Method and apparatus for detecting blood pressure by blood pressure sounds in the presence of significant noise
First Claim
1. A method for detecting a blood pressure sound in a patient, comprising the steps of:
- (a) placing a first microphone on the patient near the location of an artery, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone;
(b) placing a second microphone on the patient having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone;
(c) applying pressure to the artery such that the artery will be forced closed during part of a heart beat cycle and will be forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced;
(d) selecting portions of the first and second microphone signals having characteristics corresponding to blood pressure sounds;
(e) multiplying the selected portions of the first and second microphone signals at selected points in time to generate a microphone signal product; and
(f) indicating the detection of a blood pressure sound when the microphone signal product is negative for multiple consecutive selected points in time corresponding to a selected time period.
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Accused Products
Abstract
A method and apparatus is provided for detecting blood pressure sounds produced by the opening snap of an artery in a patient in the presence of significant noise using the phase information contained in two microphone signals. The two microphones are placed on a patient along the axis of an artery with their centers separated by a distance such that blood pressure sounds picked up by the microphones will be out of phase. Pressure is applied to the artery such that the artery opens and closes during each heart cycle, the opening snap of the artery producing blood pressure sounds. The two microphone signals are filtered, preferably using band pass filters having pass bands corresponding to the frequency of the blood pressure sounds. The filtered microphone signals are sampled and multiplied together or convolved in the frequency domain to generate a microphone signal product. If the microphone signal product is negative, the detection of a valid blood pressure signal for that sampling time is indicated. In an alternative embodiment, the slope of the two microphone signals at the sample time is also determined. A valid blood pressure signal is indicated when the microphone signal product is negative and either the two microphone signal slopes have inverse signs or are both less than a selected slope threshold. A selected number of consecutive valid blood pressure signal detections indicates the detection of a blood pressure sound. The detection of blood pressure sounds at a range of cuff pressures is used to determine the systolic and diastolic blood pressure levels of the patient.
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Citations
45 Claims
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1. A method for detecting a blood pressure sound in a patient, comprising the steps of:
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(a) placing a first microphone on the patient near the location of an artery, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (b) placing a second microphone on the patient having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (c) applying pressure to the artery such that the artery will be forced closed during part of a heart beat cycle and will be forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (d) selecting portions of the first and second microphone signals having characteristics corresponding to blood pressure sounds; (e) multiplying the selected portions of the first and second microphone signals at selected points in time to generate a microphone signal product; and (f) indicating the detection of a blood pressure sound when the microphone signal product is negative for multiple consecutive selected points in time corresponding to a selected time period. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method for detecting blood pressure by blood pressure sounds in a patient, comprising the steps of:
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(a) placing a first microphone on the patient near the location of an artery, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (b) placing a second microphone on the patient having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (c) applying pressure to the artery at a plurality of pressure levels ranging from above a systolic blood pressure level of the patient to below a diastolic blood pressure level of the patient, the artery being forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (d) selecting portions of the first and second microphone siqnals having characteristics corresponding to blood pressure sounds; (e) multiplying the selected portions of the first and second microphone siqnals at selected points in time to generate a microphone signal product; (f) indicating the detection of a blood pressure sound when the microphone signal product is negative for multiple consecutive selected points in time corresponding to a selected time period; (g) repeating the steps of selecting portions of the microphone signals, multiplying the microphone signals, and indicating the detection of a blood pressure sound at each of the plurality of pressure levels; and (h) displaying a systolic blood pressure level of the patient as a highest of the plurality of pressure levels at which a blood pressure sound is indicated as being detected and displaying a diastolic blood pressure level of the patient as a lowest of the plurality of pressure levels at which a blood pressure sound is indicated as being detected. - View Dependent Claims (17, 18)
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19. A method for detecting a blood pressure sound in a patient, comprising the steps of:
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(a) placing a first microphone on the patient near the location of an artery, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (b) placing a second microphone on the patient having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (c) applying pressure to the artery such that the artery will be forced closed during part of a heart beat cycle and will be forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (d) filtering the first and second microphone signals with band pass filters having pass bands corresponding approximately to the frequency range of the blood pressure sound; (e) multiplying the filtered first and second microphone signals at selected points in time to generate a microphone signal product; (f) indicating the detection of a valid blood pressure signal when the microphone signal product is negative; and (g) indicating the detection of a blood pressure sound when the detection of valid blood pressure signals are indicated for multiple consecutive selected points in time corresponding to a selected time period. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method for detecting blood pressure by blood pressure sounds in a patient, comprising the steps of:
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(a) placing a first microphone on the patient near the location of an artery, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (b) placing a second microphone on the patient having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (c) applying pressure to the artery at a plurality of pressure levels ranging from above a systolic blood pressure level of the patient to below a diastolic blood pressure level of the patient, the artery being forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (d) filtering the first and second microphone signals with band pass filters having pass bands corresponding approximately to the frequency range of the blood pressure sound; (e) multiplying the filtered first and second microphone signals at selected points in time to generate a microphone signal product; (f) indicating the detection of a valid blood pressure signal when the microphone signal product is negative; (g) indicating the detection of a blood pressure sound when the detection of valid blood pressure signals are indicated for multiple consecutive selected points in time corresponding to a selected time period; (h) repeating the steps of filtering the microphone signals, multiplying the microphone signals, indicating the detection of a valid blood pressure signal, and indicating the detection of a blood pressure sound at each of the plurality of pressure levels; and (i) displaying a systolic blood pressure level of the patient as a highest of the plurality of pressure levels at which a blood pressure sound is indicated as being detected and displaying a diastolic blood pressure level of the patient as a lowest of the plurality of pressure levels at which a blood pressure sound is indicated as being detected. - View Dependent Claims (32, 33)
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34. A method for detecting a valid blood pressure sound signal in a patient, comprising the steps of:
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(a) placing a first microphone on the patient near the location of an artery, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (b) placing a second microphone on the patient having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (c) applying pressure to the artery such that the artery will be forced closed during part of a heart beat cycle and will be forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (d) filtering the first and second microphone signals with a filter having a pass band corresponding approximately to the frequency range of the blood pressure sound; (e) multiplying the filtered first and second microphone signals at selected points in time to generate a microphone signal product; (f) determining slopes of the first and second filtered microphone signals at the selected points in time; and (g) indicating the detection of a blood pressure sound when the microphone signal product is negative and either the slopes of the first and second microphone signals have inverse signs or the slopes of the first and second microphone signals are both less than a selected slope threshold value for multiple selected points in time corresponding to a selected time period.
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35. An apparatus for detecting blood pressure sounds in a patient, comprising:
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(a) an inflatable cuff adapted to be wrapped around a limb of a patient; (b) a first microphone fixed in the inflatable cuff, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (c) a second microphone fixed in the inflatable cuff and having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (d) means for inflating the inflatable cuff to thereby apply pressure to the limb of a patient such that an artery in the patient'"'"'s limb will be forced closed during part of a heart beat cycle and will be forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (e) means for selecting portions of the first and second microphone signals having characteristics corresponding to blood pressure sounds; (f) means for multiplying the selected portions of the first and second microphone signals at selected points in time to generate a microphone signal product; (g) means for indicating the detection of a valid blood pressure signal when the microphone signal product is negative; and (h) means for indicating the detection of a blood pressure sound when the detection of valid blood pressure signals are indicated for multiple consecutive selected points in time corresponding to a selected time period. - View Dependent Claims (36, 37, 38, 39, 40, 41, 42, 43)
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44. An apparatus for detecting blood pressure by blood pressure sounds in a patient, comprising:
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(a) an inflatable cuff adapted to be wrapped around a limb of a patient; (b) a first microphone fixed in the inflatable cuff, the first microphone producing a first microphone signal in response to blood pressure sounds and noise picked up by the first microphone; (c) a second microphone fixed in the inflatable cuff and having a center separated a distance from a center of the first microphone such that a blood pressure sound picked up by the first microphone will be picked up out of phase by the second microphone, the second microphone producing a second microphone signal in response to blood pressure sounds and noise picked up by the second microphone; (d) means for inflating and deflating the inflatable cuff to apply pressure to the limb of the patient at a plurality of pressure levels ranging from above a systolic blood pressure level of the patient to below a diastolic blood pressure level of the patient, an artery in the patient'"'"'s limb being forced open during part of the heart beat cycle when the patient'"'"'s blood pressure exceeds the pressure applied to the artery, the opening of the artery causing a blood pressure sound to be produced; (e) means for selecting portions of the first and second microphone siqnals having characteristics corresponding to blood pressure sounds; (f) means for multiplying the selected portions of the first and second microphone siqnals at selected points in time to generate a microphone signal product; (g) means for indicating the detection of a valid blood pressure signal when the microphone signal product is negative; (h) means for indicating the detection of a blood pressure sound when the detection of valid blood pressure signals are indicated for multiple consecutive selected points in time corresponding to a selected time period; (i) means for measuring the cuff pressure at each of the plurality of pressure levels; (j) means for selecting portions of the microphone signals, multiplying the microphone signals, indicating the detection of a valid blood pressure signal, and indicating the detection of a blood pressure sound at each of the plurality of pressure levels; and (k) means for displaying a systolic blood pressure level of the patient as a highest of the measured cuff pressure levels at which a blood pressure sound is indicated as being detected and displaying a diastolic blood pressure level of the patient as a lowest of the measured cuff pressure levels at which a blood pressure sound is indicated as being detected. - View Dependent Claims (45)
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Specification