Rate responsive cardiac pacemaker and method for discriminating stair climbing from other activities

• US 5,725,562 A
• Filed: 06/28/1996
• Issued: 03/10/1998
• Est. Priority Date: 03/30/1995
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sheldon, Todd J.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/668,524
• Time in Patent Office: 620 Days
• Field of Search: 607/17, 607/19, 607/62
• US Class Current: 607/19
• CPC Class Codes: A61N 1/36535 controlled by body position or posture
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

A method of and apparatus for pacing a patient'"'"'s heart at a pacing rate dependent on patient activity and posture particularly during stair climbing. A dual chamber, rate responsive pacemaker for pacing a patient'"'"'s heart includes at least one DC accelerometer mounted in the pacemaker pulse generator for implantation such that the sensitive axis of the DC accelerometer is sensitive to the effects of gravity during forward lean of the patient characteristic of stair climbing posture. The DC and AC signal outputs of the accelerometer are processed to develop a tilt signal and an activity signal. A target rate control signal is derived from the activity signal dependent on the level of activity. A stair climbing rate is selected for controlling the physiologic pacing rate between a lower and an upper pacing rate in the presence of an activity signal indicative of a patient walking rate and a tilt signal value falling within a tilt window. The target rate control signal is used to control the pacing rate if the activity signal is indicative of faster patient movement, e.g. running, or if the tilt signal is outside the tilt window indicating that the patient is either upright or prone.

Claims

1. A method of pacing a patient'"'"'s heart at a pacing rate dependent on patient activity and posture particularly during stair climbing comprising the steps of:

deriving a body posture tilt signal having a characteristic varying with the degree to which the patient posture is in an upright stance or leaning forward;

detecting patient footsteps;

deriving a patient activity signal having a signal level dependent on the frequency of patient footsteps recurring over a time unit;

deriving a rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart;

defining physiologic escape intervals as a function of the rate control signal to establish a physiologic pacing rate;

generating pacing pulses at the physiologic pacing rate; and

applying the pacing pulses to the patient'"'"'s heart.

2. The method of claim 1 wherein the step of deriving a body posture tilt signal further comprises measuring the forces of acceleration in the anterior-posterior axis of the patient'"'"'s body recurring in a first predetermined low frequency range and deriving a measured tilt signal therefrom.

3. The method of claim 2 wherein the step of detecting patient footsteps further comprises measuring the forces of acceleration in the anterior-posterior axis of the patient'"'"'s body recurring in a second predetermined frequency. range higher in frequency than said first predetermined low frequency range and deriving the patient activity signal therefrom.

4. The method of claim 3 wherein the steps of deriving a body posture tilt signal and detecting patient footsteps further comprise the steps of:

mounting a solid state DC accelerometer having a sensitive axis of deflection and providing an output signal varying in magnitude in response to the DC force of gravity and AC forces of acceleration applied along the sensitive axis in a pacemaker pulse generator;

implanting the pulse generator in the patient with the second sensitive axis generally aligned with the patient'"'"'s anterior-posterior body direction while the patient is in the upright stance;

deriving a forward tilt signal from the output signal of a polarity and magnitude varying in response to the DC force of gravity and representative of the degree to which the patient is leaning forward from an upright stance; and

detecting the patient footsteps from the output signal varying in magnitude in response to the AC forces of acceleration applied along the sensitive axis.

5. The method of claim 4 wherein the step of deriving a pacing rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart further comprises:

providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

providing a stair climbing rate control signal;

comparing the body posture tilt signal to a tilt window;

when the body posture tilt signal is within the tilt window, employing the stair climbing rate control signal as the pacing rate control signal; and

when the body posture tilt signal is outside the tilt window, employing the target rate control signal as the pacing rate control signal.

6. The method of claim 5 further comprising the step of comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal.

7. The method of claim 1 wherein the step of deriving a pacing rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart further comprises:

providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

providing a stair climbing rate control signal;

comparing the body posture tilt signal to a tilt window;

when the body posture tilt signal is within the tilt window, employing the stair climbing rate control signal as the pacing rate control signal; and

when the body posture tilt signal is outside the tilt window, employing the target rate control signal as the pacing rate control signal.

