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Composition for sustained release of non-aggregated erythropoietin

  • US 5,674,534 A
  • Filed: 06/07/1995
  • Issued: 10/07/1997
  • Est. Priority Date: 06/11/1992
  • Status: Expired due to Fees
First Claim
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1. A composition for the sustained release of biologically active, non-aggregated erythropoietin from a polymeric matrix, comprising:

  • a) a biodegradable polymer; and

    b) particles of biologically active, aggregation-stabilized erythropoietin, wherein said particles include erythropoietin in contact with a salting-out salt, and wherein said erythropoietin particles are dispersed within the polymeric matrix.

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