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Canister containing aerosol formulations containing P134a and particulate medicaments

  • US 5,683,676 A
  • Filed: 05/19/1995
  • Issued: 11/04/1997
  • Est. Priority Date: 12/12/1991
  • Status: Expired due to Term
First Claim
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1. A canister suitable for delivering a pharmaceutical aerosol formulation for inhalation therapy which comprises a container capable of withstanding the vapor pressure of the propellant used, which container is closed with a metering valve and contains a pharmaceutical aerosol formulation consisting essentially of a particulate medicament which is salmeterol or a physiologically acceptable salt or solvate thereof and 1,1,1,2-tetrafluoroethane as propellant, which formulation contains less than 0.0001% w/w surfactant based upon the weight of medicament, the particulate medicament being present in an amount of 0.005 to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns.

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