Needleless hypodermic jet injector

• US 5,704,911 A
• Filed: 12/08/1995
• Issued: 01/06/1998
• Est. Priority Date: 09/28/1992
• Status: Expired due to Term

• Current Assignee: H.N.S. International, Inc.
• Original Assignee: Equidyne Systems, Inc. (Mansfelder Metals Ltd.)
• Inventors: Parsons, James S.
• Primary Examiner(s): Buiz, Michael
• Assistant Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US08/569,873
• Time in Patent Office: 760 Days
• Field of Search: 604/68-72, 604/187, 604/218, 604/131, 604/133, 604/134, 604/135, 604/140, 604/141, 604/156, 604/157
• US Class Current: 604/72
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

A system is provided that is useful for a hypodermic jet injection of medication without piercing the skin with a needle. The system includes a spring actuated needleless hypodermic injector device for injecting medication through the skin. The injector device includes an ampule assembly having a chamber for holding liquid medication and an injector for receiving and mounting the ampule assembly. A plunger assembly, movable within the ampule chamber is used for drawing liquid medication into the ampule chamber and for ejecting liquid medication out from a chamber. The injector includes a spring actuated piston which provides a force to move the ampule assembly plunger and thereby force liquid medication to leave the chamber at such velocity that it can be hypodermically injected at an injection site. The system also includes a coupler for use on a medication vial for transferring medication to the ampule assembly. The system also includes a cocking/carrying case which automatically cocks an injector device when it is placed within the case, and the lid is closed.

Claims

1. A spring actuated needleless hypodermic jet injection system comprising:

an ampule assembly comprising;

a shell having a chamber for holding liquid medication between first and second ends of the shell;

an orifice in the first end of the shell and communicating with the chamber through which liquid medication is drawn into and ejected out from the chamber; and

a plunger assembly movable within the chamber for converting an applied force to a corresponding pressure applied to the liquid, the plunger assembly for drawing liquid medication into the chamber and for ejecting liquid medication out from the chamber;

an injector for receiving and mounting the ampule assembly and for providing said applied force to move the plunger assembly, the injector comprising;

a cylindrical housing having a front end, a back end, and defining a longitudinal channel therebetween, wherein the front end of the housing is open and configured to receive the second end of the ampule assembly;

a piston mounted for sliding movement in the longitudinal channel, the piston for applying said force to the plunger assembly;

a spring disposed within the channel and communicating with the piston, the spring for accumulating and storing a sufficient amount of energy when compressed to produce sufficient pressure to cause the liquid to leave the chamber via the orifice at such a velocity that it can be hypodermically injected at an injection site, wherein the energy is converted to said force by the piston when the spring is released;

a trigger assembly coupled to the spring for manually releasing the stored energy;

coupling means disposed in the open end of the injector housing for coupling the ampule assembly to the housing; and

a safety interlock assembly, coupled between the trigger assembly and the coupling means, the safety interlock operatively responsive to the ampule assembly as being coupled to the injector housing, the safety interlock assembly preventing release of the stored energy by the trigger assembly unless an ampule assembly is coupled to the injector.

2. The injection system according to claim 1 further comprising:

a syringe cartridge;

a liquid transfer unit including a loader assembly with a hollow tubular body, wherein the syringe cartridge is disposed within the body, the body having a base end defining a threaded opening, a jack screw for rotatably engaging the threaded opening, the jack screw communicating with the syringe cartridge to apply pressure to liquid within the cartridge when the jack screw is rotated; and

a transfer adapter connected to the tubular body at an end opposite the base end, the adapter including a cannula which extends into the tubular body and pierces the syringe cartridge, the transfer adapter including means for coupling to the first end of the ampule assembly, the orifice of the ampule assembly being thereby in communication with the adapter, wherein as the jack screw is rotated the liquid is forced from the syringe cartridge and into the ampule assembly through the orifice.

3. The injection assembly according to claim 1 further comprising a medication vial and a vial coupler including a shroud dimensioned to receive the medication vial therein, the vial coupler including a cannula which extends into the shroud and pierces the medication vial, the vial coupler including means for coupling to the first end of the ampule assembly, the orifice of the ampule assembly being in communication with the vial coupler.

4. The injection system according to claim 1 further comprising:

a cocking/carrying case having a cavity, wherein the injector is disposed within the cavity, the cocking/carrying case comprising;

a rectangular base and cover hingedly connected together at a short side such that the cover describes an arc when closed upon the base; and

cocking means operatively responsive to the closing of the cover, for engaging the injector to compress the spring to accumulate said suitable amount of energy.

