Therapy and imaging probe and therapeutic treatment apparatus utilizing it

• US 5,720,287 A
• Filed: 06/06/1996
• Issued: 02/24/1998
• Est. Priority Date: 07/26/1993
• Status: Expired due to Fees

• Current Assignee: Technomed Medical Systems
• Original Assignee: Technomed Medical Systems
• Inventors: Lacoste, Francois, Blanc, Emmanuel, Chapelon, Jean-Yves
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SHAW, SHAWNA JEANNINE
• Application Number:
  US08/659,581
• Time in Patent Office: 628 Days
• Field of Search: 128/660.01, 128/660.03, 128/662.03, 128/662.06, 601/2, 601/3, 600/102, 600/160, 607/97, 310/369
• US Class Current: 600/439
• CPC Class Codes: A61B 18/00 Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body eye surgery A61F9/007; ear surgery A61F11/00
• CPC Class Codes: A61B 2017/00106 ultrasonic
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4209 by using holders, e.g. positioning frames
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/4461 Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
• CPC Class Codes: A61N 7/022 intracavitary
• CPC Class Codes: G10K 11/35 using mechanical steering of transducers or their beams
• CPC Class Codes: G10K 11/355 Arcuate movement

Abstract

The therapy and imaging probe of the invention comprises a probe body (20'"'"') of an elongate shape defining a general axis (X--X), one imaging transducer (40'"'"') for transmitting imaging waves, and one therapy transducer (30'"'"') for transmitting therapy waves. The imaging transducer is mounted on first support means providing translational movement of the imaging transducer within the probe, parallel to the general axis (X--X) of the probe, between a withdrawn position and an extended position. The therapy transducer is mounted on second support means providing rotation of the therapy transducer within the probe, about an axis of rotation (X1--X1) parallel to the general axis (X--X) of the probe but offset with respect to the imaging transducer, to allow rotation of the therapy transducer between a withdrawn position and a treatment position. In the withdrawn or non-active position of the therapy transducer, the imaging transducer may be brought by translational movement to its extended position to occupy the place occupied by the therapy transducer in its treatment position. Thus, the imaging transducer may form an image of a region for treatment by the therapy transducer. In the treatment position of the therapy transducer, the imaging transducer is at its withdrawn position. The therapy transducer, during the transmission of therapy waves, directly transmits the therapy waves in a direction substantially identical to the direction in which the imaging transducer transmits the imaging waves when imaging waves are being transmitted.

Claims

1. A therapy and imaging probe comprising:

a probe body of an elongate shape defining a general axis;

at least one imaging transducer for transmitting imaging waves, said imaging transducer being mounted on first support means providing translational movement of said imaging transducer within said probe body, substantially parallel to said general axis of said probe body, between a withdrawn position and an extended position;

at least one therapy transducer for transmitting therapy waves, said therapy transducer being mounted on second support means providing rotation of said therapy transducer within and relative to said probe body, about an axis of rotation substantially parallel to said general axis of said probe but offset with respect to said imaging transducer;

said second support means providing rotation of said therapy transducer between a treatment position for which said imaging transducer is at a withdrawn position, and a withdrawn position for which said imaging transducer may be brought by translational movement to its extended position to occupy the place occupied by said therapy transducer in its treatment position; and

a direction of transmission of therapy waves by said therapy transducer in its treatment position being substantially identical to a direction of transmission of imaging waves by said imaging transducer in its extended position.

2. A therapy and imaging probe according to claim 1, wherein said axis of rotation of said therapy transducer is outside a largest dimension of said imaging transducer.

3. A therapy and imaging probe according to claim 1, wherein said therapy transducer and said imaging transducer are arranged inside a flexible membrane filled with an acoustic-coupling liquid such as water or an oil.

4. A therapy and imaging probe according to claim 1, wherein said therapy transducer is mounted in a support member integral with said second support means and having a cross-section in a plane perpendicular to said general axis of said probe defining a perimeter which is close to a perimeter of a cross-section taken in said plane of said therapy transducer.

5. A therapy and imaging probe according to claim 4, wherein an external shape of said therapy transducer is that of a disc, a profile of which is for a major part substantially circular, but having a reduced diameter in a direction perpendicular to said general axis of said probe.

6. A therapy and imaging probe according to claim 1, wherein said imaging transducer is arranged to provide images in several planes.

7. A therapy and imaging probe according to claim 6, wherein said imaging transducer is arranged to provide images in two perpendicular planes, comprising a radial plane, perpendicular to said general axis of said probe, and a sagittal plane, containing said general axis thereby making it possible to also provide imaging when said imaging transducer is in said withdrawn position and said therapy transducer is in said treatment position.

