Biological fluid analyzing device
First Claim
1. A biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample, comprising:
- a body comprising an upper and a lower parallel plates;
a sample-receiving port and a pump-connection port, each defined in an outer surface of said body;
a single fluid pathway defined between facing surfaces of said upper and lower plates, said fluid pathway fluidly connecting said sample-receiving port and said pump-connection port;
at least one sample-treating chamber and at least one optical-measuring chamber, each chamber being defined between said facing surfaces of said upper and lower plates and each chamber defining a portion of said fluid pathway, wherein the pathway is a capillary.
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Accused Products
Abstract
The biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample has a sample receiving port 1 and a pump connection port 5. Between the sample receiving port 1 and the pump connection port 5, the analyzing device has either a combination of at least one sample-treating chamber 2a, 2b, 2c and at least one optical-measuring chamber 3a, 3b, or a combination of at least one sample-treating chamber, at least one optical-measuring chamber and at least one waste liquid reservoir 4. The sample receiving port 1 is connected with one sample-treating chamber; the pump connection port 5 is connected with a pathway 6 or waste liquid reservoir 4; and the sample-treating chamber and optical-measuring chamber are interconnected with the pathway, or the sample-treating chamber, optical-measuring chamber and waste liquid reservoir are interconnected with the pathway. This construction allows a series of reaction steps to be performed without being affected by physical properties of a liquid sample and thereby assures high level of precision in analyzing the liquid sample. This construction also enables measurements to be made easily.
259 Citations
25 Claims
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1. A biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample, comprising:
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a body comprising an upper and a lower parallel plates; a sample-receiving port and a pump-connection port, each defined in an outer surface of said body; a single fluid pathway defined between facing surfaces of said upper and lower plates, said fluid pathway fluidly connecting said sample-receiving port and said pump-connection port; at least one sample-treating chamber and at least one optical-measuring chamber, each chamber being defined between said facing surfaces of said upper and lower plates and each chamber defining a portion of said fluid pathway, wherein the pathway is a capillary. - View Dependent Claims (2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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4. A biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample, comprising:
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a body comprising an upper and a lower parallel plates; a sample-receiving port and a pump-connection port, each defined in an outer surface of said body; a single fluid pathway defined between facing surfaces of said upper and lower plates, said fluid pathway fluidly connecting said sample-receiving port and said pump-connection port; at least one sample-treating chamber and at least one optical-measuring chamber, each chamber being defined between said facing surfaces of said upper and lower plates and each chamber defining a portion of said fluid pathway; and at least one waste liquid reservoir chamber between the sample receiving port and the pump-connection port, and connected to said pathway.
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16. A biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample, comprising:
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a body comprising an upper and a lower parallel plates; a sample-receiving port and a pump-connection port, each defined in an outer surface of said body; a single fluid pathway defined between facing surfaces of said upper and lower plates, said fluid pathway fluidly connecting said sample-receiving port and said pump-connection port; at least one sample-treating chamber and at least one optical-measuring chamber, each chamber being defined between said facing surfaces of said upper and lower plates and each chamber defining a portion of said fluid pathway, wherein said body comprises an upper plate and a lower plate, said upper plate being provided with the sample-receiving port and the pump-connection port, and one of the upper plate and the lower plate being provided with at least one sample-treating chamber, at least one optical-measuring chamber and pathway, such that upon coupling said upper plate to said lower plate, said at least one sample-treating chamber, said at least one optical-measuring chamber and said pathway are formed; and further comprising at least one waste liquid reservoir chamber between the sample-receiving port and the pump-connection port and connected to the pathway, wherein the at least one sample-treating chamber, at least one optical-measuring chamber, pathway and at least one waste liquid reservoir are each provided in the lower plate.
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17. A biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample, comprising:
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a body comprising an upper and a lower parallel plates; a sample-receiving port and a pump-connection port, each defined in an outer surface of said body; a single fluid pathway defined between facing surfaces of said upper and lower plates, said fluid pathway fluidly connecting said sample-receiving port and said pump-connection port; at least one sample-treating chamber and at least one optical-measuring chamber, each chamber being defined between said facing surfaces of said upper and lower plates and each chamber defining a portion of said fluid pathway; wherein a gas-permeable film and an air layer isolated by the gas-permeable film are provided in the at least one sample-treating chamber.
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18. A biological fluid analyzing device for analyzing biological fluid by measuring optical characteristics of a sample, comprising:
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a body comprising an upper and a lower parallel plates; a sample-receiving port and a pump-connection port, each defined in an outer surface of said body; a single fluid pathway defined between facing surfaces of said upper and lower plates, said fluid pathway fluidly connecting said sample-receiving port and said pump-connection port; at least one sample-treating chamber and at least one optical-measuring chamber, each chamber being defined between said facing surfaces of said upper and lower plates and each chamber defining a portion of said fluid pathway; and a blood corpuscle-separating portion in the form of a filter through which blood corpuscles cannot pass disposed adjacent the sample-receiving port and securely held at its outer periphery by a retaining portion defined in the body. - View Dependent Claims (19, 20)
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21. A biological fluid analyzing device of laminar form comprising at least two adjacent generally parallel layers, a single fluid pathway being defined between the adjacent layers, the fluid pathway leading between and fluidly coupling a first port and a second port, the fluid pathway being in flow communication with at least first and second chambers along its length, at least said first chamber being provided with at least one light passage means, whereby a change in optical properties of material located in said first chamber can be measured from outside the device;
- wherein a wall of at least a portion of the pathway and the chambers is a gas permeable liquid impermeable membrane which is in contact with an air layer, whereby oxygen can pass through the membrane into the pathway or chamber.
- View Dependent Claims (22, 23, 24, 25)
Specification