5. The injector system according to claim 4, wherein the cocking/carrying case further comprises a shuttle slidably mounted on the base, the shuttle including a centrally mounted and longitudinally extending ramrod configured to extend into the open front end of the injector housing when the injector is disposed in the cavity, the ramrod bearing against the injector piston such that when the lid is closed, the ramrod exerts a force on the piston to thereby compress the spring to accumulate said suitable amount of energy.

6. The injection system according to claim 5, wherein the cocking/carrying case further comprises thrust means connected between the cover and the shuttle, the thrust means translating the arcuate motion of the cover into a lateral motion of the shuttle.

7. The injection system according to claim 1, the longitudinal channel further comprising means for varying the force of the spring acting on the piston to thereby vary the velocity of the medication as it is ejected through the ampule assembly orifice.

8. The injection system according to claim 1, wherein the plunger assembly includes a piston which slidably moves within the ampule chamber, the piston having a circumference, a front end including a front-facing surface and an indentation around the circumference at the front end such that a flange is formed at the front-facing surface of the piston.

9. An injection system according to claim 8, wherein the plunger assembly includes a handle connected to the piston and extending out of an opening in the second end of the ampule, the handle dimensioned for insertion into the front end of the injector housing and configured to be driven by the injector piston.

10. A spring actuated needleless hypodermic jet injection system comprising:

an ampule assembly comprising;

a shell having a chamber for holding liquid medication between first and second ends of the shell;

an orifice in the first end of the shell and communicating with the chamber through which liquid medication is drawn into and ejected out from the chamber; and

a plunger assembly movable within the chamber for converting an applied force to a corresponding pressure applied to the liquid, the plunger assembly for drawing liquid medication into the chamber and for ejecting liquid medication out from the chamber;

an injector for receiving and mounting the ampule assembly and for providing said applied force to move the plunger assembly, the injector comprising;

a cylindrical housing having a front end, a back end, and defining a longitudinal channel therebetween, wherein the front end of the housing is open and configured to receive the second end of the ampule assembly;

a piston mounted for sliding movement in the longitudinal channel, the piston for applying said force to the plunger assembly;

a spring disposed within the channel and communicating with the piston, the spring for accumulating and storing a sufficient mount of energy when compressed to produce sufficient pressure to cause the liquid to leave the chamber via the orifice at such a velocity that it can be hypodermically injected at art injection site, wherein the energy is converted to said force by the piston when the spring is released;

a trigger assembly coupled to the spring for manually releasing the stored energy;

coupling means disposed in the open end of the injector housing for coupling the ampule assembly to the housing; and

a cocking/carrying case having a base, a closable cover and a cavity, wherein the injector is disposed within the cavity, the cocking/carrying case including cocking means operatively responsive to the closing of the cover for engaging the injector to compress the spring to accumulate said suitable amount of energy.

11. The injector system according to claim 10, wherein the cocking/carrying case further comprises a shuttle slidably mounted on the base, the shuttle including a centrally mounted and longitudinally extending ramrod configured to extend into the open front end of the injector housing when the injector is disposed in the cavity, the ramrod bearing against the injector piston such that when the lid is closed, the ramrod exerts a force on the piston to thereby compress the spring to accumulate said suitable amount of energy.

12. The injection system according to claim 11, wherein the cocking/carrying case further comprises thrust means connected between the cover and the shuttle, the thrust means translating an arcuate closing motion of the cover into a lateral motion of the shuttle.

13. The injection system according to claim 12, further comprising:

a safety interlock assembly, coupled between the trigger assembly and the coupling means, the safety interlock operatively responsive to the ampule assembly'"'"'s as being coupled to the injector housing, the safety interlock assembly preventing release of the stored energy by the trigger assembly unless an ampule assembly is coupled to the injector; and

second safety means disposed on the injector housing and rotatably movable to be interposed between the trigger assembly and the injector housing to prevent the trigger from manually releasing the stored energy.

14. The injection system according to claim 10, the cylindrical housing further comprising&

means for varying the force of the spring acting on the piston to thereby vary the velocity of the medication as it is ejected through the ampule assembly orifice.

15. The injection system according to claim 10, wherein the plunger assembly includes a piston which slidably moves within the ampule chamber, the piston having a circumference, a front end including a front-facing surface and an indentation around the circumference at the front end such that a flange is formed at the front-facing surface of the piston.

16. An injection system according to claim 15, wherein the plunger assembly includes a handle connected to the piston and extending out of an opening in the second end of the ampule, the handle dimensioned for insertion into the front end of the injector housing and configured to be driven by the injector piston.

