Triple antimicrobial composition

• US 5,705,532 A
• Filed: 11/13/1995
• Issued: 01/06/1998
• Est. Priority Date: 11/13/1995
• Status: Expired due to Fees

• Current Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Original Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Inventors: Modak, Shanta, Sampath, Lester
• Primary Examiner(s): ROBINSON, ALLEN JAY
• Application Number:
  US08/556,256
• Time in Patent Office: 785 Days
• Field of Search: 514/635, 514/643, 514/737
• US Class Current: 514/635
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 31/08 Oxygen or sulfur directly attached to an aromatic ring system
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof

Abstract

The present invention relates to antimicrobial compositions comprising (i) less than or equal to two percent by weight chlorhexidine or chlorhexidine salt; (ii) less than or equal to 0.1 percent by weight of a quaternary ammonium compound such as benzalkonium chloride; and (iii) less than or equal to two percent by weight of parachlorometaxylenol. The antimicrobial compositions of the invention may be utilized in antimicrobial detergents, soaps, creams, rinses, and emulsions for use in the medical community as well as general public use.

Claims

1. An antimicrobial composition comprising synergistic effective amounts of (i) less than or equal to two percent of an antimicrobial agent selected from the group consisting of chlorhexidine and a chlorhexidine salt;

(ii) less than or equal to 0.1 percent of benzalkonium chloride; and

(iii) less than or equal to 2 percent parachlorometaxylenol.

2. The composition of claim 1, which comprises chlorhexidine.

3. The composition of claim 2, wherein the concentration of chlorhexidine is 2 percent by weight and the concentration of parachlorometaxylenol is 2 percent by weight.

4. An antimicrobic composition comprising synergistic effective amounts of (i) less than or equal to 2% of chlorhexidine gluconate;

(ii) less than or equal to 0.1% of benzalkonium chloride; and

(iii) less than or equal to 2% parachlorometaxylenol.