Centrifuge with pivot-out, easy-load processing chamber

• US 5,690,602 A
• Filed: 08/30/1996
• Issued: 11/25/1997
• Est. Priority Date: 12/22/1993
• Status: Expired due to Fees

• Current Assignee: Yeda Research and Development Co. Ltd. (Weizmann Institute of Science)
• Original Assignee: Baxter International Inc.
• Inventors: Williamson, Warren P., Di Perna, Paul M., Brown, Richard I.
• Primary Examiner(s): Scherbel, David
• Assistant Examiner(s): TILL, TERRENCE R
• Application Number:
  US08/705,699
• Time in Patent Office: 452 Days
• Field of Search: 494/16-18, 494/20, 494/21, 494/45, 494/43
• US Class Current: 494/43
• CPC Class Codes: B04B 2005/045 having annular separation channels
• CPC Class Codes: B04B 5/0442 with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
• CPC Class Codes: F02B 2075/025 two

Abstract

A centrifuge comprising a yoke element that rotates about a rotational axis and a processing chamber having an axis. The processing chamber includes a bowl element, a spool element, and a mechanism for joining the spool and bowl elements for relative movement between a mutually cooperating position for centrifugal processing and a mutually separated position for loading. A hinge attaches the processing chamber to the yoke element for pivotal movement between an operating position and an access position. In the operating position, the spool and bowl elements are in their mutually cooperating position and oriented for rotation with the yoke element about the rotational axis. In the access position, the processing chamber axis lies outside the axis of rotation and the spool and bowl elements are oriented for movement from their mutually cooperating position into their mutually separated position.

Claims

1. A centrifuge comprising

a rotating element,

a drive mechanism coupled to the rotating element to rotate the rotating element about a rotational axis,

a processing element having an axis, and

a hinge coupling the processing element to the rotating element for rotation with the rotating element about the rotational axis, the hinge also permitting pivotal movement of the processing element between an operating position, in which the axis of the processing element lies in coaxial orientation with the rotational axis, and an access position, in which the processing element is cantilevered from the hinge and the axis of the processing element lies outside coaxial orientation with the rotational axis.

2. A centrifuge according to claim 1

and further including a processing chamber that is removably attached to the processing element when the processing element is in the access position and that is rotated with the processing element when the processing element is in the operating position.

3. A centrifuge according to claim 2

wherein the processing chamber includes tubing attachable to a fluid source, and

further including a tubing holder to releasably hold the tubing when the processing chamber is rotated with the processing element.

4. A centrifuge according to claim 1

and further including a base including at least one weight bearing member for engaging a support surface lying in a horizontal plane, the base including a mount supporting the rotating element with the rotational axis oriented in a plane that extends in a generally non-perpendicular relationship with the horizontal plane.

5. A centrifuge according to claim 4

wherein, when the processing element is in the access position, the axis of the processing chamber is oriented in a generally perpendicular relationship to the horizontal plane.

6. A centrifuge according to claim 1

wherein the processing element includes a bowl element having an interior area, a spool element having an exterior surface, and a mechanism joining the spool and bowl elements for movement between a mutually cooperating position, in which the spool element is enclosed within the interior area of the bowl element to define a processing space between the bowl wall and the exterior spool surface, and a mutually separated position, in which the spool element is at least partially out of the interior area of the bowl element to expose the exterior spool surface for access.

7. A centrifuge according to claim 6

wherein the spool element includes a mount exposed when the spool and bowl elements are in their mutually separated position for receiving a processing chamber upon the spool exterior surface and for retaining the processing chamber within the processing space when the spool and bowl elements are moved to their mutually cooperating position.