Polymeric compositions for medical packaging and devices

• US 5,686,527 A
• Filed: 06/05/1995
• Issued: 11/11/1997
• Est. Priority Date: 11/16/1993
• Status: Expired due to Term

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Anderson, William, Nebgen, Gregg, Buan, Angeles Lillian, Ling, Michael T. K., Rosenbaum, Larry A., Laurin, Dean, Woo, Lecon, Ding, Yuan Pang Samuel, Hayward, Denise S., Hoppesch, Joseph P., Westphal, Stanley
• Primary Examiner(s): Woodward, Ana
• Application Number:
  US08/461,050
• Time in Patent Office: 890 Days
• Field of Search: 525/66, 525/74, 525/93
• US Class Current: 525/66
• CPC Class Codes: C08L 101/00 Compositions of unspecified macromolecular compounds
• CPC Class Codes: C08L 2203/02 for biomedical use
• CPC Class Codes: C08L 2205/08 containing additives to improve the compatibility between two polymers
• CPC Class Codes: C08L 23/02 not modified by chemical after-treatment
• CPC Class Codes: C08L 23/0815 Copolymers of ethene with aliphatic 1-olefins
• CPC Class Codes: C08L 23/0846 Copolymers of ethene with unsaturated hydrocarbons containing other atoms than carbon or hydrogen atoms
• CPC Class Codes: C08L 23/0853 Vinylacetate
• CPC Class Codes: C08L 23/0869 Acids or derivatives thereof
• CPC Class Codes: C08L 23/10 Homopolymers or copolymers of propene
• CPC Class Codes: C08L 2666/02 Organic macromolecular compounds, natural resins, waxes or and bituminous materials
• CPC Class Codes: C08L 2666/04 Macromolecular compounds according to groups C08L7/00 - C08L49/00, or C08L55/00 - C08L57/00; Derivatives thereof
• CPC Class Codes: C08L 2666/14 Macromolecular compounds according to C08L59/00 - C08L87/00; Derivatives thereof
• CPC Class Codes: C08L 2666/20 Macromolecular compounds having nitrogen in the main chain according to C08L75/00 - C08L79/00; Derivatives thereof
• CPC Class Codes: C08L 2666/24 Graft or block copolymers according to groups C08L51/00, C08L53/00 or C08L55/02; Derivatives thereof
• CPC Class Codes: C08L 51/06 grafted on to homopolymers or copolymers of aliphatic hydrocarbons containing only one carbon-to-carbon double bond
• CPC Class Codes: C08L 53/00 Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
• CPC Class Codes: C08L 53/02 of vinyl-aromatic monomers and conjugated dienes
• CPC Class Codes: C08L 77/00 Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain of polyhydrazides C08L79/06; of polyamideimides or polyamide acids C08L79/08; Compositions of derivatives of such polymers

Abstract

Multiple component polymer compositions for fabrication into articles. In particular, polymeric compositions comprising a heat resistant polymer; a radio frequency ("RF") susceptible polymer; a compatibilizing polymer; the composition having physical properties within the range a<40,000 psi; b>=70%; c<30%; d>1.0; e<0.1%; f<0.1%; g>=0.05; h<=60%; i=0; wherein: a is the mechanical modulus of the composition measured according to ASTM D-882; b is the percent recovery in length of the composition after an initial 20% deformation; c is the optical haze of the composition being 9 mils in thickness according to ASTM D-1003; d is the loss tangent of the composition at 1 Hz measured at melt processing temperatures; e is the elemental halogen content by weight of the composition; f is the low molecular weight water soluble fraction of the composition; g is the dielectric loss between 1 and 60 MHz and over temperatures of 25° to 250° C. of the composition; h sample creep measured at 121° C. for a 1 inch strip of the composition under 27 psi loading; and, i indicates the composition exhibits no strain whitening after being strained at moderate speeds of about 20 inches (50 cm) per minute to about 100% elongation (twice the original length) and the presence of strain whitening (indicated by 1) or lack thereof (indicated by 0) is noted.

