Delivery system comprising means for governing fluid ingress into the system
First Claim
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1. A delivery system for delivering a beneficial agent to a fluid biological environment of use, wherein the delivery system comprises:
- (1) a housing member comprising;
(2) a lead end and a rear end;
(3) an exit in the lead end;
(4) a wall closed and continuous the length of the housing member;
the wall comprising;
(5) a first section impermeable to the passage for fluid and joined in a fluid tight arrangement with;
(6) a second section permeable to the passage for fluid;
(7) in the first section;
(a) a beneficial agent that is sensitive to fluid; and
(b) a carrier for the beneficial agent, wherein said first section protects the beneficial agent from fluid in the environment of use;
(8) an osmopolymer as push means in the second section for delivering the beneficial agent through the exit from the delivery system; and
(9) a layer interposed between the first and second sections, said layer being sufficiently impermeable to restrict passage for fluid from the second section into the first, beneficial agent, section, said layer acting to slide into the first section, aiding in the delivery of beneficial agent, when the push means expands.
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Abstract
A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
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Citations
11 Claims
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1. A delivery system for delivering a beneficial agent to a fluid biological environment of use, wherein the delivery system comprises:
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(1) a housing member comprising; (2) a lead end and a rear end; (3) an exit in the lead end; (4) a wall closed and continuous the length of the housing member;
the wall comprising;(5) a first section impermeable to the passage for fluid and joined in a fluid tight arrangement with; (6) a second section permeable to the passage for fluid; (7) in the first section;
(a) a beneficial agent that is sensitive to fluid; and
(b) a carrier for the beneficial agent, wherein said first section protects the beneficial agent from fluid in the environment of use;(8) an osmopolymer as push means in the second section for delivering the beneficial agent through the exit from the delivery system; and (9) a layer interposed between the first and second sections, said layer being sufficiently impermeable to restrict passage for fluid from the second section into the first, beneficial agent, section, said layer acting to slide into the first section, aiding in the delivery of beneficial agent, when the push means expands. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification