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Non-destructive identification of tablet and tablet dissolution by means of infared spectroscopy

  • US 5,679,954 A
  • Filed: 11/14/1994
  • Issued: 10/21/1997
  • Est. Priority Date: 11/14/1994
  • Status: Expired due to Fees
First Claim
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1. An automatic non-destructive near infrared system comprising a continuous supply of tablets loaded on a conveyor via an actuator mechanism maintaining a sequence of said tablets on said conveyor, a receptacle comprising an upper plate holding a bundle of at least one fiber optic cable receiving infrared waves from an opto-directional coupler, conveying near infrared light waves, said receptacle further comprising a pair of lower parts accommodating presence of objects, an air jet means for directing the objects to rest at said receptacle and to depart from said receptacle, said tablets departing from receptacle are arranged in storage maintaining said sequence, said bundle of at least one fiber optic cable carrying upstream and downstream layers of fiber optics, said upstream cable layers feeding infrared waves and said downstream cable layers conveying reflected infrared waves to an optical switch means, a means for conveying and amplifying data received from said downstream cable layers to an infrared spectrophotometer to a computer and further conveyed by electronic means to a computer display monitor displaying status of said tablets in Fourier Transformation form, said Fourier Transformation form is integrated and conveyed to a plotter comprising two directional motions responding to said computer output drafting the status of said spectrum, an output of integration of said Fourier Transformation form is further conveyed to an alarm means declaring a status of said tablets, said alarm means comprising sensorial information conveyed to a supply means of tablets, said output of integration of said Fourier Transformation form yields linear phenomena conveyed to said plotter and said computer display plots integrated absorbency in a first direction and nominal hardness (dissolution) of the tablets in a second direction perpendicular to said first direction.

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