17. A spring actuated needleless hypodermic jet injection system comprising:

an ampule assembly comprising;

a shell having a chamber for holding liquid medication between first and second ends of the shell;

an orifice in the first end of the shell and communicating with the chamber through which liquid medication is drawn into and ejected out from the chamber; and

a plunger assembly movable within the chamber for converting an applied force to a corresponding pressure applied to the liquid, the plunger assembly for drawing liquid medication into the chamber and for ejecting liquid medication out from the chamber;

an injector for receiving and mounting the ampule assembly and for providing said applied force to move the plunger assembly, the injector comprising;

a cylindrical housing having a from end, a back end, and defining a longitudinal channel therebetween, wherein the front end of the housing is open and configured to receive the second end of the ampule assembly;

a piston mounted for sliding movement in the longitudinal channel, the piston for applying said force to the plunger assembly;

a spring disposed within the channel and communicating with the piston, the spring for accumulating and storing a sufficient amount of energy when compressed to produce sufficient pressure to cause the liquid to leave the chamber via the orifice at such a velocity that it can be hypodermically injected at an injection site, wherein the energy is converted to said force by the piston when the spring is released;

a trigger assembly coupled to the spring for manually releasing the stored energy;

coupling means disposed in the open end of the injector housing for coupling the ampule assembly to the housing;

a cocking/carrying case having a base, a closable cover and a cavity, wherein the injector is disposed within the cavity, the cocking/carrying case including cocking means operatively responsive to the dosing of the cover for engaging the injector to compress the spring to accumulate said suitable amount of energy; and

liquid transfer means for drawing liquid medication from a medication container into the ampule assembly through the orifice.

18. The injection system according to claim 17, the liquid transfer means further comprising:

a syringe cartridge;

a liquid transfer unit including a loader assembly with a hollow tubular body, wherein the syringe cartridge is disposed within the body, the body having a base end defining a threaded opening, a jack screw for rotatably engaging the threaded opening, the jack screw communicating with the syringe cartridge to apply pressure to liquid within the cartridge when the jack screw is rotated; and

a transfer adapter connected to the tubular body at an end opposite the base end, the adapter including a cannula which extends into the tubular body and pierces the syringe cartridge, the transfer adapter including means for coupling to the first end of the ampule assembly, the orifice of the ampule assembly being thereby in communication with the adapter, wherein as the jack screw is rotated the liquid is forced from the syringe cartridge and into the ampule assembly through the orifice.

19. The injection system according to claim 17, the liquid transfer means further comprising:

a medication vial and a vial coupler including a shroud dimensioned to receive the medication vial therein, the vial coupler including a cannula which extends into the shroud and pierces the medication vial, the vial coupler including means for coupling to the first end of the ampule assembly, the orifice of the ampule assembly being in communication with the vial coupler.

20. The injector system according to claim 17, wherein the cocking/carrying case further comprises a shuttle slidably mounted on the base, the shuttle including a centrally mounted and longitudinally extending ramrod configured to extend into the open front end of the injector housing when the injector is disposed in the cavity, the ramrod bearing against the injector piston such that when the lid is closed, the ramrod exerts a force on the piston to thereby compress the spring to accumulate said suitable amount of energy.

21. The injection system according to claim 20, wherein the cocking/carrying case further comprises thrust means connected between the cover and the shuttle, the thrust means translating an arcuate closing motion of the cover into a lateral motion of the shuttle.

22. The injection system according to claim 17, further comprising:

a safety interlock assembly, coupled between the trigger assembly and the coupling means, the safety interlock operatively responsive to the ampule assembly'"'"'s as being coupled to the injector housing, the safety interlock assembly preventing release of the stored energy by the trigger assembly unless an ampule assembly is coupled to the injector; and

second safety means disposed on the injector housing and rotatably movable to be interposed between the trigger assembly and the injector housing to prevent the trigger from manually releasing the stored energy.

23. The injection system according to claim 17, the cylindrical housing further comprising means for varying the force of the spring acting on the piston to thereby vary the velocity of the medication as it is ejected through the ampule assembly orifice.

24. The injection system according to claim 17, wherein the plunger assembly includes a piston which slidably moves within the ampule chamber, the piston having a circumference, a front end including a front-facing surface and an indentation around the circumference at the front end such that a flange is formed at the front-facing surface of the piston.

25. An injection system according to claim 24, wherein the plunger assembly includes a handle connected to the piston and extending out of an opening in the second end of the ampule, the handle dimensioned for insertion into the front end of the injector housing and configured to be driven by the injector piston.