Drug eluting stent
First Claim
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1. A method for delivery of a therapeutic substance to the interior of a body lumen comprising the steps of:
- (a) providing a generally cylindrical stent body;
(b) applying to the stent body a first layer which is a solid composite of polymer and therapeutic substance;
(c) applying fibrin over the composite;
(d) introducing the stent transluminally into a selected portion of the body lumen; and
(e) radially expanding the stent into contact with the body lumen.
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Abstract
An intraluminal stent comprising fibrin and an elutable drug is capable of providing a treatment of restenosis.
465 Citations
19 Claims
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1. A method for delivery of a therapeutic substance to the interior of a body lumen comprising the steps of:
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(a) providing a generally cylindrical stent body; (b) applying to the stent body a first layer which is a solid composite of polymer and therapeutic substance; (c) applying fibrin over the composite; (d) introducing the stent transluminally into a selected portion of the body lumen; and (e) radially expanding the stent into contact with the body lumen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for delivery of a therapeutic substance to an interior of a body lumen comprising the steps of:
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(a) providing a generally cylindrical stent having a body, said body having applied thereto a first layer which is a solid composite of polymer and therapeutic substance and a layer of fibrin as a second layer over the composite; (b) introducing the stent transluminally into a selected portion of the body lumen; and (c) radially expanding the stent into contact with the body lumen. - View Dependent Claims (15, 16, 17, 18, 19)
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Specification