Method and apparatus for inspecting a rotating medicine vial with cameras

• US 5,719,679 A
• Filed: 08/25/1995
• Issued: 02/17/1998
• Est. Priority Date: 09/01/1994
• Status: Expired due to Term

• Current Assignee: Eisai Machinery Co. Ltd. (Syntegon Technology GmbH)
• Original Assignee: Eisai Company Limited (Eisai Medical Research Incorporated)
• Inventors: Shimizu, Koji, Maruoka, Kazumi
• Primary Examiner(s): Font, Frank G.
• Assistant Examiner(s): VIERRA EISENBERG, JASON D
• Application Number:
  US08/519,185
• Time in Patent Office: 907 Days
• Field of Search: 356/427-428, 356/239-240, 250/223 B, 250/224
• US Class Current: 356/428
• CPC Class Codes: G01N 21/9009 Non-optical constructional details affecting optical inspection, e.g. cleaning mechanisms for optical parts, vibration reduction
• CPC Class Codes: G01N 21/9027 in containers after filling
• CPC Class Codes: G01N 21/9036 using arrays of emitters or receivers

Abstract

A method is for inspecting a vial in the course of conveying the vial by a rotary table, comprising the steps of inspecting the vial'"'"'s lower half at a station of the vial'"'"'s lower portion while the vial is rotated from above with its head being chucked, inspecting the vial'"'"'s upper half at a station of the vial'"'"'s upper portion while the vial is supported and rotated from below by a rotary belt adapted to be brought into contact with the vial, and combining these inspections of lower and upper halves to inspect the whole vial from its head to its bottom.

Claims

1. A method for inspecting a vial comprising a body and a head and having a content therein, and wherein the inspection is completed and continuously achieved without being obstructed by a vial supporting mechanism, and wherein the inspection includes inspection of a lower portion of the vial and inspection of an upper portion of the vial, comprising:

1) applying a chuck to the head of the vial so as to grasp the head and suspend the vial;

2) rotating the chuck so as to rotate the suspended vial;

3) illuminating the vial with at least one light while the vial is rotated by the chuck;

4) imaging the illuminated vial with at least one camera and displaying the image;

5) inspecting the lower portion of the vial from the displayed image for abnormal contents, foreign substances on faces on the content and defects in the vial body;

6) releasing the chuck and placing the vial on a support which contacts the bottom of the vial;

7) rotating the vial while on the support;

8) illuminating the vial with at least one light while the vial is rotated on the support;

9) imaging the illuminated vial with at least one camera and displaying the image; and

10) inspecting the upper portion of the vial from the displayed image for defects in the vial head.

2. The method of claim 1, wherein the illumination of step 3 is at least from obliquely below the vial and the camera is located obliquely below the vial such that defects in the vial body are detectable.

3. The method of claim 1, wherein the content is a freeze-dried medicine.

4. The method of claim 3, wherein the illumination of step 3 is at least from below a bottom of the vial and the camera is located obliquely above the vial such that at least foreign substances at a top face of the content are detectable.

5. The method of claim 3, wherein the illumination of step 3 is at least from obliquely above the vial and the camera is located below the vial such that at least foreign substances at a bottom face of the content are detectable.

6. The method of claim 3, wherein the illumination of step 3 is at least from obliquely above the vial and the camera is located laterally of the vial such that at least foreign substances at side faces of the content are detectable.

7. The method of claim 3, wherein the illumination of step 3 is at least from obliquely below the vial and the camera is located obliquely below the vial such that at least abnormal contents are detectable.

8. The method of claim 3, wherein the illumination of step 8 is at least below the vial bottom such that light can propagate along vial walls and the camera is located obliquely upwardly toward the vial head such that at least defects in a mouth of the vial are detectable.

9. The method of claim 1, wherein the illumination of step 8 is at least laterally of the vial such that light is reflected from the vial head and the camera is located laterally of the vial such that at least defects in the vial head are detectable.

