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Fourier detection of species migrating in a microchannel

  • US 5,699,157 A
  • Filed: 07/16/1996
  • Issued: 12/16/1997
  • Est. Priority Date: 07/16/1996
  • Status: Expired due to Term
First Claim
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1. A microfluidic system for high-speed electrophoretic analysis of subject materials, said system comprisinga channel in a substrate, said channel holding said subject materials in solution in an electric field so that said materials move through said channel and separate into species bands according to species;

  • a light source exciting fluorescent light in said bands;

    a photoreceptor arranged to receive said fluorescent light from said bands;

    means for masking said channel so that said photoreceptor can receive said fluorescent light only at periodically spaced regions along said channel; and

    an unit connected to analyze frequencies of light intensity received by said photoreceptor so that velocities of said bands along said channel can be determined for analysis of said materials.

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