Method and devices for performing vascular anastomosis

• US 5,702,412 A
• Filed: 10/03/1995
• Issued: 12/30/1997
• Est. Priority Date: 10/03/1995
• Status: Expired due to Fees

• Current Assignee: Cedars-Sinai Medical Center (Cedars Sinai Health System)
• Original Assignee: Cedars-Sinai Medical Center (Cedars Sinai Health System)
• Inventors: Barath, Peter, Popov, Alexander
• Primary Examiner(s): LEWIS, WILLIAM W
• Application Number:
  US08/538,575
• Time in Patent Office: 819 Days
• Field of Search: 606/1, 606/159, 606/150, 606/152, 606/153, 606/170, 606/180, 607/126, 607/127, 607/131, 128/899
• US Class Current: 606/159
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 17/32053 Punch like cutting instruments, e.g. using a cylindrical or oval knife A61B17/326 takes precedence; trepans A61B17/1695; for use on the cornea A61F9/007
• CPC Class Codes: A61B 2017/1103 Approximator
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61B 2017/1135 End-to-side connections, e.g. T- or Y-connections Y-shaped blood vessel prostheses A61F2002/065
• CPC Class Codes: A61B 2017/320064 with tissue or sample retaining means
• CPC Class Codes: A61M 25/0127 Magnetic means; Magnetic markers

Abstract

A method and devices are provided for performing end-to-side anastomoses between the severed end of a first hollow organ and the side-wall of a second hollow organ utilizing transluminal approach with endoscopic assistance. In particular, the method utilizes a catheter, having a selectively operable cutter, which is introduced into the first hollow organ until the distal end of the catheter is substantially adjacent to the severed end of the first hollow organ. The severed end of the first hollow organ is positioned in proximity to the site for anastomoses on the side wall of the second hollow organ and the severed end is secured in sealing engagement with the side-wall, thereby defining a region of securement on the side wall of the second hollow organ. The severed end of the first hollow organ is preferably secured to the side wall of the second hollow organ by activating a corkscrew element in the catheter to penetrate the side-wall of the second hollow organ and hold the severed end of the first hollow organ in mating engagement with the side-wall of the second hollow organ. A plurality of clips can be applied to the seam between the first hollow organ and the second hollow organ. Alternatively, the first and second hollow organs can be secured by suturing. The cutter is then activated to remove a portion of the side-wall of the second hollow organ, thereby creating an opening within the region of securement and establishing the anastomosis.

Claims

1. A catheter for performing an end-to-side anastomosis between a severed end of a first hollow organ and a side-wall of a second hollow organ of a patient, comprising:

an elongated body having proximal and distal ends and adapted for introduction into and through the first hollow organ; and

a selectively operable cutter disposed within the body and having a cutting surface at the distal end which is configured to remove a portion of a side-wall of the second hollow organ.

2. The catheter of claim 1, wherein the distal end of the catheter defines a bore having an aperture in the distal end of the catheter and the cutter is disposed within the bore.

3. The catheter of claim 1, wherein the cutter includes:

an elongated cutter body disposed axially within the elongated catheter body and extendable along a longitudinal axis of the elongated catheter body; and

a cutting element associated with the elongated cutter body and configured for engagement with the second hollow organ.

4. The catheter of claim 3, wherein the catheter further includes a controller adapted to control the cutter.

5. The catheter of claim 1, wherein the catheter further includes a corkscrew element adapted to engage the side-wall of the second hollow organ whereby the severed end of the first hollow organ is held in mating engagement with the side-wall of the second hollow organ.

6. The catheter of claim 5, wherein the catheter further includes a controller adapted to control the corkscrew element.

7. The catheter of claim 6, wherein the controller includes a control wire disposed within the elongated body and movable along the longitudinal axis of the body of the catheter, the control wire further being connected to a control handle at the proximal end of the catheter and to the at the distal end of the catheter.

8. The catheter of claim 5, wherein the proximate end of the catheter includes a first controller adapted to control the corkscrew element and a second controller adapted to control the cutter.

9. A method for establishing an end-to-side anastomosis between a severed end of a first hollow organ and a side-wall of a second hollow organ, the method comprising:

(a) introducing a catheter, having proximal and distal ends, into the first hollow organ and passing the catheter through the first organ until the distal end of the catheter is substantially adjacent to the severed end of the first hollow organ, the catheter having a selectively operable cutter adapted to remove a portion of the side-wall of the second hollow organ;

(b) positioning the severed end of the first hollow organ in proximity with the site for anastomosis of the second hollow organ;

(c) securing the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, thereby defining a region of securement on a side-wall of the second hollow organ; and

(d) activating the cutter to remove a portion of a side-wall of the second hollow organ thereby creating an opening within the region of securement defined by the engagement of the severed end of the first hollow organ with the side-wall of the second hollow organ.

10. The method of claim 9, wherein the first and second hollow organs are both vascular lumens.

11. The method of claim 9, wherein the first hollow organ is the left internal mammary artery and the second hollow organ is a coronary artery.

12. The method of claim 11, wherein the catheter is first introduced into and through the femoral artery.

13. The method of claim 11, wherein the catheter is first introduced into and through the brachial artery.

14. The method of claim 9, wherein the method further includes:

generating an area of negative pressure in the interior of the catheter near the severed end, thereby engaging the side-wall of the coronary artery with the severed end of the Left Interior Mammary Artery.

15. The method of claim 9, wherein the securing of the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, includes stapling the first hollow organ to the sidewall of the second hollow organ.