10. The method of claim 1, wherein the imaging is performed at separate inspection stations, with each inspection station having different spacial arrangements of the illumination and camera.

11. The method of claim 10, wherein the inspection stations are spaced about a rotatable wheel which conveys the vial from station to station.

12. The method of claim 1, wherein there are a plurality of CCD cameras and lights.

13. An apparatus for inspecting a vial comprising a body and a head and having a content therein, and wherein the inspection is completely and continuously achieved without being obstructed by a vial supporting mechanism, and wherein the inspection includes inspection of a lower portion of the vial and inspection of an upper portion of the vial, comprising:

1) a chuck configured to releasably grasp the head of the vial and suspend the vial;

2) chuck rotation means for rotating the chuck so as to rotate the vial while being suspended;

3) at least one first light for illuminating the vial while the vial is being rotated by the chuck;

4) at least one first camera for imaging the illuminated vial and display means for displaying the image such that the display will show in the lower portion of the vial any abnormal contents, foreign substances on the face of the content, and defects in the vial body;

5) releasing means for releasing the chuck and releasing the vial;

6) a support for supporting the bottom of the released vial;

7) vial rotation means for rotating the vial while supported by the support;

8) at least one second light for illuminating the vial while the vial is being rotated;

9) at least one second camera for imaging the illuminated vial and display means for displaying the image such that the display will show in the upper portion of the vial defects in the vial head; and

10) a rotatable table for moving the vial to and from successive inspection stations.

14. The apparatus of claim 13, wherein the first light is positioned at least obliquely below the vial and the first camera is located obliquely below the vial such that defects in the vial body are detectable.

15. The apparatus of claim 13, wherein the content is a freeze-dried medicine.

16. The apparatus of claim 15, wherein the first light is at least disposed below a bottom of the vial and the camera is located obliquely above the vial such that at least foreign substances at a top face of the content are detectable.

17. The apparatus of claim 15, wherein the first light is at least disposed obliquely above the vial and the camera is located below the vial such that at least foreign substances at a bottom face of the content are detectable.

18. The apparatus of claim 15, wherein the first light is at least disposed obliquely above the vial and the camera is located laterally of the vial such that at least foreign substances on side faces of the content are detectable.

19. The apparatus of claim 15, wherein the first light is at least disposed obliquely below the vial and the camera is located obliquely below the vial such that at least abnormal contents are detectable.

20. The apparatus of claim 15, wherein the second light is at least disposed below a vial bottom such that light can propagate along vial walls and the camera is located obliquely upwardly toward the vial head such that at least defects in a mouth of the vial are detectable.

21. The apparatus of claim 13, wherein the second light is at least disposed laterally of the vial such that light is reflected from the vial head and the camera is located laterally of the vial such that at least defects in the vial head are detectable.

22. The apparatus of claim 13, wherein the cameras are disposed at separate inspection stations, with each inspection station having a different spacial arrangement of the light and camera.

23. The apparatus of claim 22, wherein the inspection stations are spaced about a rotatable table.

24. The apparatus of claim 13, wherein there are a plurality of CCD cameras and lights.

25. Apparatus of claim 13, wherein the chuck includes a lower holder provided with anchor-shaped links adapted to be swung by a pusher and thereby to open and close chuck fingers, an outer shaft, and an inner shaft connected to said pusher and adapted to be vertically moved together with the outer shaft for a predetermined distance, and the inner shaft is thereafter slidably movable independently of said outer shaft.

26. Apparatus of claim 25, further comprising a mechanism for rotationally driving the outer shaft and a mechanism for vertically moving and closing the chuck.

27. Apparatus of claim 26, wherein the mechanism for vertically moving and closing the chuck comprises a combination of a mechanical valve and an air cylinder.

28. Apparatus of claim 13, wherein the apparatus includes an image processor adapted for processing in parallel images picked up by one or more CCD cameras and pixel counts.