EEG operative and post-operative patient monitoring system and method

• US 5,699,808 A
• Filed: 03/07/1996
• Issued: 12/23/1997
• Est. Priority Date: 02/07/1994
• Status: Expired due to Term

• Current Assignee: New York University
• Original Assignee: New York University
• Inventors: John, Erwin Roy
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): YARNELL, BRYAN KEITH
• Application Number:
  US08/612,094
• Time in Patent Office: 656 Days
• Field of Search: 128/670, 128/731, 128/732
• US Class Current: 600/483
• CPC Class Codes: A61B 2505/05 Surgical care
• CPC Class Codes: A61B 5/1106 to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/383 Somatosensory stimuli, e.g. electric stimulation
• CPC Class Codes: A61B 5/4821 Determining level or depth of anaesthesia A61B5/1106 takes precedence
• CPC Class Codes: A61B 5/6814 Head

Abstract

An electrocephalograph (EEG) system and. method is provided to monitor patients during and after medical operations. An anesthesiologist administers sufficient anesthetics to cause the patient to attain the desired plane of anesthesia. The patient'"'"'s brain waves, both ongoing and evoked by stimuli, are amplified, digitized and recorded. That pre-operative set of brain wave data is compared to a set of the patient'"'"'s brain wave data obtained during the operation in order to determine if additional, or less, anesthesia is required, paying particular attention to the relative power in the theta band, as an indication of brain blood flow, and prolongations of the latency periods under brain stem stimuli, as an indication of the patient'"'"'s ability to feel pain.

Claims

1. A method for simultaneously monitoring a plurality of patients comprising:

(a) removably connecting a set of EEG electrodes to the scalp of each patient and a set of EKG electrodes and a blood pressure sensor to the body of each patient;

(b) presenting a set of stimuli to each patient and amplifying and digitizing the brain wave evoked responses to the stimuli and the patient'"'"'s ongoing irain wave activity collected from the EEG electrodes to provide a first set of EEG, EKG and blood pressure digital data representing each patient'"'"'s brain waves, heart activity and blood pressure in the patient'"'"'s first state and recording the first set of digital data in computer system memory;

(c) subsequently presenting the same set of stimuli to each patient and amplifying and digitizing the brain wave responses to the stimuli and the patient'"'"'s on-going brain wave activity and heart activity and blood pressure to provide a second set of digital data for each patient;

(d) using the computer system to statistically compare the first and second sets of digital data for each patient on a feature-by-feature basis and providing a warning if a combined multi-variant measure is abnormal by being of a difference between the first and second sets of digital data larger than a selected range of differences.

2. The method of claim 1 wherein the stimuli are auditory and the evoked responses are brain stem auditory responses (Brainstem Auditory Evoked Response).

3. The method of claim 1 wherein the stimuli are electrical or tactile and the evoked responses are brainstem somatosensory evoked responses (BSER).

4. The method of claim 1 wherein a plurality of electrodes are employed.

5. The method of claim 1 wherein the measures of the ongoing EEG include absolute and relative power in the delta, theta, alpha and beta bands.

6. The method of claim 1 wherein the warning is a visual signal on a computer system monitor screen or a toner signal.

7. The method of claim 1 wherein the statistical comparison for each patient is shown as a window on a video monitor display.