Integrated planar liquid handling system for maldi-TOF MS
First Claim
1. An integrated liquid handling system for a MALDI-TOF mass spectrometer comprising a thin film support having an upper surface and a lower surface, said upper surface including a sample handling compartment and said lower surface including means for moving an analyte and fluids within said compartment, wherein said sample handling compartment comprises:
- a reservoir for receiving fluid substances;
a MALDI ionization surface; and
a microchannel for interconnecting said reservoir and said ionization surface.
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Accused Products
Abstract
An integrated liquid sample handling system for matrix-assisted laser-desorption/ionization time-of-flight mass spectroscopy (MALDI-TF MS) is described. The integrated system comprises a miniaturized sample handling compartment containing a MALDI ionization surface for separating, chemically manipulating and detecting analytes by MALDI -TOF MS. The miniaturized integrated sample handling system disclosed herein is applicable to a wide range of analytical problems that require separation and/or chemical manipulation of a sample prior to mass analysis as part of the analytical procedure.
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Citations
9 Claims
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1. An integrated liquid handling system for a MALDI-TOF mass spectrometer comprising a thin film support having an upper surface and a lower surface, said upper surface including a sample handling compartment and said lower surface including means for moving an analyte and fluids within said compartment, wherein said sample handling compartment comprises:
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a reservoir for receiving fluid substances; a MALDI ionization surface; and a microchannel for interconnecting said reservoir and said ionization surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification