Filter coated with antimicrobial material

• US 5,681,468 A
• Filed: 02/12/1996
• Issued: 10/28/1997
• Est. Priority Date: 12/20/1993
• Status: Expired due to Fees

• Current Assignee: Surfacine Development Company LLC
• Original Assignee: Biopolymerix, Inc.
• Inventors: Yurkovetskiy, Alexander, Shalon, Tadmor, Sawan, Samuel P., Subramanyam, Sundar
• Primary Examiner(s): FORTUNA, ANA M
• Application Number:
  US08/599,810
• Time in Patent Office: 624 Days
• Field of Search: 210/651, 210/650, 210/490, 210/506, 210/473, 210/321.84, 210/321.75, 210/500.25, 210/500.27, 427/245, 264/45.1
• US Class Current: 210/500.25
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/24 containing ingredients to enhance the sticking of the active ingredients
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A61J 1/145 using air filters
• CPC Class Codes: A61J 1/1456 using liquid filters
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: A61L 2/16 using chemical substances
• CPC Class Codes: B01D 2239/0442 Antimicrobial, antibacterial, antifungal additives apparatus incorporating such gas filtering material B01D46/0028
• CPC Class Codes: B01D 2239/0478 on a layer of the filter
• CPC Class Codes: B01D 2323/02 Hydrophilization
• CPC Class Codes: B01D 2325/48 Antimicrobial properties
• CPC Class Codes: B01D 39/00 Filtering material for liquid or gaseous fluids
• CPC Class Codes: B01D 39/16 of organic material, e.g. synthetic fibres
• CPC Class Codes: B01D 39/2027 Metallic material
• CPC Class Codes: B01D 67/0069 by deposition from the liquid phase, e.g. electrochemical deposition B01D67/0046 takes precedence
• CPC Class Codes: B01D 67/0072 by deposition from the gaseous phase, e.g. sputtering, CVD, PVD
• CPC Class Codes: B01D 67/0088 Physical treatment with compounds, e.g. swelling, coating or impregnation
• CPC Class Codes: B01D 67/009 with wave-energy, particle-radiation or plasma
• CPC Class Codes: B01D 69/02 : characterised by their properties
• CPC Class Codes: B01D 69/12 : Composite membranes; Ultra-thin membranes
• CPC Class Codes: B01D 71/022 : Metals
• CPC Class Codes: B01D 71/02231 : Palladium
• CPC Class Codes: B01D 71/02232 : Nickel
• CPC Class Codes: B05B 11/047 : characterised by the outlet or venting means B05B11/041 and B05B11/042 take precedence
• CPC Class Codes: B65D 47/18 : for discharging drops; Droppers droppers in general B01L3/00; pipettes connected to container closures B01L3/0282
• CPC Class Codes: B65D 81/24 : Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with thermal insulation B65D81/38

Abstract

A liquid dispenser for dispensing sterile liquid comprising a container for storing the sterile liquid, a nozzle assembly mounted on the container, and a filter which has at least one surface and a plurality of its pores coated with a metallic material, e.g., a metal or metal oxide or metal salt, that is bacteriostatic or bacteriocidal, is described. The metal coated filter, methods for coating the filter, and methods for using the liquid dispenser are also provided.

Claims

1. A filter having an upstream surface and a downstream surface having pores providing liquid conduits interconnecting said upstream and said downstream surfaces for liquid passage from one of said surfaces to the other,

said pores having a pore size so as to preclude passage of microorganisms therethrough and so as to permit passage of liquid and air therethrough,

wherein the downstream surface of said filter is at least partially coated with an antimicrobial material comprising a combination of a polycationic polymeric material and a bacteriostatic or bactericidal metallic material comprising a metal salt, and

wherein said filter further is at least partially coated within a plurality of said pores with said antimicrobial material.

2. The filter of claim 1 wherein said metal salt is silver halide.

3. The filter of claim 2 wherein the silver halide is silver iodide.

4. The filter of claim 1 wherein said filter is at least partially coated on the upstream surface with said antimicrobial material.

5. The filter of claim 1 wherein the polycationic polymeric material is polyhexamethylene biguanide.