Drug delivery system and method

• US 5,685,842 A
• Filed: 04/22/1996
• Issued: 11/11/1997
• Est. Priority Date: 04/22/1996
• Status: Expired due to Term

• Current Assignee: Hospira Incorporated (Pfizer Inc.)
• Original Assignee: Abbott Laboratories
• Inventors: Drivas, Nicoloas A.
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US08/635,983
• Time in Patent Office: 568 Days
• Field of Search: 604/49, 604/86, 604/88, 604/240, 604/241, 604/243, 604/201, 604/206, 604/283, 604/905
• US Class Current: 604/500
• CPC Class Codes: A61M 39/26 Valves closing automatically on disconnecting the line and opening on reconnection thereof check valves A61M39/24
• CPC Class Codes: Y10S 604/905 Aseptic connectors or couplings, e.g. frangible, piercable

Abstract

A fluid delivery set for delivering fluid from a primary container to a patient. The set includes a conduit defining a fluid flow path. A first connector constructed to be fluidly connected to a primary container is mounted on a first end portion of the conduit. A second connector is mounted on a second end portion of the conduit. The second connector includes a first end portion and a second end portion, the first end portion of the second connector being mounted on the second end portion of the conduit. The second connector defines a fluid flow path therethrough. A pierceable seal is disposed in and fluidly seals the fluid flow path defined through the second connector. The second connector further includes a piercing member having a piercing tip. The piercing tip is constructed to pierce the pierceable member when relative movement is effected between the pierceable member and the piercing member, whereupon fluid communication is established through the pierceable seal.

Claims

1. A fluid delivery set comprising:

a conduit defining a fluid flow path, said conduit having a first end portion and a second end portion;

a first connector mounted on said first end portion of said conduit, said first connector being fluidly connectable to a source of fluid, said first connector defining a fluid flow path therethrough, said fluid flow path defined by said first connector in fluid communication with said fluid flow path defined by said conduit; and

a second connector having a first end portion and a second end portion, said first end portion of said second connector mounted on said second end portion of said conduit, said second connector defining a fluid flow path therethrough, said fluid flow path defined by said second connector being in fluid communication with said fluid flow path defined by said conduit, a pierceable seal disposed in and fluidly sealing said fluid flow path defined by said second connector, said second connector further including a piercing member having a piercing tip, said piercing member defining a fluid flow path therethrough, said piercing member disposed in said fluid flow path defined by said second connector, said piercing tip being disposed on a first side of said pierceable seal when said pierceable seal is in a first position, said pierceable seal being movable from said first position to a second position by a male luer member inserted into said second end of said second connector, said pierceable seal being pierceable by said piercing tip as said pierceable seal is moved from said first position to said second position, said piercing tip being disposed on a second side of said pierceable seal when said pierceable seal is in said second position, said piercing member establishing fluid communication through said pierceable seal when said pierceable seal is in said second position.

2. A fluid delivery set in accordance with claim 1, wherein said set further comprises:

a transfer tube set, said transfer tube set comprising;

a conduit defining a fluid flow path, said conduit having a first end portion and a second end portion;

a male luer member mounted on said first end portion of said conduit, said male luer member constructed to move said pierceable seal from said first position to said second position, said male luer member defining a fluid flow path therethrough, said fluid flow path defined by said male luer member fluidly connecting said fluid flow path defined by said second connector and said fluid flow path defined by said conduit of said transfer tube set when said pierceable seal is in said second position; and

a connector mounted on said second end portion of said conduit.

3. A fluid delivery set in accordance with claim 2, wherein said transfer set further comprises a fluid flow control device disposed on said conduit intermediate said male luer member and said connector.

4. A fluid delivery set in accordance with claim 2, wherein said transfer set further comprises a one-way valve mounted in said fluid flow path defined by said conduit at a position intermediate said male luer member and said connector.

5. A fluid delivery set in accordance with claim 1, wherein said second connector further comprises a protruding member extending outwardly from said second chamber, said protruding member defining a fluid flow path therethrough, said fluid flow path defined through said second connector comprising said fluid flow path defined by said protruding member, said protruding member being connectable to said second end portion of said conduit.

6. A fluid delivery set comprising:

a conduit defining a fluid flow path, said conduit having a first end portion and a second end portion;

a first connector mounted on said first end portion of said conduit, said first connector being fluidly connectable to a source of fluid, said first connector defining a fluid flow path therethrough, said fluid flow path defined by said first connector being in fluid communication with said fluid flow path defined by said conduit; and

a second connector having a first end portion and a second end portion, said first end portion of said second connector mounted on said second end portion of said conduit, said second connector defining a fluid flow path therethrough, said fluid flow path defined by said second connector being in fluid communication with said fluid flow path defined by said conduit, a pierceable seal disposed in and fluidly sealing said fluid flow path defined by said second connector, said second connector further including a piercing member having a piercing tip mounted on a proximal end portion of said piercing member, said piercing member movably disposed in said fluid flow path defined by said second connector, said piercing member defining a fluid flow path therethrough, said piercing member being movable between a first position and a second position, said piercing member having a distal end portion constructed to be engageable in substantial end-to-end abutment by a male luer member inserted into said second connector at said second end portion of said second connector, said piercing member being movable between said first and second positions by a male luer member inserted into said second connector at said second end portion of said second connector, said piercing tip being disposed on a first side of said pierceable seal when said piercing tip is in said first position, said pierceable seal being pierceable by said piercing tip as said piercing member is moved by a male luer member from said first position to said second position, said piercing tip being disposed on a second side of said pierceable seal when said piercing member is in said second position, said piercing member establishing fluid communication through said pierceable seal when said pierceable seal is in said second position.