Claims

1. A polymer based composition for fabricating into articles comprising:

a first polyolefin containing propylene units, the first polyolefin being in an amount of 30-60% by weight of the composition;

a second polyolefin containing no propylene units selected from the group consisting of polyethylene, ultra-low density polyethylene, polybutene-1, and butene-1 copolymers, the second polyolefin being in an amount within the range of from 35% to about 50% by weight of the composition;

a radio frequency susceptible polymer having a dielectric loss greater than 0.05 at 1-60 MHz and ambient temperature to 250°

C., the radio frequency polymer being selected from the group consisting of ethylene copolymers having 50-85% ethylene content with comonomers selected from the group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl alcohol, and vinyl acetate;

a styrenic block copolymer with hydrocarbon soft segments; and

,

the composition having physical properties within the range

a<

40,000 psi;

b>

=70%;

c<

30%;

d>

1.0;

e<

0.1%;

f<

0.1%;

g>

=0.05

h<

=60%;

wherein;

a is the mechanical modulus of the composition measured according to ASTM D-882;

b is the percent recovery in length of the composition after an initial 20% deformation;

c is the optical haze of the composition processed into a film 9 mils in thickness measured in accordance to ASTM D-1003;

d is the loss tangent of the composition at 1 Hz measured at melt processing temperatures;

e is the elemental halogen content by weight of the composition;

f is the weight fraction of components capable of leaching from the composition into an aqueous phase;

g is the dielectric loss between 1 and 60 MHz and over temperatures of 25°

to 250°

C. of the composition;

h is the sample creep measured at 121°

C. for a 1 inch strip of the composition under 27 psi loading; and

,

wherein the composition exhibits no strain whitening after being strained at moderate speeds of about 20 inches (50 cm) per minute to about 100% elongation (twice the original length).

2. The composition of claim 1 wherein the second polyolefin is an ultra low density polyethylene.

3. The composition of claim 1 wherein the second polyolefin is a polybutene-1.

4. The composition of claim 1 wherein the styrenic block copolymer with hydrocarbon soft segments is a styrene-ethylene-butene-styrene block copolymer.

5. The composition of claim 4 wherein the compatibilizing polymer is an SEBS block copolymer that is maleic anhydride functionalized.

6. The composition of claim 1 wherein the second polyolefin is in an amount in the range of 35-45% by weight of the composition.

7. The composition of claim 6 wherein the radio frequency susceptible polymer is in an amount within the range of 3-40% by weight of the composition.

8. The composition of claim 7 wherein the styrenic block copolymer is within the range of 5-40% by weight of the composition.

9. A polymer based composition for fabricating into articles comprising:

a polypropylene in an amount within the range of 30-60% by weight of the composition;

a second polyolefin containing no propylene units selected from the group consisting of polyethylene, ultra-low density polyethylene polybutene-1 and butene-1 copolymers in an amount within the range of 35-50% by weight of the composition;

an ethylene methyl acrylate copolymer in an amount within the range of 3-40% by weight of the composition; and

,

a styrene-ethylene-butene-styrene block copolymer in an amount within the range of 5-40% by weight of the composition.

10. The composition of claim 9 wherein the styrene-ethylene-butene-styrene block copolymer is maleic anhydride functionalized.

11. A polymer based composition for fabricating into articles comprising:

a first polyolefin containing propylene units, the first polyolefin being in an amount of 30-60% by weight of the composition;

a second polyolefin containing propylene units selected from the group consisting of polyethylene, ultra-low density polyethyelene, polybutene-1, and butene-1 copolymers, the second polyolefin being in an amount within the range of from 35% to about 50% by weight of the composition;

a radio frequency susceptible polymer having a dielectric loss greater than 0.05 at 1-60 MHz and ambient temperature to 250°

C., the radio frequency polymer being selected from the group consisting of ethylene copolymers having 50-85% ethylene content with comonomers selected from the group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl alcohol, and vinyl acetate;

a styrenic block copolymer with hydrocarbon soft segments; and

wherein the composition has a modulus of less than 40,000 psi measured according to ASTM D-882.

12. The composition of claim 11 wherein the radio frequency susceptible polymer is an ethylene methyl acrylate copolymer.

13. The composition of claim 12 wherein the radio frequency susceptible polymer is in an amount from 35-45% by weight of the composition.

14. The composition of claim 11 wherein the second polyolefin is an ultra-low density polyethylene.

15. The composition of claim 11 wherein the styrenic block copolymer is maleic anhydride functionalized.