8. A therapy and imaging probe according to claim 1, wherein said therapy transducer provides focusing in a direction substantially perpendicular to said general axis.

9. A therapy and imaging probe according to claim 4, wherein said support member for said therapy transducer has a substantially circular outside shape, close to an outer shape of a substantially circular-shaped therapy transducer, said support member being integral with said second support means close to an edge of said support member, thereby facilitating movement of said therapy transducer between said withdrawn position and said treatment position.

10. A therapy and imaging probe according to claim 9, wherein in said treatment position, the outer shape of said therapy transducer defines a plane that contains said general axis.

11. A therapy and imaging probe according to claim 4, wherein said support member for said therapy transducer has a substantially polygonal outside shape, close to an outer shape of a substantially polygonal-shaped therapy transducer, said support member being integral with said second support means close to an edge of said support member, thereby facilitating movement of said therapy transducer between said withdrawn position and said treatment position.

12. A therapy and imaging probe according to claim 11, wherein in said treatment position, the outer shape of said therapy transducer defines a plane that contains said general axis.

13. A therapy and imaging probe according to claim 1, comprising means for providing manual rotation of said therapy transducer, and means for providing manual translational movement of said imaging transducer.

14. A therapy and imaging probe according to claim 1, comprising means for providing motor-driven rotation of said therapy transducer, and means for providing motor-driven translational movement of said imaging transducer.

15. A therapy and imaging probe according to claim 1, wherein said therapy transducer has a ratio between diameter and focal length comprised between 0.8 and 1.5.

16. A therapy and imaging probe according to claim 15, wherein said therapy transducer has a ratio between diameter and focal length of substantially.

17. A therapy and imaging probe according to claim 1, comprising means for making said therapy transducer deliver ultrasound waves pulsed at a frequency comprised between 1 and 4 MHz and with a short pulse duration comprised between 50 ms and 5 s, with an intensity at a focal point F comprised between 1,000 and 10,000 W/cm2.

18. A therapy and imaging probe according to claim 17, wherein said short pulse duration is comprised between 1 and 4 s.

19. A therapy and imaging probe according to claim 1, wherein said therapy transducer comprises a mechanically-deformable lens allowing modification of the focal length thereof.

20. A therapy and imaging probe according to claim 1, comprising a rigid wall at least partially surrounding said transducers.

21. A therapy and imaging probe according to claim 20, wherein said rigid wall includes a window.

22. A therapy and imaging probe according to claim 1, comprising a locally-deformable flexible casing.

23. Treatment apparatus, comprising a therapy and imaging probe as defined in claim 1.

24. Treatment apparatus according to claim 23, for treating a target region inside the body of a mammal, comprising means for introducing said probe into a body cavity.

25. Treatment apparatus according to claim 24, wherein said target region is a tissue region of a non-malignant tumor of a body of a human being.

26. Treatment apparatus according to claim 24, wherein said target region is a tissue region of a malignant tumor of a body of a human being.

27. Treatment apparatus according to claim 24, for treating prostate tissue of a body of a human being by urethral or rectal route.

28. A method for treating a target region inside the body of a mammal, comprising:

providing a probe including;

(i) a probe body of an elongate shape defining a general axis;

(ii) an imaging transducer for transmitting imaging waves, said imaging transducer being mounted on first support means providing translational movement of said imaging transducer within said probe body, substantially parallel to said general axis of said probe body, between a withdrawal position and an extended position; and

(iii) a therapy transducer for transmitting therapy waves, said therapy transducer being mounted on second support means providing rotation of said therapy transducer within and relative to said probe body, about an axis of rotation substantially parallel to said general axis of said probe body but offset with respect to said imaging transducer, said second support means providing rotation of said therapy transducer between a treatment position for which said imaging transducer is at a withdrawn position, and a withdrawn position for which said imaging transducer may be brought by translational movement to its extended position to occupy the place occupied by said therapy transducer in its treatment position;

introducing said probe into a body cavity until said therapy transducer in its treatment position is substantially facing said target region;

rotating said therapy transducer relative to said probe body in order to position it in said withdrawn position;

moving said imaging transducer with a translational movement into said extended position to occupy the place occupied by said therapy transducer in its treatment position;

forming an image with said imaging transducer of said target region to be treated by said therapy transducer allowing said target region to be viewed;

withdrawing said imaging transducer into said withdrawn position;

rotating said therapy transducer relative to said probe body to bring it to said treatment position; and

delivering ultrasonic treatment waves during a predetermined interval necessary for performing said treatment.

29. A method according to claim 28, wherein said mammal is a human being, said a target region comprises prostate tissue, and said body cavity is a urethra of said human being.

30. A method according to claim 28, wherein said mammal is a human being, said a target region comprises prostate tissue, and said body cavity is a rectum of said human being.