Method of treating movement disorders by brain stimulation
First Claim
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1. A method of therapeutically treating a movement disorder resulting in abnormal motor behavior by means of a signal generator and an implantable electrode having a proximal end and a stimulation portion comprising the steps of:
- surgically implanting said electrode in a brain of a patient so that the stimulation portion lies in communication with a predetermined treatment site in the brain, said predetermined treatment site being selected from the group consisting of the pallido-thalamic axons (AL), the lenticulo-thalamic fiber pathway (LT), substantia nigra pars reticulata (SNr), external segment of globus pallidus (GPe), subthalamic to pallidal fiber tracts, putamen, and putamen to GPe fibers;
coupling said proximal end of said electrode to said signal generator; and
operating said signal generator to stimulate said predetermined treatment site in the brain,whereby the symptoms of said movement disorder are reduced.
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Abstract
Techniques for stimulating the brain to treat movement disorders resulting in abnormal motor behavior by means of an implantable signal generator and electrode. A sensor is used to detect the symptoms resulting from the motion disorder. A microprocessor algorithm analyzes the output from the sensor in order to regulate the stimulation delivered to the brain.
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Citations
18 Claims
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1. A method of therapeutically treating a movement disorder resulting in abnormal motor behavior by means of a signal generator and an implantable electrode having a proximal end and a stimulation portion comprising the steps of:
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surgically implanting said electrode in a brain of a patient so that the stimulation portion lies in communication with a predetermined treatment site in the brain, said predetermined treatment site being selected from the group consisting of the pallido-thalamic axons (AL), the lenticulo-thalamic fiber pathway (LT), substantia nigra pars reticulata (SNr), external segment of globus pallidus (GPe), subthalamic to pallidal fiber tracts, putamen, and putamen to GPe fibers; coupling said proximal end of said electrode to said signal generator; and operating said signal generator to stimulate said predetermined treatment site in the brain, whereby the symptoms of said movement disorder are reduced. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of treating a movement disorder resulting in abnormal motor behavior comprising in combination:
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implanting a signal generator in a body; implanting at least one electrode in at least one predetermined site in a brain of said body; coupling said at least one electrode to said signal generator; generating a signal related to the extent of said abnormal motor behavior; generating stimulation pulses with said signal generator; and regulating said stimulation pulses in response to said signal, whereby the stimulation is increased in response to an increase in said abnormal motor behavior and is decreased in response to a decrease in said abnormal motor behavior. - View Dependent Claims (14, 15, 16, 17, 18)
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Specification