8. The method of claim 7 further comprising the step of comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal.

9. The method of claim 1 wherein the step of deriving a pacing rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart further comprises:

providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

providing a stair climbing rate control signal;

comparing the body posture tilt signal to an inner and an outer tilt window;

when the body posture tilt signal is within the inner and the outer tilt windows, employing the stair climbing rate control signal as the pacing rate control signal;

when the body posture tilt signal is outside the outer tilt window, employing the target rate control signal as the pacing rate control signal; and

when the body posture tilt signal is within the outer tilt window and outside the inner tilt window, deriving an intermediate rate control signal and employing the intermediate rate control signal as the pacing rate control signal.

10. The method of claim 9 further comprising the step of comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal whether or not the body posture tilt signal is within the inner or outer tilt windows.

11. The method of claim 1 wherein the steps of deriving a body posture tilt signal and detecting patient footsteps further comprise the steps of:

mounting a solid state DC accelerometer having a sensitive axis of deflection and providing an output signal varying in magnitude in response to the DC force of gravity and AC forces of acceleration applied along the sensitive axis in a pacemaker pulse generator;

implanting the pulse generator in the patient with the second sensitive axis generally aligned with the patient'"'"'s anterior-posterior body direction while the patient is in the upright stance;

deriving a forward tilt signal from the output signal of a polarity and magnitude varying in response to the DC force of gravity and representative of the degree to which the patient is leaning forward from an upright stance; and

detecting the patient footsteps from the output signal varying in magnitude in response to the AC forces of acceleration applied along the sensitive axis.

12. The apparatus of claim 1 wherein the means for deriving a body posture tilt signal further comprises means for measuring the forces of acceleration in the anterior-posterior axis of the patient'"'"'s body recurring in a first predetermined low frequency range and deriving a measured tilt signal therefrom.

13. The apparatus of claim 12 wherein the means for detecting patient activity further comprises means for measuring the forces of acceleration in the anterior-posterior axis of the patient'"'"'s body recurring in a second predetermined frequency range higher in frequency than said first predetermined low frequency range and deriving the patient activity signal therefrom.

14. The apparatus of claim 13 wherein the means for deriving a body posture tilt signal and the means for detecting patient activity further comprise:

means for responding to the force of gravity on the patient'"'"'s body along a generally anterior-posterior axis of the patient'"'"'s body and deriving a forward tilt signal therefrom of a polarity and magnitude representative of the degree to which the patient is leaning forward from an upright stance; and

means for measuring forces of acceleration in the patient'"'"'s body due to patient footsteps and deriving a patient activity signal therefrom representative of patient footsteps.

15. The apparatus of claim 14 wherein the means for deriving a pacing rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart further comprises:

means for providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

means for providing a stair climbing rate control signal;

means for comparing the body posture tilt signal to a tilt window;

means for employing the stair climbing rate control signal as the pacing rate control signal when the body posture tilt signal is within the tilt window; and

means for employing the target rate control signal as the pacing rate control signal when the body posture tilt signal is outside the tilt window.

16. The apparatus of claim 15 further comprising means for comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal.

22. The apparatus of claim 12 wherein the means for deriving a body posture tilt signal and the means for detecting patient activity further comprise:

means for responding to the force of gravity on the patient'"'"'s body along a generally anterior-posterior axis of the patient'"'"'s body and deriving a forward tilt signal therefrom of a polarity and magnitude representative of the degree to which the patient is leaning forward from an upright stance; and

means for measuring forces of acceleration in the patient'"'"'s body due to patient footsteps and deriving a patient activity signal therefrom representative of patient footsteps.

17. Apparatus for pacing a patient'"'"'s heart at a pacing rate dependent on patient activity and posture particularly during stair climbing comprising:

means for deriving a body posture tilt signal having a characteristic varying with the degree to which the patient posture is in an upright stance or leaning forward;

means for detecting patient activity and for deriving a patient activity signal having a signal level dependent on the frequency and magnitude of patient activity;

means for deriving a rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart;

means for defining physiologic escape intervals as a function of the rate control signal to establish a physiologic pacing rate;

means for generating pacing pulses at the physiologic pacing rate; and

means for applying the pacing pulses to the patient'"'"'s heart.

