Vial having resealable membrane assembly activated by a medical delivery device

• US 5,702,019 A
• Filed: 09/27/1995
• Issued: 12/30/1997
• Est. Priority Date: 09/27/1995
• Status: Expired due to Term

• Current Assignee: Becton Dickinson France (Becton, Dickinson & Co)
• Original Assignee: Becton Dickinson France (Becton, Dickinson & Co)
• Inventors: Grimard, Jean Pierre
• Primary Examiner(s): Shoap, Allan N.
• Assistant Examiner(s): ELOSHWAY, NIKI MARINA
• Application Number:
  US08/534,754
• Time in Patent Office: 825 Days
• Field of Search: 215/301, 215/299, 215/307, 215/310, 215/231, 215/329, 215/270, 215/275, 215/302, 215/350, 215/DIG. 3, 220/367.1, 220/368, 220/254, 220/203.07, 220/203.11, 220/203.15-17, 604/411, 604/412, 604/413, 604/414, 604/415, 604/416, 604/89, 604/90, 604/91, 128/760, 141/23, 141/24, 141/26, 141/27, 141/312, 141/319, 141/349, 141/350, 141/383, 141/386
• US Class Current: 215/301
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: Y10S 215/03 Medical

Abstract

A resealable assembly for a container such as a bottle or vial featuring a membrane for selectively opening or sealing a fluid path between the bottle and a medical delivery device introduced into the assembly. The assembly includes a body disposed on said bottle, and a luer connector hub which may be separately provided with the body or formed integrally therewith. The luer connector hub features a connector end open for access by the medical delivery device, and an opposed end which is disposed for fluid communication with the open top of the bottle. A membrane, preferably formed from an elastomeric material, is secured across both the opposed end of the luer connector hub and the open top of the bottle, and may be retained between the top surface of the bottle and the body. The membrane preferably includes a central area sealing the opposed end of the luer connector hub from the open top of the bottle, with one or more fluid openings defined on a portion of the membrane outside of the central area. A force exerted on the central area by the medical delivery device deflects the membrane towards the interior of the vial, urging the membrane from sealing contact with the body and, hence, opening the fluid path between the interior of the bottle and the medical delivery device. The central area may display one or more fluid flow channels to facilitate fluid flow between the medical delivery device and the bottle as contact is made between the medical delivery device and the central area of the membrane. A sealing rib may be provided around a portion of the periphery of the luer connector hub to enhance sealing contact between the membrane and the luer connector hub.

Claims

1. A resealable container assembly accessible by a medical delivery device and providing a resealable fluid path between the medical delivery device and the container, comprising:

a container having an open top and a top surface disposed around portions of the container surrounding said open top;

a body disposed adjacent the top surface of the container;

means for communicating fluids with the container, said means having an end configured for introduction of the medical delivery device and an opposed end disposed on said body; and

a membrane disposed between the open top of said container and the opposed end of the means for communicating, said membrane having a central area disposed for contact with the medical delivery device and having a width at least equal to the width defined by the opposed end of the means for communicating, said central area comprising at least one fluid flow channel, said membrane having at least one fluid passage located outside said central area for fluid communication, via said at least one fluid flow channel between the medical delivery device introduced into the means for communicating and the open top of the container, and said membrane defining a sealing portion between said central area and said at least one fluid passage for sealing contact with the body,

wherein upon contact between said medical delivery device and the central area, said membrane is displaced to an open position, wherein said membrane is urged away from said sealing contact with the body to open the fluid path between the medical delivery device and the container.

2. The reseatable container assembly of claim 1, wherein said means for communicating comprises a luer connector hub.

3. The resealable container assembly of claim 2, further comprising an external seal for sealing the connector end of the luer connector hub.

4. The resealable container assembly of claim 3, wherein said external seal comprises a luer connector seal having a top wall and an annular side wall projecting from said top wall, said annular side wall including an array of internal threads selectively engageable with the connector end of said luer connector hub, and a seal disposed between said top wall and the connector end of the luer connector hub for sealingly engaging said connector end.

5. The resealable container assembly of claim 2, wherein said at least one fluid passage comprises a slit.

6. The resealable container assembly of claim 1 wherein said at least one fluid flow channel comprises spaces defined between raised protrusions provided on said central area.

7. The resealable container assembly of claim 1, wherein said at least one fluid flow channel comprises one or more troughs formed on the surface of the central area.

