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Medicinal aerosol formulations

  • US 5,674,473 A
  • Filed: 05/31/1995
  • Issued: 10/07/1997
  • Est. Priority Date: 12/06/1988
  • Status: Expired due to Term
First Claim
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1. A method of making a solution aerosol formulation suitable for delivery to the lung by inhalation, comprising the steps of:

  • (a) providing an aerosol container, and(b) charging to said container;

    (i) a medicament in an amount sufficient to provide a plurality of therapeutically effective doses of said formulation,(ii) an amount of propellant sufficient to propel from said container said plurality of therapeutically effective doses, said propellant being substantially free of chlorofluorocarbons and comprising 1,1,1,2-tetrafluoroethane; and

    (c) solubilizing said medicament.

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