Method and apparatus for monitored biphasic cardiac impedance sensing

• US 5,713,935 A
• Filed: 08/23/1996
• Issued: 02/03/1998
• Est. Priority Date: 08/23/1996
• Status: Expired due to Term

• Current Assignee: Intermedics Incorporated
• Original Assignee: Sulzer Intermedics, Inc. (Sulzer AG)
• Inventors: Paul, Patrick J., Deno, D. Curtis, Prutchi, David
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/697,454
• Time in Patent Office: 529 Days
• Field of Search: 607/6, 607/8, 607/9, 607/24, 607/28, 128/697
• US Class Current: 607/28
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

A method and apparatus for monitoring balanced biphasic current pulses used for measuring impedance in cardiac stimulators involves detecting imbalances between the pulses of opposite polarity. Such imbalances are potentially harmful to cardiac stimulator users. By converting the two different pulse phases into potentials, a determination can be made as to whether adequately balanced pulses are being generated. If an imbalance is detected, corrective action can be taken quickly enough to avoid harmful effects to the stimulator user.

Claims

1. A cardiac stimulation apparatus comprising:

a stimulator for producing a stimulating pulse to stimulate a patient'"'"'s heart;

an impedance measuring circuit for measuring impedance within the patient'"'"'s body, said impedance measuring circuit including

a signal generator for producing a biphasic current pulse pair, said pulse pair having a first pulse having current flowing in a first direction and a second pulse having current flowing in a second direction, means for electrically transmitting said pulse pair through at least a portion of the patient'"'"'s body, and

means for determining impedance from said pulse pair;

means responsive to said impedance measuring circuit for controlling said stimulator;

a monitor comprising a test load for selectively receiving said pulse pair and means for comparing said first and second pulses when applied across said test load; and

means responsive to said monitor for controlling said impedance measuring circuit.

2. The apparatus of claim 1 wherein said monitor includes a circuit for generating voltage signals representative of the amplitude of both of said pulses of at least one pulse pair and wherein said means for comparing said first and second pulses includes means for comparing said voltage signals.

3. The apparatus of claim 2 including a first circuit for generating a first voltage signal representative of the amplitude of said first pulses and a second circuit for generating a second voltage signal of opposite polarity indicative of the amplitude of said second pulses and wherein said means for comparing said first and second pulses includes means for comparing said voltage signals.

4. The apparatus of claim 3 wherein said means for comparing includes a summer connected to said first and second circuits to add said first and second voltage signals and a comparator for comparing said first and second voltage signals to a predetermined standard.

5. The apparatus of claim 4 wherein said first and second voltage signals are also representative of the duration of said pulses.

6. The apparatus of claim 2 wherein said test load includes a capacitor connected to be in series with said portion of the patient'"'"'s body and said signal generator when said means for transmitting said pulse pair is connected to said patient'"'"'s body and wherein said means for comparing comprises a comparator connected in parallel with said capacitor.

7. The apparatus of claim 6 wherein said capacitor is a DC-blocking capacitor connected to said simulator.

8. The apparatus of claim 6 wherein said capacitor is from 0.01 to 1 microfarad.

9. The apparatus of claim 2 wherein said test load includes a resistive load connected to be in parallel with said portion of the patient'"'"'s body and said signal generator when said means for transmitting said pulse pair is connected to said patient'"'"'s body.

10. The apparatus of claim 1 wherein said test load continuously receives said first and second pulses.

11. The apparatus of claim 1 wherein said test load periodically receives said first and second pulses.

12. The apparatus of claim 11 including means for disconnecting said signal generator from said means for electrically transmitting said pulse pair when said monitor is comparing said first and second pulses.

13. An impedance measuring apparatus for use in controlling a cardiac stimulator apparatus, said measuring apparatus comprising:

a circuit for generating biphasic current pulse pairs;

means for applying said pulse pairs to a portion of said patient'"'"'s body;

means for determining impedance of said portion of said patient'"'"'s body from said applied pulse pairs; and

monitor means connected to said circuit for determining whether each of said current pulse pairs is substantially electrically balanced.

14. The apparatus of claim 13 wherein said means for applying comprises a lead for connection to the heart.

15. The apparatus of claim 14 wherein said monitor means comprises means for continuously monitoring whether said current pulses are substantially balanced.

16. The apparatus of claim 14 including a switching system connected between said monitor means and said circuit means, said system conducting selected current pulse pairs to said monitor means.

17. The apparatus of claim 16 wherein said switching system disconnects said means for applying said pulse pairs to said portion of a patient'"'"'s body when said selected pulse pairs are conducted to said monitor means.

18. A method for cardiac stimulation comprising the steps of:

stimulating the patient'"'"'s heart;

measuring impedance within the patient'"'"'s body, said measuring step including the steps of

producing a biphasic current pulse pair, said pulse pair having a first pulse having current flowing in a first direction and a second pulse having current flowing in a second direction and

transmitting said pulse pairs through a connection to at least a portion of the patient'"'"'s body;

controlling the stimulating of the patient'"'"'s heart as a function of said measure impedance;

monitoring at least some of said first and second pulses to determine whether said pulse pairs are not substantially electrically balanced; and

adjusting said current pulse pairs in response to said determination.

19. The method of claim 18 wherein the step of monitoring said pulse pairs comprises monitoring substantially all said pulse pairs.

20. The method of claim 18 including the step of disconnecting the connection to the portion of the patient'"'"'s body when monitoring said pulse pairs.

21. The method of claim 18 including the steps of detecting intrinsic signals in the body of the patient and blanking the monitoring of said pulse pairs in response to the detection of said signals.

22. The method of claim 21 wherein the step of detecting intrinsic signals includes detecting intracardiac signals.

23. The method of claim 18 wherein the step of monitoring includes the steps of producing signals proportional to the amplitude and duration of each pulse and comparing said signals.

24. The method of claim 23 wherein the step of comparing said signals includes the step of combining signals corresponding to said first pulses with signals corresponding to said second pulses.

25. The method of claim 24 wherein the step of combining said signals includes adding said signals.

26. The method of claim 18 including the step of terminating the impedance measuring when said monitoring determines that a pulse pair is not substantially balanced.