Hand-held inhalation-actuated spray device

• US 5,692,492 A
• Filed: 09/27/1995
• Issued: 12/02/1997
• Est. Priority Date: 02/16/1993
• Status: Expired due to Term

• Current Assignee: Aptar France S.A.S (AptarGroup Incorporated)
• Original Assignee: Valois (Mestdagh Family)
• Inventors: Buffet, Jacques, Bruna, Pascal
• Primary Examiner(s): Millin, V.
• Assistant Examiner(s): SRIVASTAVA, VIRENDRA KUMAR
• Application Number:
  US08/505,268
• Time in Patent Office: 797 Days
• Field of Search: 128/200.14, 128/205.23, 128/200.23, 128/200.24, 128/203.24, 128/203.12, 128/200.17, 128/203.15
• US Class Current: 128/200.23
• CPC Class Codes: A61M 15/008 Electronic counters
• CPC Class Codes: A61M 15/0081 Locking means
• CPC Class Codes: A61M 15/0083 Timers
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2205/215 Tilt detection, e.g. for warning or shut-off
• CPC Class Codes: B65D 83/201 Lever-operated actuators B65D83/206 takes precedence
• CPC Class Codes: B65D 83/386 actuation occurring by moving the aerosol container relative to the outer shell or external container

Abstract

A hand-held inhalation-actuated spray device including a housing; tank of substance to be sprayed; a dispenser mechanism for dispensing the substance; an inhale duct; a dispenser mechanism urging device for actuating the dispenser mechanism; a locking mechanism fixed on a plate inside the housing, which includes at least one locking latch member for locking or unlocking the action of the urging device; an unlocking mechanism for displacing the latch member towards its released position while suction exists in the inhale duct; the unlocking mechanism including an electrical actuator for actuating the latch member, an electronic control circuit for the electrical actuator, a suction sensor to deliver a suction signal to the electronic control circuit on detecting suction in the inhale duct, the electronic control circuit then causing the electrical actuator to move the latch member into its released position; the device being characterized in that it further includes a position sensor for detecting that the device is in a predetermined proper orientation, in which the position sensor is connected to the electronic control circuit and the electronic control circuit is adapted to trigger actuation of the device only if the position sensor detects the predetermined proper orientation of the device.

Claims

1. A hand-held spray device actuated by inhaling, the device comprising:

a housing;

a tank of substance to be sprayed, said tank having an end wall with a cylinder engaged thereover;

a dispenser device having an actuator member that is movable between a rest position and an actuated position, said dispenser device issuing a measured amount of said substance when the actuator member is displaced from its rest position to its actuated position, said actuator member being urged resiliently towards its rest position, the dispenser device also having an outlet for issuing said substance;

an inhale duct through which a patient can suck in air, and which communicates with said outlet for said substance;

actuator member urging means for urging said actuator member towards its actuated position;

a locking mechanism fixed on a plate inside said housing, for holding said tank and said cylinder in place when no suction has been detected in said inhale duct, said locking mechanism including at least one latch member movable between a latching position in which said latch member locks said actuator member urging means, and a released position in which said latch member no longer locks said urging means; and

unlocking means for displacing said latch member towards its released position while suction is being applied to said inhale duct;

said unlocking means comprising;

an electrical actuator for displacing said latch member;

an electronic control circuit connected to said electrical actuator for the purpose of controlling it;

a source of energy for powering said electronic control circuit; and

a suction sensor for applying a suction signal to said electronic control circuit on detecting suction in the inhale duct, the electronic control circuit then causing the electrical actuator to displace the latch member into its released position;

the device being characterized in that it further includes a position sensor for detecting any predetermined orientation of said device, in which said position sensor is connected to said electronic control circuit, and said electronic control circuit is adapted to trigger actuation of the device in said any predetermined orientation which is sensed by said position sensor.

2. A device according to claim 1, in which said suction sensor measures suction in said inhale duct relative to atmospheric pressure, and delivers a signal representative of the suction to the electronic control circuit.

3. A device according to claim 1, in which said position sensor includes means for detecting any predetermined orientation of the device and for causing said electronic control circuit to operate in a calibration mode, in which case the device is not actuated when the patient sucks from the inhale duct, but instead said electronic control circuit then determines the maximum amount of suction (Δ

P_m) set up in the inhale duct during suction, and it calculates and stores a trigger level of suction (Δ

P₀) as a function of said maximum suction (Δ

P_m), the device subsequently being actuated only when suction greater than or equal to said trigger level of suction (Δ

P₀) is detected in the inhale duct, and providing said electronic control circuit is not operating in its calibration mode.

4. A device according to claim 2, further including display means connected to the electronic control circuit to display a value for the air flow inhaled by the patient as a function of the suction measured in the inhale duct.

5. A device according to claim 1, including a shaking sensor for detecting shaking of said tank, in which said shaking sensor is connected to said electronic control circuit and said electronic control circuit is adapted to inhibit actuation of the device in the event of said tank not having been shaken during a second predetermined duration (T₂) preceding inhalation by the patient.

6. A device according to claim 1, in which the electronic control circuit is connected to warning means and said electronic control circuit is adapted to switch on the warning means to warn the patient that the device is not in any predetermined orientation for use, in the event that the position detector is not detecting the said any predetermined orientation.

7. A device according to claim 1, in which the substance to be sprayed is a liquid or a semi-liquid, the dispenser device is an aerosol valve or a pump, the electronic control circuit is connected to means for detecting displacement of the actuator member from its actuated position to its rest position, the electronic control circuit is connected to warning means, and said electronic control circuit is adapted to switch on the warning means, in the event that said displacement of the actuator member is detected while the device is not in its any predetermined orientation, to warn the patient that a next dose of said substance that the device dispenses will be incomplete.

