Cardiac assist device having circadian muscle simulation

• US 5,697,884 A
• Filed: 08/17/1995
• Issued: 12/16/1997
• Est. Priority Date: 08/17/1995
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Neisz, Johann J., Francischelli, David, Gealow, Kendra K., Hammargren, John
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US08/516,086
• Time in Patent Office: 852 Days
• Field of Search: 600/16, 600/17, 607/1, 607/2, 607/48
• US Class Current: 600/17
• CPC Class Codes: A61N 1/36042 of grafted tissue, e.g. skeletal muscle
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

A cardiac assist device having circadian muscle stimulation. In particular the present invention operates in one of two states, either day mode or night mode. During the day mode, muscle stimulation and conditioning are performed according to a first schedule. During the night mode, muscle stimulation and conditioning are performed according to a second schedule. In addition, the night mode is only reached if the night mode is permitted, a set number of sensed beats are less than the night mode rate, and the time of day is nighttime. The night mode is interrupted if the night mode is turned off, the time of day is daytime, or a set number of beats are greater than the night rate. In short, the present invention provides for skeletal muscle stimulation at a less fatiguing level during the night than during the day.

Claims

1. A cardiac assist apparatus for assisting the mechanical contraction of a human heart, said apparatus including a surgically prepared skeletal muscle adapted to be mechanically coupled to the human heart, said apparatus comprising:

a twenty-four hour clock, the clock indicating a first time period and a second period;

means for delivering a first type of stimulation to the surgically prepared skeletal muscle when the clock indicates the first period;

means for delivering a second type of stimulation to the surgically prepared skeletal muscle when he clock indicates the second period;

wherein the means for delivering the first type of stimultion to the surgically prepared skeletal muscle comprises means for synchronizing a first burst of electrical pulses synchronized to a first number of heart beats;

a

wherein the means for delivering the second type of stimulation to the surgically prepared skeletal muscle comprises means for synchronizing a second burst of electrical pulses synchronized to a second number of heart beats.

2. The apparatus of claim 1 wherein the means for delivering the first type of stimulation to the surgically prepared skeletal muscle comprises means for synchronizing a first burst of electrical pulses having a first interpulse interval.

3. The apparatus of claim 1 wherein the means for delivering the second type of stimulation to the surgically prepared skeletal muscle comprises means for synchronizing a second burst of electrical pulses having a second interpulse interval.

4. A system for providing cardiac assistance, said apparatus including a surgically prepared skeletal muscle adapted to be mechanically coupled to a portion of the circulatory system, said apparatus comprising:

an implantable pulse generator adopted to be coupled to a heart and the skeletal muscle, the pulse generator further having a clock, the clock indicating either a first mode or second mode, the pulse generator having means for providing a first type of muscle stimulating pulse trains when the clock indicates the first mode and a second type of muscle stimulating pulse trains when the clock indicates the second mode; and

means for synchronizing the first type of muscle stimulating pulse trains to a first number of heart beats and means for synchronizing the second type of muscle stimulating pulse trains to a second number of heart beats.

5. The system of claim 4 further comprising means for synchronizing the first type of muscle stimulating pulse trains to every second heart bean and means for synchronizing the second type of muscle stimulating pulse trains to every fourth heart beat.

6. The system of claim 4 wherein the first type of muscle stimulating pulse trains are synchronized to every third heart beat and the second type of muscle stimulating pulse trains are synchronized to every fifth beat.

7. The system of claim 4 wherein the clock is a twenty-four hour clock.