Polybutadiene-based compositions for contact lenses

• US 5,708,094 A
• Filed: 12/17/1996
• Issued: 01/13/1998
• Est. Priority Date: 12/17/1996
• Status: Expired due to Term

• Current Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Original Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Inventors: Lai, Yu-Chin, Bambury, Ronald E.
• Primary Examiner(s): ZEMEL, IRINA SOPJIA
• Application Number:
  US08/768,748
• Time in Patent Office: 392 Days
• Field of Search: 525/296, 525/298, 525/301, 525/302, 525/278, 525/279, 525/937, 523/106
• US Class Current: 525/296
• CPC Class Codes: C08F 290/048 Polymers of monomers having two or more carbon-to-carbon double bonds as defined in group C08F36/00
• CPC Class Codes: C08L 51/00 Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds for ABS polymers C08L55/02; Compositions of derivatives of such polymers
• CPC Class Codes: C08L 51/04 grafted on to rubbers
• CPC Class Codes: G02B 1/043 Contact lenses
• CPC Class Codes: Y10S 525/937 Utility as body contact e.g. implant, contact lens or I.U.D.

Abstract

Contact lenses are made from the polymerization product of a monomer mixture comprising a polybutadiene-based compound as represented by formula (I)

E--B(AB).sub.a --E                                         (I)

wherein:

A is selected from the group consisting of a chemical bond, --OCO--, --COO--, --CONH--, --NHCO--, --OCOO--, --NHCOO-- and --OCONH--,

a is zero or an integer of at least 1;

each B is independently represented by the formula (II) ##STR1## where each of m, n, and p is independently 0 or greater, provided that m+n+p is at least 10;

R is hydrogen or C₁ -C₄ alkyl;

each E is independently a polymerizable terminal ethylenically unsaturated organic group.

Claims

1. A contact lens formed from the polymerization product of a monomer mixture comprising a polybutadiene-based compound having the following structure

View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)

2. The contact lens of claim 1 wherein the monomer mixture further comprises a hydrophilic monomer.

3. The contact lens of claim 2 wherein the monomer mixture contains about 50 to about 80 weight percent of the polybutadiene-based compound of claim 1.

4. The contact lens of claim 2 wherein the monomer mixture contains about 60 to about 70 weight percent of the polybutadiene-based compound of claim 1.

5. The contact lens of claim 2 wherein the hydrophilic monomer includes at least one member selected from the group consisting of N,N- dimethylacrylamide, N-vinyl-2-pyrrolidone, 2-hydroxyethyl methacrylate, N-(2-hydroxyethyl)-methacrylamide, glyceryl methacrylate and methacrylic acid.

6. The contact lens of claim 2 wherein the monomer mixture further comprises a polymerization initiator.

7. The contact lens of claim 2 wherein the monomer mixture further comprises a crosslinking agent.

8. The contact lens of claim 1 wherein each E is ##STR14## wherein R² is hydrogen or methyl;

y is 0 or an integer of 1 to 6; and

v is 0 or 1.

9. The contact lens of claim 8 wherein each E is ##STR15##

10. The contact lens of claim 9, wherein the polybutadiene-based compound has the formula ##STR16## and a molecular weight of 2,000 to 15,000.

11. A hydrogel that is the hydrated polymerization product of a monomer mixture comprising the polybutadiene-based compound having the following structure

View Dependent Claims (12)

12. The hydrogel of claim 11 wherein the monomer mixture further comprises at least one hydrophilic monomer.