8. A device according to claim 7, including means for actuating the valve or the pump manually, and in which said warning means tell the patient to actuate the valve or the pump manually for one occasion.

9. A device according to claim 7, including means for counting the number of doses of substance that are issued, and in which the issuing of said next dose is not counted.

10. A device according to claim 1, in which said position sensor includes a hollow column that extends vertically when the device is in its any predetermined orientation, said hollow column having a bottom end provided with two electrical contacts and said hollow column containing a drop of mercury which wets the two electrical contacts when the device is in its any predetermined orientation.

11. A device according to claim 10, in which said position sensor also serves as a shaking sensor, and said electronic control circuit is adapted to inhibit actuation of the device if said tank has not been shaken during a predetermined length of time (T₂) preceding inhalation by the patient.

12. A device according to claim 1, in which said electrical actuator includes an electromagnet, the latch member being in mechanical connection with an armature that is sensitive to magnetic fields, said armature being disposed facing said electromagnet, said electromagnet including a permanently magnetized core for maintaining said armature in a waiting position, said electromagnet further including a coil, and said electronic control circuit being adapted to power said coil with a current whose direction and magnitude are adapted to cause said armature to move into an actuated position, said armature thus driving the latch member from its latching position into its released position.

13. A device according to claim 12, in which the armature includes at least one stud co-operating with said latch member, said armature being mounted to rotate on a first axis and said latch member being mounted to rotate on a second axis, said first and second axes being secured to said plate, the stud driving the latch member in rotation from its latching position where it co-operates with a pin secured to the tank of substance to its released position.

14. A device according to claim 13, in which the electromagnet is a four-pole magnet and the armature is held in unstable equilibrium by opposing forces between identical poles while it is in its latching position, a signal from the electronic control circuit reducing an attraction force of the electromagnet in such a manner that the magnetic repulsion created by opposition between poles causes said armature to rotate towards its actuated position.

15. A device according to claim 12, in which a second latching member is provided that is rotatably mounted on a third axis secured to the plate, which member is substantially identical to the latch member and is disposed symmetrically relative to said latch member about a fourth axis supporting the armature, said second latch member cooperating with a second pin secured to the tank of substance and being driven into its released position by a second stud disposed symmetrically to the first stud on the armature, said second latch member preventing the dispenser device from returning to its rest position.

16. A device according to claim 12, in which the armature includes an arm extending outside the housing to enable said armature to be actuated manually, thereby enabling the latch member to be moved into its released position independently of any suction in the inhale duct.

17. A device according to claim 1, in which the dispenser device is secured to the tank of substance to be sprayed, the actuated position of the actuator member being such that said actuator member is moved towards said tank on passing from its rest position to its actuated position, the hand-held spray device including the housing secured to the inhale duct and to the actuator member, the handheld spray device further including a cover hinged on said housing and movable between a closed position in which it closes the inhale duct, and an open position in which it opens the inhale duct, the handheld spray device further including a compression spring adapted to urge the tank towards the actuator member to displace said actuator member into its actuated position, said compression spring having a first end which acts on the tank and a second end which acts on a thrust member, the cover including a lever-forming portion which bears against the thrust member when the cover is displaced into its open position, compressing the compression spring and said latch member locks the tank when it is in its latching position, the first end of the compression spring acts on an intermediate member fixed to said tank and said intermediate member includes a pin for receiving said latch member when it is in its latching position, said intermediate member then co-operating with the latch member to lock the tank.

18. A device according to claim 17, in which the actuator member is displaceable relative to the dispenser member parallel to an axis, the cover is mounted to rotate about two pivots, and the pivots are mounted in respective elongate guide paths parallel to the axis, the pivots thus being axially displaceable along their guide paths against the force of the compression spring, and the cover further including two lateral projections that are outwardly directed, and that co-operate with respective inwardly-directed projecting surfaces of the housing to constrain the pivots to move along their guide paths while compressing the compression spring when the cover passes from its closed position to its open position.

19. A device according to claim 18, in which the two guide paths include two axial ends and each has an opening disposed at the same level on both guide paths in a position that is intermediate between the two axial ends of each of the guide paths, to enable the pivots to escape from the guide paths when pressure is applied to the cover parallel to the axis, and simultaneously the cover is urged parallel to the axis towards said openings, the cover thus being removable from the housing, the housing including a loading opening of a size that enables the tank of substance together with its dispenser device to pass therethrough once the cover has been removed from the housing, the actuator member for the dispenser device being secured in removable manner to said housing, and the housing includes means for displacing the latch member into its released position independently of suction in the inhale duct.

20. A device according to claim 17, in which said lever-forming portion of the cover has a thrust surface in contact with the thrust member and said thrust surface includes two flats bearing against the thrust member respectively in the closed position and in the open position of the cover.

21. A device according to claim 17, in which the housing includes an opening of appropriate size to allow the tank together with its dispenser device to pass therethrough in order to be inserted into the housing or to be removed from the housing, and said housing further includes a support member which is secured to the actuator member and which is removably mounted in said opening.

22. A device according to claim 1, further including a sensor for detecting the presence of the tank and/or the dispenser device, said sensor being connected to the electronic control circuit to prevent operation of the device in the event of said tank being absent.

23. A device according to claim 1, further including a sensor for detecting the presence of the tank and/or of the dispenser device, said sensor being connected to the electronic control circuit, said electronic control circuit being adapted to count the number of tanks that have been installed in said device as a function of information from said sensor for detecting the presence thereof.

24. A device according to claim 23, in which said electronic control circuit is adapted to prevent the device being actuated if the number of tanks that have been installed in the device exceeds a predetermined number.