Waterborne lubricant for teflon products

• US 5,712,229 A
• Filed: 12/09/1996
• Issued: 01/27/1998
• Est. Priority Date: 12/07/1995
• Status: Expired due to Fees

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Khan, Mohammad A., Hopkins, David P.
• Primary Examiner(s): Howard, Jacqueline V.
• Application Number:
  US08/762,360
• Time in Patent Office: 414 Days
• Field of Search: 508/202
• US Class Current: 508/202
• CPC Class Codes: A61B 2017/0084 low friction A61B2017/00853 takes precedence
• CPC Class Codes: A61M 2025/0046 Coatings for improving slidability
• CPC Class Codes: C10M 129/06 having hydroxy groups bound to acyclic or cycloaliphatic carbon atoms
• CPC Class Codes: C10M 129/20 Cyclic ethers having 4 or more ring atoms, e.g. furans, dioxolanes
• CPC Class Codes: C10M 133/06 having amino groups bound to acyclic or cycloaliphatic carbon atoms
• CPC Class Codes: C10M 133/22 containing a carbon-to-nitrogen double bond, e.g. guanidines, hydrazones, semicarbazones
• CPC Class Codes: C10M 149/14 a condensation reaction being involved
• CPC Class Codes: C10M 155/02 Monomer containing silicon
• CPC Class Codes: C10M 173/02 not containing mineral or fatty oils
• CPC Class Codes: C10M 2201/02 Water
• CPC Class Codes: C10M 2207/021 having hydroxy groups bound to acyclic or cycloaliphatic carbon atoms
• CPC Class Codes: C10M 2207/023 having hydroxy groups bound to carbon atoms of six-membered aromatic rings
• CPC Class Codes: C10M 2207/044 Cyclic ethers having four or more ring atoms, e.g. furans, dioxolanes
• CPC Class Codes: C10M 2207/281 of (cyclo)aliphatic monocarboxylic acids
• CPC Class Codes: C10M 2207/282 of (cyclo)aliphatic oolycarboxylic acids
• CPC Class Codes: C10M 2207/283 of polyhydroxy compounds
• CPC Class Codes: C10M 2207/286 of polymerised unsaturated acids
• CPC Class Codes: C10M 2211/042 Alcohols; Ethers; Aldehydes; Ketones
• CPC Class Codes: C10M 2211/06 Perfluorinated compounds
• CPC Class Codes: C10M 2215/04 having amino groups bound to acyclic or cycloaliphatic carbon atoms
• CPC Class Codes: C10M 2215/14 : Containing carbon-to-nitrogen double bounds, e.g. guanidines, hydrazones, semicarbazones
• CPC Class Codes: C10M 2215/26 : Amines
• CPC Class Codes: C10M 2217/041 : involving a condensation reaction
• CPC Class Codes: C10M 2217/042 : between the nitrogen-containing monomer and an aldehyde or ketone
• CPC Class Codes: C10M 2217/043 : Mannich bases
• CPC Class Codes: C10M 2229/02 : Unspecified siloxanes; Silicones
• CPC Class Codes: C10M 2229/04 : Siloxanes with specific structure
• CPC Class Codes: C10M 2229/041 : containing aliphatic substituents
• CPC Class Codes: C10M 2229/042 : containing aromatic substituents
• CPC Class Codes: C10M 2229/043 : containing carbon-to-carbon double bonds
• CPC Class Codes: C10M 2229/044 : containing silicon-to-hydrogen bonds
• CPC Class Codes: C10M 2229/045 : containing silicon-to-hydroxyl bonds
• CPC Class Codes: C10M 2229/046 : containing silicon-oxygen-carbon bonds
• CPC Class Codes: C10M 2229/047 : containing alkylene oxide groups
• CPC Class Codes: C10M 2229/048 : containing carboxyl groups
• CPC Class Codes: C10M 2229/05 : containing atoms other than silicon, hydrogen, oxygen or carbon
• CPC Class Codes: C10M 2229/051 : containing halogen
• CPC Class Codes: C10M 2229/052 : containing nitrogen
• CPC Class Codes: C10M 2229/053 : containing sulfur
• CPC Class Codes: C10M 2229/054 : containing phosphorus
• CPC Class Codes: C10N 2040/00 : Specified use or application for which the lubricating composition is intended
• CPC Class Codes: C10N 2040/30 : Refrigerators lubricants or compressors lubricants
• CPC Class Codes: C10N 2040/32 : Wires, ropes or cables lubricants
• CPC Class Codes: C10N 2040/34 : Lubricating-sealants
• CPC Class Codes: C10N 2040/36 : Release agents or mold release agents
• CPC Class Codes: C10N 2040/38 : Conveyors or chain belts
• CPC Class Codes: C10N 2040/40 : Generators or electric motors in oil or gas winning field
• CPC Class Codes: C10N 2040/42 : Flashing oils or marking oils
• CPC Class Codes: C10N 2040/44 : Super vacuum or supercritical use
• CPC Class Codes: C10N 2040/50 : Medical uses
• CPC Class Codes: C10N 2050/01 : Emulsions, colloids, or micelles

Abstract

This invention relates to a new water soluble lubricant for a medical device, such as a catheter and an introducer needle. The lubricant is a silicone surfactant which is non-ionic and which is a good lubricating fluid. Preferably the silicone surfactant that is used is a block copolymer polyalkylene oxide-modified polydimethylsiloxane. Water is used as the solvent for this lubricant. The lubrication solution includes a solution stabilizer to clarify the solution and antimicrobial agents to inhibit microbial growth in the water solution or on the coated product. Vitamin E or its derivatives may also be used in the lubrication solution. When the lubrication solution is used to lubricate Teflon products, a small amount of a low molecular weight alcohol is added to the lubrication solution to increase wettability.

Claims

1. A lubrication solution for a medical device, consisting essentially of:

about 2% to about 6% of a silicone surfactant lubricant;

less than about 30% of a low molecular weight alcohol; and

the balance water.

2. The lubrication solution of claim 1, wherein the silicone surfactant lubricant is a block copolymer polyalkene oxide-modified polydimethylsiloxane.

3. The lubrication solution of claim 1, wherein the silicone surfactant lubricant is an amino-modified silicone polyether copolymer.

4. The lubrication solution of claim 2 wherein the silicone surfactant lubricant also includes an amino-modified silicone polyether copolymer.

5. The lubrication solution of claim 1 wherein the low molecular weight alcohol has a molecular weight less than or equal to 150.