18. The apparatus of claim 17 wherein the means for deriving a pacing rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart further comprises:

means for providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

means for providing a stair climbing rate control signal;

means for comparing the body posture tilt signal to a tilt window;

means for employing the stair climbing rate control signal as the pacing rate control signal when the body posture tilt signal is within the tilt window; and

means for employing the target rate control signal as the pacing rate control signal when the body posture tilt signal is outside the tilt window.

19. The apparatus of claim 18 further comprising the means for comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal.

20. The apparatus of claim 17 wherein the means for deriving a pacing rate control signal from the body posture tilt signal and the patient activity signal correlated to the physiologic demand on the patient'"'"'s heart further comprises:

means for providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

means for providing a stair climbing rate control signal;

means for comparing the body posture tilt signal to a tilt window;

means for employing the stair climbing rate control signal as the pacing rate control signal when the body posture tilt signal is within the tilt window;

means for employing the target rate control signal as the pacing rate control signal when the body posture tilt signal is outside the tilt window; and

means for deriving an intermediate rate control signal and employing the intermediate rate control signal as the pacing rate control signal when the body posture tilt signal is within the outer tilt window and outside the inner tilt window.

21. The apparatus of claim 20 further comprising means for comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal whether or not the body posture tilt signal is within the inner or outer tilt windows.

23. In a pacemaker pulse generator adapted to be implanted in a patient'"'"'s body, apparatus for pacing a patient'"'"'s heart at a pacing rate dependent on patient activity and body posture particularly to provide adequate cardiac output during stair climbing comprising:

means for responding to the force of gravity on the patient'"'"'s body and deriving a tilt signal therefrom of a polarity and magnitude representative of the degree to which the patient is leaning forward from an upright stance;

means for measuring forces of acceleration in the patient'"'"'s body due to patient footsteps and deriving a patient activity signal therefrom representative of patient footsteps;

means operable in the presence of the tilt signal and the activity signal for providing a stair climbing rate control signal correlated to the physiologic demand on the patient'"'"'s heart appropriate for patient stair ascending;

means for defining physiologic escape intervals as a function of the stair climbing rate control signals to establish a physiologic pacing rate;

means for generating pacing pulses at the physiologic pacing rate; and

means for applying the pacing pulses to a chamber of a patient'"'"'s heart.

24. The pulse generator of claim 23 wherein said measuring means further comprises:

a DC accelerometer mounted in said pulse generator and having an anterior-posterior sensitive axis of deflection, whereby said pulse generator may be implanted with the anterior-posterior sensitive axis generally aligned to a patient'"'"'s anterior-posterior body direction while in a standing upright posture, said DC accelerometer providing the tilt signal varying in magnitude in response to the DC force of gravity and polarity in response to the tilt of the sensitive axis with respect to the direction of the force of gravity.

25. The pulse generator of claim 24 wherein said rate control signal providing means further comprises:

means for defining a tilt window of a range of tilt signal values; and

means operable in the presence of an activity signal for comparing the magnitude of the tilt signal to said tilt signal window and for determining that the patient is climbing stairs when the tilt signal value falls within the tilt window range.

26. The pulse generator of claim 25 wherein the means for providing a stair climbing rate control signal further comprises:

means for providing a target rate control signal for pacing the patient'"'"'s heart as a function of the patient activity signal;

means for providing a stair climbing rate control signal;

means for comparing the tilt signal to a tilt window;

means for employing the stair climbing rate control signal as the pacing rate control signal when the tilt signal is within the tilt window; and

means for employing the target rate control signal as the pacing rate control signal when the tilt signal is outside the tilt window.

27. The apparatus of claim 26 further comprising the means for comparing the target rate control signal with the stair climbing rate control signal and employing the greater as the pacing rate control signal.