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Antibodies and fragments thereof which bind the carboxyl-terminus of an amino-terminal fragment of .beta.APP

  • US 5,721,130 A
  • Filed: 05/12/1995
  • Issued: 02/24/1998
  • Est. Priority Date: 04/15/1992
  • Status: Expired due to Term
First Claim
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1. An antibody composition comprising antibody molecules that specifically recognize an amino-terminal fragment of β

  • APP which is cleaved at the amino-terminus of β

    -amyloid peptide, but which antibody molecules do not specifically recognize a secreted fragment of β

    APP whose sequence extends into the sequence of β

    -amyloid peptide.

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