7. A fluid delivery set in accordance with claim 6, wherein said set further comprises:

a transfer tube set, said transfer tube set comprising;

a conduit defining a fluid flow path, said conduit having a first end portion and a second end portion;

a male luer member mounted on said first end portion of said conduit, said male luer member constructed to move said piercing member from said first position to said second position, said male luer member defining a fluid flow path therethrough, said fluid flow path defined by said male luer member fluidly connecting said fluid flow path defined by said second connector and said fluid flow path defined by said conduit of said transfer tube set when said piercing member is in said second position; and

a connector mounted on said second end portion of said conduit.

8. A fluid delivery set in accordance with claim 7, wherein said transfer set further comprises a fluid flow control device disposed on said conduit intermediate said male luer member and said connector.

9. A fluid delivery set in accordance with claim 7, wherein said transfer set further comprises a one-way valve mounted in said fluid flow path defined by said conduit at a position intermediate said male luer member and said connector.

10. A method for delivering fluid from a primary container to a patient, said method comprising the steps of:

providing an access tube set, said access tube set comprising;

a conduit defining a fluid flow path, said conduit having a first end portion and a second end portion;

a first connector mounted on said first end portion of said conduit, said first connector being fluidly connectable to a source of fluid, said first connector defining a fluid flow path therethrough, said fluid flow path defined by said first connector in fluid communication with said fluid flow path defined by said conduit; and

a second connector having a first end portion and a second end portion, said first end portion of said second connector mounted on said second end portion of said conduit, said second connector defining a fluid flow path therethrough, said fluid flow path defined by said second connector being in fluid communication with said fluid flow path defined by said conduit, a pierceable seal disposed in and fluidly sealing said fluid flow path defined by said second connector, said second connector further including a piercing member having a piercing tip, said piercing member disposed in said fluid flow path defined by said second connector, said piercing member defining a fluid flow path therethrough, said piercing tip being disposed on a first side of said pierceable seal when said pierceable seal is in a first position, said pierceable seal being movable from said first position to a second position by a male luer member inserted into said second end of said second connector, said pierceable seal being pierceable by said piercing tip as said pierceable seal is moved from said first position to said second position, said piercing tip being disposed on a second side of said pierceable seal when said pierceable seal is in said second position, said piercing member providing fluid communication through said pierceable seal when said pierceable seal is in said second position;

inserting a male luer member into said second end portion of said second connector;

drawing a volume of fluid into said male luer member from said access tube set;

disconnecting said male luer member from said second connector; and

delivering said volume of fluid from said male luer member to a patient.

11. A method for delivering fluid from a primary container to a patient, said method comprising the steps of:

a conduit defining a fluid flow path, said conduit having a first end portion and a second end portion;

a first connector mounted on said first end portion of said conduit, said first connector being fluidly connectable to a source of fluid, said first connector defining a fluid flow path therethrough, said fluid flow path defined by said first connector being in fluid communication with said fluid flow path defined by said conduit; and

a second connector having a first end portion and a second end portion, said first end portion of said second connector mounted on said second end portion of said conduit, said second connector defining a fluid flow path therethrough, said fluid flow path defined by said second connector being in fluid communication with said fluid flow path defined by said conduit, a pierceable seal disposed in and fluidly sealing said fluid flow path defined by said second connector, said second connector further including a piercing member having a piercing tip mounted on a proximal end portion of said piercing member, said piercing member defining a fluid flow path therethrough, said piercing member movably disposed in said fluid flow path defined by said second connector, said piercing member being movable between a first position and a second position, said piercing member having a distal end portion constructed to be engageable in substantial end-to-end abutment by a male luer member inserted into said second connector at said second end portion of said second connector, said piercing member being movable between said first and second positions by a male luer member inserted into said second connector at said second end portion of said second connector, said piercing tip being disposed on a first side of said pierceable seal when said piercing tip is in said first position, said pierceable seal being pierceable by said piercing tip as said piercing member is moved by a male luer member from said first position to said second position, said piercing tip being disposed on a second side of said pierceable seal when said piercing member is in said second position, said piercing member establishing fluid communication through said pierceable seal

when said pierceable seal is in said second position;

inserting a male luer member into said second end portion of said second connector;

drawing a volume of fluid into said male luer member from said access tube set;

disconnecting said male luer member from said second connector; and

delivering said volume of fluid from said male luer member to a patient.