Method of generating a plurality of chemical compounds in a spatially arranged array
First Claim
1. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
- forming a plurality of molecular constructs having a scaffold backbone of a chemical molecule comprising a linear, branched or cyclic organic compound having at least three atoms of carbon, nitrogen, sulfur, phosphorus or combinations thereof, and at least one location on the molecule capable of undergoing reaction with other molecules for attachment of at least one structural diversity element;
laying out an array possessing a logical ordering of sub-arrays of said molecular constructs;
providing each sub-array with molecular constructs having said scaffold backbone and at least one structural diversity element which is different from the others; and
relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements.
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Accused Products
Abstract
A method for constructing an array of synthetic molecular constructs, by forming a plurality of molecular constructs having a scaffold backbone of a chemical molecule comprising a linear, branched or cyclic organic compound having at least atoms of carbon, nitrogen, sulfur, phosphorus, or combinations thereof, and at least one location on the molecule capable of undergoing reaction with other molecules for attachment of at least one structural diversity element; laying out an array possessing a logical ordering of sub-arrays of the molecular constructs; providing each sub-array with molecular constructs having the scaffold backbone and at least one structural diversity element which is different from the others; and relating each sub-array within the array to all other sub arrays by the difference in the structural diversity elements.
223 Citations
29 Claims
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1. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
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forming a plurality of molecular constructs having a scaffold backbone of a chemical molecule comprising a linear, branched or cyclic organic compound having at least three atoms of carbon, nitrogen, sulfur, phosphorus or combinations thereof, and at least one location on the molecule capable of undergoing reaction with other molecules for attachment of at least one structural diversity element; laying out an array possessing a logical ordering of sub-arrays of said molecular constructs; providing each sub-array with molecular constructs having said scaffold backbone and at least one structural diversity element which is different from the others; and relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 24, 27)
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13. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
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forming a plurality of molecular constructs having a scaffold backbone of the following structure;
##STR89## laying out an array possessing a logical ordering of sub-arrays of said molecular constructs;providing each sub-array with molecular constructs having said scaffold backbone and at least one structural diversity element which is different from the others; and relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements. - View Dependent Claims (18, 19, 20, 21, 22, 23, 25, 28)
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14. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
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forming a plurality of molecular constructs having a scaffold backbone of the following structure;
##STR90## laying out an array possessing a logical ordering of sub-arrays of said molecular constructs;providing each sub-array with molecular constructs having said scaffold backbone and at least one structural diversity element which is different from the others; and relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements.
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15. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
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forming a plurality of molecular constructs having a scaffold backbone of the following structure;
##STR91## laying out an array possessing a logical ordering of sub-arrays of said molecular constructs;providing each sub-array with molecular constructs having said scaffold backbone and at least one structural diversity element which is different from the others; and relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements.
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16. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
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forming a plurality of molecular constructs having a scaffold backbone of the following structure;
##STR92## laying out an array possessing a logical ordering of sub-arrays of said molecular constructs;providing each sub-array with molecular constructs having said scaffold backbone and at least one structural diversity element which is different from the others; and relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements.
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17. A method for constructing an array of synthetic molecular constructs, comprising the steps of:
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forming a plurality of molecular constructs; laying out an array possessing a logical ordering of sub-arrays of said molecular constructs; providing each sub-array with molecular constructs having the common molecular core ##STR93## and at least one structural diversity element which is different from the others, and; relating each sub-array within the array to all other sub arrays by said difference in said structural diversity elements. - View Dependent Claims (26, 29)
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Specification