Anti-infective polymer-iodine coating for blood collection and delivery systems

• US 5,695,458 A
• Filed: 05/01/1996
• Issued: 12/09/1997
• Est. Priority Date: 02/27/1991
• Status: Expired due to Fees

• Current Assignee: Maryland Biopolymer Technologies, LLC
• Original Assignee: Maryland Biopolymer Technologies, LLC
• Inventors: Domb, Abraham J., Shikani, Alan H.
• Primary Examiner(s): Weiss, John G.
• Assistant Examiner(s): O YONG, KI
• Application Number:
  US08/641,518
• Time in Patent Office: 587 Days
• Field of Search: 604/4-6, 604/264, 604/280, 604/265, 128/207.14, 128/207.15, 623/1, 623/11, 623/12, 422/28, 422/40, 422/41, 427/2.12
• US Class Current: 604/4.01
• CPC Class Codes: A61L 2300/106 Halogens or compounds thereof, e.g. iodine, chlorite
• CPC Class Codes: A61L 2300/202 with halogen atoms, e.g. triclosan, povidone-iodine
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/606 Coatings
• CPC Class Codes: A61L 29/08 Materials for coatings
• CPC Class Codes: A61L 29/085 Macromolecular materials
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61L 31/08 Materials for coatings
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: A61M 2025/0056 provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
• CPC Class Codes: A61M 39/08 Tubes; Storage means specially adapted therefor
• CPC Class Codes: C08L 75/04 Polyurethanes

Abstract

A body fluid collection, storage and transfusion system which contains a polymer-iodine coating to destroy toxic microorganisms. The system is intended to be used to disinfect blood or blood products, as well as urine, wound exudates, serum, plasma, drainage fluids and synovial fluids.

Claims

1. A method for the safe and effective collection, storage and transfusion of blood comprising the steps of,

collecting blood from a donor into a polymer-iodine coated container to receive said blood,

storing said collected blood in a polymer-iodine coated storage container prior to transfusion, and then

transfusing into a recipient the blood from a polymer-iodine coated transfusion container, wherein the iodine released from each polymer-iodine coated container aids in inactivating toxic microorganisms in said blood.

2. The method of claim 1, wherein the iodine is removed from the stored blood prior to the transfusing.