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Method and apparatus for controlling concentrations in vivos and in tubing systems

  • US 5,676,645 A
  • Filed: 06/06/1995
  • Issued: 10/14/1997
  • Est. Priority Date: 03/04/1992
  • Status: Expired due to Term
First Claim
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1. A method for regulating the amount of anticoagulant infused to a donor, comprising the steps of:

  • removing the blood from the donor;

    treating the blood in the extracorporeal blood treatment apparatus;

    returning at least a fraction of the processed blood to the donor at a flow rate;

    infusing an amount of anticoagulant in blood to the donor at an anticoagulant infusion rate;

    predicting a maximum level of anticoagulant that may be present in the donor;

    estimating the level of anticoagulant in the donor;

    varying the amount of anticoagulant added to the blood at an anticoagulant infusion rate so that the estimated level of anticoagulant in the donor does not exceed the predicted maximum level of anticoagulant in the donor;

    and varying the flow rate of the processed blood returned to the donor to maximize the flow rate while simultaneously preventing the estimated level of anticoagulant in the donor from exceeding the predicted maximum level of anticoagulant in the donor.

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