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Concentrated aqueous solutions of argatroban

  • US 5,679,690 A
  • Filed: 02/02/1995
  • Issued: 10/21/1997
  • Est. Priority Date: 02/03/1994
  • Status: Expired due to Term
First Claim
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1. A concentrated aqueous solution of argatroban, which comprises argatroban, one or more micelle-forming agents and one or more lipoid substances, wherein the micelle-forming agent is a cholic acid derivative of general formula:

  • ##STR2## in which each of R1, R2 and R3 independently represents a hydrogen atom, hydroxy group or keto exocyclic group, and R4 represents a carboxy group or a carboxy group bonded by an amide linkage to the amino group of an amino acid.

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