Composite membrane and support assembly
First Claim
Patent Images
1. A composite membrane and support assembly, comprising:
- a semipermeable membrane;
a fiber member for supporting the semipermeable membrane, and;
a rigid perforated member for supporting the semipermeable membrane and the fiber member.
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Abstract
For treating a fluid sample for introduction to a mass spectrometer or other appropriate use, a composite membrane and support assembly allows analytes from a sample flow to permeate through a membrane free from the undesired background matrix. The composite membrane and support assembly comprises a semipermeable membrane, a fiber member for supporting the membrane, and a rigid perforated member for supporting the membrane and the fiber support.
138 Citations
51 Claims
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1. A composite membrane and support assembly, comprising:
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a semipermeable membrane; a fiber member for supporting the semipermeable membrane, and; a rigid perforated member for supporting the semipermeable membrane and the fiber member. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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46. A method for obtaining analytes from an analyte-containing fluid sample, comprising the steps of:
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exposing the analyte-containing fluid sample to a first side of a composite membrane and support assembly comprising a semipermeable membrane, a fiber member supporting the semipermeable membrane, and a rigid perforated member supporting said semipermeable membrane and said fiber support; and accepting analytes that have permeated through the semipermeable membrane, the fiber member, and the rigid perforated member, from a second side of the composite membrane and support assembly. - View Dependent Claims (47, 48, 49, 50)
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51. An analyte introducing device for allowing analytes from a fluid sample to be introduced to an ion source chamber of a mass spectrometer, comprising:
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a composite membrane and support assembly comprising a semipermeable membrane, a fiber member for supporting the semipermeable membrane, and a rigid perforated member for supporting the semipermeable membrane and the fiber member; a passage through which the fluid sample can flow past a first side of the composite membrane and support assembly; and a valve for alternately isolating a second side of the composite membrane and support assembly from, and exposing the second side of the composite membrane and support assembly to, a vacuum filled transfer passage.
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Specification