Device for determining myocardial function and corresponding procedure
First Claim
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1. A method of determining myocardial function of a patient'"'"'s heart, comprising:
- implanting an acceleration sensor in the right ventricle of the patient'"'"'s heart;
sensing a natural heart acceleration of the patient;
generating a signal representative of the natural heart acceleration; and
selecting at least one time segment of the natural heart acceleration signal based on a predetermined portion of a cardiac cycle; and
processing the selected time segment of the signal to provide an indication of myocardial function of the patient'"'"'s heart.
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Abstract
The device senses Natural Heart Acceleration (NHA), isolating at least one segment (t) thereof corresponding to an isovolumetric phase, such as isovolumetric contraction (P1, P2) and/or isovolumetric relaxation (P3, P4). Preferentially, the action of isolation of the aforesaid segment is made starting from the electrocardiogram (ECG) signal. Among other things, the device may be used to carry out pacing functions (pacemaker, defibrillator, pacer cardioverter defibrillator) and/or to pick up, possibly by telemetry, data on the myocardial function and/or also to control a system of drug administration.
152 Citations
68 Claims
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1. A method of determining myocardial function of a patient'"'"'s heart, comprising:
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implanting an acceleration sensor in the right ventricle of the patient'"'"'s heart; sensing a natural heart acceleration of the patient; generating a signal representative of the natural heart acceleration; and selecting at least one time segment of the natural heart acceleration signal based on a predetermined portion of a cardiac cycle; and processing the selected time segment of the signal to provide an indication of myocardial function of the patient'"'"'s heart. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. An apparatus for determining the myocardial function of a patient'"'"'s heart, comprising:
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a natural heart acceleration sensor sized for implantation within the right ventricle of the patient'"'"'s heart; an ECG sensor; and a processor operably connected to the natural heart acceleration sensor and the ECG sensor; wherein, the natural heart acceleration sensor measures the natural heart acceleration of the patient'"'"'s heart, the ECG sensor measures the ECG of the patient'"'"'s heart, the processor generates a first signal based on the measured natural heart acceleration, generates a second signal based on the measured ECG, and selects at least one time segment of the natural heart acceleration signal based on a predetermined portion of the ECG signal. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method of providing therapy to a patient'"'"'s heart comprising:
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implanting an acceleration sensor in the right ventricle of the patient'"'"'s heart; sensing a natural heart acceleration of the patient; generating a signal representative of the natural heart acceleration; selecting at least one time segment of the natural heart acceleration signal; and delivering therapy to the heart of the patient based on the selected time segment of the natural heart acceleration signal, wherein the at least one time segment is selected in an isovolumetric phase of the patient'"'"'s heart. - View Dependent Claims (23, 24, 25)
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26. A method of providing therapy to a patient'"'"'s heart comprising:
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implanting an acceleration sensor in the right ventricle of the patient'"'"'s heart; sensing a natural heart acceleration of the patient; generating a signal representative of the natural heart acceleration; selecting at least one time segment of the natural heart acceleration signal;
delivering therapy to the heart of the patient based on the selected time segment of the natural heart acceleration signal;sensing a cardiac cycle of the patient'"'"'s heart; generating a signal representative of the cardiac cycle; and
wherein the selection of the at least one time segment of the natural heart acceleration signal is based on a predetermined portion of the cardiac cycle. - View Dependent Claims (27, 28, 29, 30)
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31. A method of providing therapy to a patient'"'"'s heart comprising:
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implanting an acceleration sensor in the right ventricle of the patient'"'"'s heart; sensing a natural heart acceleration of the patient; generating a signal representative of the natural heart acceleration; selecting at least one time segment of the natural heart acceleration signal;
delivering therapy to the heart of the patient based on the selected time segment of the natural heart acceleration signal;measuring the heart beat rate; and varying the length of the selected time segment of the natural heart acceleration signal based on the heart beat rate. - View Dependent Claims (32, 33)
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34. An apparatus for providing therapy to a patient'"'"'s heart comprising:
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a natural heart acceleration sensor sized for implantation within the right ventricle of the patient'"'"'s heart; a signal generator coupled to the acceleration sensor and operative to generate a signal representative of the natural heart acceleration; a processor coupled to receive the natural heart acceleration signal, the processor selecting at least one lime segment of the natural heart acceleration signal to process; and a therapy delivery device connected to deliver therapy to the patient based on the processed time segment of the natural heart acceleration signal, wherein the at least one time segment is an isovolumetric phase of the patient'"'"'s cardiac cycle. - View Dependent Claims (35, 36, 37)
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38. An apparatus for providing therapy to a patient'"'"'s heart comprising:
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a natural heart acceleration sensor sized for implantation within the right ventricle of the patient'"'"'s heart; a signal generator coupled to the acceleration sensor and operative to generate a signal representative of the natural heart acceleration; a processor coupled to receive the natural heart acceleration signal, the processor selecting at least one time segment of the natural heart acceleration signal to process; a therapy delivery device connected to deliver therapy to the patient based on the processed time segment of the natural heart acceleration signal; and an ECG sensor of the patient and a signal generator for generating a signal representative of the ECG, and wherein the selection of the at least one time segment of the natural heart acceleration signal is based on a predetermined portion of the ECG signal. - View Dependent Claims (39, 40, 41, 42, 43, 44)
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45. An apparatus for providing therapy to a patient'"'"'s heart comprising:
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a natural heart acceleration sensor sized for implantation within the right ventricle of the patient'"'"'s heart; a signal generator coupled to the acceleration sensor and operative to generate a signal representative of the natural heart acceleration; a processor coupled to receive the natural heart acceleration signal, the processor selecting at least one time segment of the natural heart acceleration signal to process; a therapy delivery device connected to deliver therapy to the patient based on the processed time segment of the natural heart acceleration signal; and a heart beat rate sensor of the patient and a processor coupled to the sensor for varying the length of the selected time segment of the natural heart acceleration signal based on the heart beat rate. - View Dependent Claims (46, 47)
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48. A method of determining the contractile function of a patient'"'"'s heart comprising:
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implanting an acceleration sensor in the right ventricle of the patient'"'"'s heart; sensing a natural heart acceleration of the heart; generating a signal representative of the natural heart acceleration; selecting at least one time segment of the natural heart acceleration signal generally comprising an isovolumetric phase of the cardiac cycle; and processing the selected time segment of the signal to provide an indication of the contractile function of the heart. - View Dependent Claims (49, 50, 51, 52, 53, 54, 55, 56)
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57. An apparatus for determining the contractile function of a patient'"'"'s heart comprising:
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a natural heart acceleration sensor sized for implantation within the right ventricle of the patient'"'"'s heart; an ECG sensor; and a processor operably coupled to the natural heart acceleration sensor and the ECG sensor, the processor being operative to generate a first signal indicative of natural heart acceleration and a second signal indicative of ECG and to select at least one time segment of the natural heart acceleration signal based on a predetermined portion of the ECG signal, the at least one time segment being processed to provide an indication of contractile function of the patient'"'"'s heart. - View Dependent Claims (58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68)
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Specification