8. The resealable container assembly of claim 1, further comprising a sealing rib disposed about at least a portion of the periphery of said opposed end of the means for communicating, said sealing rib disposed for said sealing contact with said membrane when said membrane is in the closed position.

9. The resealable container assembly of claim 8, wherein when said medical delivery device displaces said membrane to the open position, said membrane is urged from sealing contact with said sealing rib to create a gap between the membrane and the sealing rib, thereby opening the fluid path between the medical delivery device and the open top of the container.

10. The resealable container assembly of claim 8, wherein said sealing rib comprises a rib having a square cross-section.

11. The resealable container assembly of claim 8, wherein said sealing rib comprises a rib having a peaked cross-section.

12. The resealable container assembly of claim 8, wherein said sealing rib comprises a rib having a rounded cross-section.

13. The resealable container assembly of claim 1, wherein said body and said means for communicating are formed as a unitary component.

14. The resealable container assembly of claim 1, wherein said body and said top surface are formed as a unitary component.

15. The resealable container assembly of claim 14, wherein said membrane comprises an elastomeric element supported between said body and the top surface of the bottle.

16. The reseatable container assembly of claim 1, wherein said membrane comprises an elastomeric element.

17. The reseatable container assembly of claim 1, wherein said membrane comprises an elastomeric element supported between said body and the top surface of the container.

18. The resealable container assembly of claim 1, further comprising a plurality of sealing ribs disposed about at least a portion of the periphery of said opposed end of the means for communicating for sealing contact with said membrane in the closed position.

19. The resealable container assembly of claim 1, further comprising a sealing rib disposed on said membrane for contact with said body outside of the periphery of the opposed end of the means for communicating.

20. The resealable container assembly of claim 1, wherein the container comprises an annular rim disposed about the open top of the container, said annular rim defining said top surface.

21. The resealable container assembly of claim 20, further comprising a crimp cap for securing said body to said annular rim.

22. The resealable container assembly of claim 1, wherein said at least one fluid passage comprises an opening.

23. The resealable container assembly of claim 1, wherein said body comprises a portion insertable through the open top of the bottle, said membrane comprising an elastomeric element extended across the opposed end of the means for communicating and the open top of the bottle.

24. A resealable container assembly accessible by a medical delivery device and providing a resealable fluid path between the medical delivery device and the container, comprising:

a bottle having an open top and a top surface disposed around portions of the container surrounding said open top;

a body disposed adjacent the top surface of the container;

a luer connector hub for communicating fluids with the container, said luer connector hub having a connector end configured for introduction of the medical delivery device and an opposed end disposed on said body, a plurality of ribs provided about the periphery of the opposed end; and

a membrane disposed between the open top of said container and the opposed end of the means for communicating, said membrane having a central area disposed for contact with the medical delivery device and having a width at least equal to the width defined by the opposed end of the means for communicating, said membrane having at least one fluid passage located outside said central area for fluid communication between the medical delivery device introduced into the luer connector hub and the open top of the container, and said membrane defining a sealing portion between said central area and said at least one fluid passage for sealing contact with the plurality of ribs provided on the opposed end of the luer connector hub,

wherein upon contact between said medical delivery device and the central area, said membrane is displaced to an open position, wherein said membrane is urged away from sealing contact with the body to open the fluid path between the medical delivery device and the container.

25. A resealable container assembly accessible by a medical delivery device and providing a resealable fluid path between the medical delivery device and the container, comprising:

a bottle having an open top and a top surface disposed around portions of the container surrounding said open top;

a body disposed adjacent the top surface of the container;

a luer connector hub for communicating fluids with the container, said luer connector hub having a connector end configured for introduction of the medical delivery device and an opposed end disposed on said body; and

a membrane disposed between the open top of said container and the opposed end of the means for communicating, said membrane having a central area disposed for contact with the medical delivery device and having a width at least equal to the width defined by the opposed end of the means for communicating, said membrane having at least one fluid passage located outside said central area for fluid communication between the medical delivery device introduced into the luer connector hub and the open top of the container, and said membrane defining a plurality of sealing ribs between said central area and said at least one fluid passage for sealing contact with the body,

wherein upon contact between said medical delivery device and the central area, said membrane is displaced to an open position, wherein the plurality of sealing ribs of said membrane are urged away from sealing contact with the body to open the fluid path between the medical delivery device and the container.