Iontophoretic drug delivery apparatus and method for use
First Claim
1. An iontophoretic drug delivery device for personal use for sell;
- administering a medicament into a person'"'"'s skin, said device comprising a base assembly and a detachable applicator electrode wherein said base assembly comprises;
(a) a case having an elongate, substantially cylindrical outer surface having a size and shape adapted to be comfortably grasped within a person'"'"'s hand and wherein at least a portion of said outer surface is a tactile electrode formed of an electrically conductive material;
(b) a bipolar electrical power means having a first pole and a second pole;
said electrical power means being enclosed within said case and wherein said first pole is in electrical communication with said tactile electrode;
and wherein said applicator electrode comprises a porous matrix portion, a module containing a unit dose of medicament, an electrically conductive working electrode and attachment means adapted for releasably attaching said application electrode to said base assembly to provide electrical connection between said working electrode and said second pole of said electrical power means and wherein said iontophoretic delivery device is operable for releasing said medicament to permeate said porous matrix portion and delivering said medicament from said porous matrix portion to a portion of the person'"'"'s skin in contact with matrix portion of said applicator electrode.
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Accused Products
Abstract
A portable iontophoresis apparatus for facilitating delivery of medication across the cutaneous membrane into adjacent underlying tissues and blood vessels. The apparatus employs a modular, detachable non-reusable medicament-containing applicator electrode which is adapted to attach to a base assembly. The apparatus is designed to be hand-held and includes a circumferential tactile electrode band on the base assembly which provides electrical connection between the skin of the user'"'"'s hand and one pole of a bipolar power source housed within the base assembly. The opposing pole of the power source is connected to the applicator electrode. The user'"'"'s body completes the electrical circuit between the applicator and tactile electrodes. A method for using the device for the treatment of Herpes simplex infection and related viral infections which produce similar cutaneous lesions is presented. The apparatus, when used in accordance with the method described herein, demonstrated >90% treatment efficacy in clinical trials.
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Citations
5 Claims
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1. An iontophoretic drug delivery device for personal use for sell;
- administering a medicament into a person'"'"'s skin, said device comprising a base assembly and a detachable applicator electrode wherein said base assembly comprises;
(a) a case having an elongate, substantially cylindrical outer surface having a size and shape adapted to be comfortably grasped within a person'"'"'s hand and wherein at least a portion of said outer surface is a tactile electrode formed of an electrically conductive material; (b) a bipolar electrical power means having a first pole and a second pole;
said electrical power means being enclosed within said case and wherein said first pole is in electrical communication with said tactile electrode;and wherein said applicator electrode comprises a porous matrix portion, a module containing a unit dose of medicament, an electrically conductive working electrode and attachment means adapted for releasably attaching said application electrode to said base assembly to provide electrical connection between said working electrode and said second pole of said electrical power means and wherein said iontophoretic delivery device is operable for releasing said medicament to permeate said porous matrix portion and delivering said medicament from said porous matrix portion to a portion of the person'"'"'s skin in contact with matrix portion of said applicator electrode. - View Dependent Claims (2, 3, 4, 5)
- administering a medicament into a person'"'"'s skin, said device comprising a base assembly and a detachable applicator electrode wherein said base assembly comprises;
Specification