16. The method of claim 9, wherein the securing of the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, includes suturing the first hollow organ to the sidewall of the second hollow organ.

17. A method for performing end-to-side anastomosis between a severed end of a first hollow organ and a side-wall of a second hollow organ, the method comprising:

(a) introducing a catheter, having proximal and distal ends, into the first hollow organ and passing the catheter through the first organ until the distal end of the catheter is substantially adjacent to the severed end of the first hollow organ, the catheter having a corkscrew element and a selectively operable cutter adapted to remove a portion of the side-wall of the second hollow organ;

(b) positioning the severed end of the first hollow organ in proximity with the site for anastomosis of the second hollow organ;

(c) activating the corkscrew element whereby corkscrew element penetrates the side wall of the severed hollow organ and the severed end of the first hollow organ is held in mating relationship with the second hollow organ;

(d) securing the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, thereby defining a region of securement on a side-wall of the second hollow organ; and

(e) activating the cutter to remove a portion of a side-wall of the second hollow organ thereby creating an opening within a region of securement defined by the engagement of the severed end of the first hollow organ with the side-wall of the second hollow organ.

18. The method of claim 17, wherein the first and second hollow organs are both vascular lumens.

19. The method of claim 17, wherein the first hollow organ is the left internal mammary artery and the second hollow organ is a coronary artery.

20. The method of claim 17, wherein the catheter is first introduced into and through the femoral artery.

21. The method of claim 17, wherein the catheter is first introduced into and through the brachial artery.

22. The method of claim 17, wherein the method further includes:

generating an area of negative pressure in the interior of the catheter near the severed end, thereby engaging the side-wall of the coronary artery with the severed end of the LIMA.

23. The method of claim 17, wherein the securing of the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, includes stapling the first hollow organ to the side-wall of the second hollow organ.

24. The method of claim 17, wherein the stage of securing the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, includes suturing the first hollow organ to the side-wall of the second hollow organ.

25. A method for performing a coronary bypass by establishing an end-to-side anastomosis between an arterial source of oxygenated blood and a coronary artery having a stenosis, the method comprising:

(a) introducing a catheter, having proximal and distal ends, into the arterial source and passing the catheter through the arterial source until the distal end of the catheter is substantially adjacent to the severed end of the arterial source, the catheter having a selectively operable cutter adapted to remove a portion of the side-wall of the coronary artery;

(b) severing the arterial source;

(c) positioning the severed end of the arterial source in proximity with the site for anastomosis of the coronary artery;

(d) securing the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, thereby defining a region of securement on a side-wall of the second hollow organ;

(e) activating the cutter to remove a portion of a side-wall of the coronary artery thereby creating an opening within the region of securement defined by the engagement of the severed end of the arterial source with the side-wall of the coronary artery.

26. The method of claim 25, wherein the first and second hollow organs are both vascular lumens.

27. The method of claim 25, wherein the first hollow organ is the left internal mammary artery and the second hollow organ is a coronary artery.

28. The method of claim 25, wherein the catheter is first introduced into and through the femoral artery.

29. The method of claim 25, wherein the catheter is first introduced into and through the brachial artery.

30. The method of claim 25, wherein the method further includes:

generating an area of negative pressure in the interior of the catheter near the severed end, thereby engaging the side-wall of the coronary artery with the severed end of the Left Interior Mammary Artery.

31. The method of claim 25, wherein the stage of securing the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, includes stapling the first hollow organ to the side-wall of the second hollow organ.

32. The method of claim 25, wherein the stage of securing the severed end of the first hollow organ in sealing engagement with the side-wall of the second hollow organ, includes suturing the first hollow organ to the side-wall of the second hollow organ.

33. A method for performing coronary bypass by effecting an end-to-side anastomoses between a arterial source of oxygenated blood and a coronary artery, the method comprising:

(a) introducing a plurality of trocar ports through the intercostal spaces of a patient;

(b) performing gas dissection of the thoracic cavity;

(c) isolating an arterial source of oxygenated blood;

(d) severing the arterial source;

(e) introducing a catheter, having proximal and distal ends, into the arterial source and passing the catheter through the arterial source until the distal end of the catheter is substantially adjacent to the severed end of the arterial source, the catheter having a corkscrew element adapted to penetrate and secure the side wall of the coronary artery, and a selectively operable cutter adapted to remove a portion of the side-wall of the coronary artery;

(f) performing endoscopic dissection of the parietal pleura;

(g) opening the pericardial sac;

(h) isolating the coronary artery proximally and distally to the site for anastomosis;

(i) placing the severed end of the arterial source in proximity to the site of anastomosis;

(j) activating the corkscrew element whereby the severed end of the arterial source is held in mating relationship with the coronary artery;

(k) securing the severed end of the arterial source in sealing engagement with the side wall of the coronary artery;

(l) activating the cutter whereby a portion of the side wall of the coronary artery engaged by the corkscrew element is removed;

(m) removing the cutter catheter and the portion of the side wall engaged by the corkscrew element;

(n) closing the pericardial sac;

(o) removing the trocar ports; and

(p) evacuating the thoracic cavity.

34. The method of claim 33, wherein the stage of securing the severed end of the first hollow organ in sealing engagement with the side-wall of the coronary artery, includes stapling the first hollow organ to the side-wall of the second hollow organ.

35. The method of claim 33, wherein the stage of securing the severed end of the first hollow organ in sealing engagement with the side-wall of the coronary artery, includes suturing the first hollow organ to the side-wall of the second hollow organ.