information.

11. A pacemaker system as described in claim 10, wherein said information means comprises processing means for processing each said sensed signal in accordance with a first predetermined function to get processed data, and said determining means comprises means for determining said measure of patient threshold as a second function of said processed data.

12. The pacemaker system as described in claim 11, comprising storage means for storing information representative of the relation of said processed data to patient threshold.

13. The pacemaker system as described in claim 12, wherein said first function is QT interval, and wherein said storage means stores data representative of a critical change in QT interval corresponding to changed pace pulse output level.

14. A method for automatically obtaining a measure of patient threshold in an implantable pacemaker without dropping the output level of any delivered pace pulse below threshold, said pacemaker being powered by a battery and having a controllable pulse generator for generating and delivering pace pulses of controllable output level, comprising:

changing the output level of said pace pulses in accordance with a predetermined program;

sensing cardiac signals evoked by said pace pulses of changed output level and obtaining information from a predetermined portion of each said sensed signal; and

determining when said information indicates that pace pulse output level has been changed to a level above but critically close to patient threshold, said determined critical level being a measure of patient threshold.

15. The method as described in claim 14, comprising adjusting said pace pulse output level as a function of said determined critical level.

16. The method as described in claim 14, wherein said sensing comprises sensing evoked T-waves, and said determining comprises determining the pulse level at which the time from a delivered pace pulse to an evoked T-wave corresponds to a value still above, but near threshold.

17. An implantable cardiac pacemaker system, having a pacemaker and a lead for connecting signals between said pacemaker and a patient'"'"'s heart, the pacemaker having a controllable pulse generator for generating and delivering pace pulses at a controlled output level, sensing means for sensing evoked cardiac signals from said patient representative of cardiac activity in response to delivered pace pulses, control means for controlling the output level of said generated and delivered pace pulses, and a battery for providing energy, further comprising:

program means for programming said control means to vary said pace pulse output level in accordance with a predetermined program;

data means for collecting information relating to each Q-T interval following a pace pulse during said program,

storage means for storing data representative of change in Q-T interval corresponding to change in pace pulse output level from a predetermined level to a level above but near threshold, and

determining means for determining a measure of patient threshold as a function of said collected information and said stored data.